The Mouse Anti Human Mevalonate Kinase Antibody from MyBioSource.com is a Mouse Monoclonal antibody to Mevalonate kinase, and MVK. This antibody recognizes Rat antigen. The Mouse Anti Human Mevalonate Kinase Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Introduction: MVK is a member of the GHMP kinase family. Mevalonate is a vital mediator, and MVK an important early enzyme, in isoprenoid and sterol synthesis. MVK deficiency can result in gene mutation associated with Mevalonic aciduria, an illness which causes psychomotor retardation, failure to thrive hepatosplenomegaly, anemia and frequent febrile crises. Mutations in this gene also cause hyperimmunoglobulinaemia D and sporadic fever syndrome, in which the person suffers from recurrent episodes of fever related with lymphadenopathy, skin rash, gastrointestinal dismay and arthralgia