Cytokeratin, pan MBS438464 from MyBioSource.com

Product Specs
ItemCytokeratin, pan
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438464
ReactivityHu, Ms, Rb, Rt, Bv, Ck, Dg, Mk
ClonalityMonoclonal
NCBI Gene AliasesKRT1A, EPPK, EHK1, K1, CK1, NEPPK, EHK
NCBI Full Gene Namekeratin 1, type II
ApplicationsWB, FCM, IF, IHC
ImmunogenTwenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas
HostMouse
CloneSPM115 + ; SPM116
Molecular Weight40-60kDa
IsotypeIgG1
TargetCytokeratin
Conjugate/TagUnconjugated
Quantity0.1 mg