MyBioSource.com's SFRP1 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The SFRP1 Polyclonal Antibody was generated using SFRP1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. Interacts with WNT1, WNT2 and FRZD6. Interacts with WNT4 and WNT8