The PDE5A Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PDE5, PDE5A, and phosphodiesterase 5A. This antibody recognizes Human, Mouse, and Rat antigen. The PDE5A Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms