Abbexa Ltd's Runt-Related Transcription Factor 2 (RUNX2) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Runt-Related Transcription Factor 2 (RUNX2) Antibody was generated using RUNX family transcription factor 2, and RUNX2 as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
RUNX2 Antibody is a Rabbit Polyclonal antibody against RUNX2. This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing