MyBioSource.com's MOUSE ANTI PIG CD4a Antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunohistochemistry.
Description
Mouse anti Porcine CD4a, clone MIL17 recognizes a 55kDa porcine homologue to the human CD4 antigen found on the surface of helper-T cells. MIL-17 was confirmed as a member of the CD4a cluster at the ˜Third International Workshop on Swine Leukocyte Differentiation Antigens' (Haverson et al. 2001). Porcine CD4 is a type 1 trans-membrane member of the immunoglobulin superfamily. Pigs appear unusual amongst mammalian species as they appear to have four populations of resting T lymphocytes. In addition to the two populations of mutually exclusive CD4+/CD8- and CD4-/CD8+ lymphocytes, they also appear to have significant populations of CD4-/CD8- and CD4+/CD8+ cells. Lymphoblasts with a double positive phenotype have been described in other species but this is not the case for mature T lymphocytic calls (Saalmuller et al. 1987) Mouse anti Pig CD4a, clone MIL17 stains a population of cells with characteristic lymphocyte morphology in immunohistochemistry (Inman et al. 2010)