The SUMO2/SUMO3/SUMO4 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SENTRIN-2, and SUMO2. This antibody recognizes Human, Mouse, and Rat antigen. The SUMO2/SUMO3/SUMO4 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized