MyBioSource.com's ASB2 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The ASB2 Antibody (N-term) was generated using ASB2 as the antigen and it reacts with Human.
Description
The protein encoded by this gene is a member of the
ankyrin repeat and SOCS box-containing (ASB) family of proteins.
They contain ankyrin repeat sequence and SOCS box domain. The SOCS
box serves to couple suppressor of cytokine signalling (SOCS)
proteins and their binding partners with the elongin B and C
complex, possibly targeting them for degradation. This gene is
induced by all-trans retinoic acid. In myeloid leukemia cells, the
expression of this encoded protein has been shown to induce growth
inhibition and chromatin condensation. Multiple alternatively
spliced transcript variants have been described for this gene but
their full length sequences are not known