The MTCH2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MTCH2. This antibody recognizes Human, and Mouse antigen. The MTCH2 Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway