The SIPA1L2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SIPA1L2. This antibody recognizes Human, Mouse, and Rat antigen. The SIPA1L2 Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis