The TMED10 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Tmed10. This antibody recognizes Human, Mouse, and Rat antigen. The TMED10 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8