CD4 Antibody

Product Specs
ItemCD4 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberNBP1-19371
ImmunogenA synthetic peptide made to an C-terminal region of the human CD4 Antibody protein (within residues 400-458). [Swiss-Prot P01730]
Concentration1.0 mg/ml
ReactivityCanine,Flow,Human,Mouse,Porcine,Rabbit,Rat
TargetCD4
Conjugate/TagUnconjugated
Quantity0.1 ml (also 0.025 ml)
FormatPBS
ApplicationsIF/IHC,Rabbit,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Dual RNAscope ISH-IHC,Immunocytochemistry/ Immunofluorescence
HostRabbit
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaAdaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Immunology, Innate Immunity, Regulatory Immunology, Signal Transduction, Stem Cell Markers
IsotypeIgG
NCBI Full Gene NameCD4 antigen, CD4 molecule
NCBI Gene AliasesL3T4, CD4mut, T4, OKT4D, IMD79, Leu-3, Ly-4
Antibody TypePrimary Antibodies
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml (also 0.025 ml)

Questions and Answers

Can this CD4 antibody be used to identify T-helper cells in various experimental models?

Yes, the CD4 antibody has been utilized in multiple studies to identify T-helper cells. For instance, it was employed in immunofluorescence staining to analyze the subtypes of infiltrating lymphocytes in a rat model, demonstrating its effectiveness in distinguishing total T-helper lymphocytes (Balzano et al., 2021).

Is this antibody suitable for use in immunohistochemistry for studying immune responses in mouse models?

The CD4 antibody has been shown to work effectively in immunohistochemistry applications. It was used to evaluate cellular infiltration with CD4+ T-cells in heart tissues of mice, indicating its suitability for studying immune responses in various mouse models (Wu et al., 2019).

What species can this antibody react with, and has it been cited in relevant research?

The CD4 antibody is reactive with several species, including human, mouse, rabbit, rat, canine, and porcine. It has been cited in 45 scientific articles, indicating its broad applicability and relevance in various research contexts (Novus Biologicals).

Has this antibody been used in studies related to cancer immunotherapy?

Yes, the CD4 antibody has been utilized in studies investigating immune responses in cancer models. For example, it was part of an analysis assessing T-helper cell-mediated anti-tumor immunity in a study involving pathogen-mimicking nanoparticles, highlighting its role in cancer immunotherapy research (Son et al., 2022).

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Huaier Polysaccharides Sensitize Anti-PD-L1 Therapy via Promoting Antitumor Immune Response in Triple-Negative Breast CancerInt J Biol SciMay 18, 2026Lin-Xi Zhou, Zi-Wei Wu, Yuan Tian, Ke-Fei Luo, Qin-Wen Pan, Yuan-Yin Xi, Peng Tang, Ling-Juan Zeng, Ling Zhong, Jun Jiang, et al.were from Affinity Biosciences (Cincinnati, OH, USA). Anti-PD-L1 (NBP1-43262), LC3 (NB100-2220), CD4 (NBP1-19371), CD8 (NB200-578), FoxP3 (NB100-39002) and Ki67 (NB110-89717) antibodies were from Novus Biologicals

(2) Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical StudiesCurrent Issues in Molecular BiologyDecember 24, 2025Wonwoo Kim, Hyunkyung Kim, Won Il Jang, Mi Sook Kim, Sun Hyun Baeovernight at 4 °C with solutions containing appropriate concentrations of antibodies against CD4 (Cat.NBP1-19371, Novus Biologicals, Centennial, CO, USA), CD8 (Cat.ab4055, Abcam, Waltham, MA, USA), and interferon

(3) MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis ExpressionJ Inflamm ResDecember 6, 2025Yi Li, Xiaocong Li, Tao Gu, Li Wang, Man Song, Liping Yang, Qinghua Huang, Juan Yang(1:100, Proteintech, 19771-1-AP, China), ASC (1:200, Bioss, bs-6741R, China), CD4+ T (1:100, Novus, NBP1-19371, USA), CD68 (1:200, Servicebio, GB113109-100, China) and MBP (1:200, Cell Signaling Technology, 78896S,

(4) MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis ExpressionJ Inflamm ResDecember 6, 2025Yi Li, Xiaocong Li, Tao Gu, Li Wang, Man Song, Liping Yang, Qinghua Huang, Juan Yang(1:100, Proteintech, 19771-1-AP, China), ASC (1:200, Bioss, bs-6741R, China), CD4+ T (1:100, Novus, NBP1-19371, USA), CD68 (1:200, Servicebio, GB113109-100, China) and MBP (1:200, Cell Signaling Technology, 78896S,

(5) Rebamipide Enhances Pathogen Defense and Mitigates Inflammation in a Particulate Matter-Induced Ocular Surface Inflammation Rat ModelInt J Mol SciApril 21, 2025Basanta Bhujel, Se-Heon Oh, Woojune Hur, Seorin Lee, Hun Lee, Ho-Seok Chung, Jae Yong KimDanvers, MA, USA, 1:1000), NF-κB (8242S; Cell Signaling Technology, Danvers, MA, USA, 1:1000), CD-4 (NBP1-19371; Novus Biologicals, Littleton, CO, USA, 1:1000), Bax (sc-20067; Santa Cruz Biotechnology, Dallas, TX,

(6) First-In-DOg HISTotripsy for Intracranial Tumors Trial: The FIDOHIST StudyTechnology in Cancer Research & TreatmentOctober 17, 2024Christina Vezza, Lauren Ruger, Maya Langman, Elliana Vickers, Francesco Prada, Jonathan Sukovich, Timothy Hall, Zhen Xu, Rell L. Parker, Eli Vlaisavljevich, et al.Immunohistochemistry for CD3 (A0452, Dako [Santa Clara, CA, USA], rabbit anti-human polyclonal, 1:150), CD4 (NBP1-19371, Novus Biologicals [Centennial, CO, USA], rabbit anti-human polyclonal, 1:100), CD8 (ab4055, Abcam [Waltham,

(7) H-1 Parvovirus-Induced Oncolysis and Tumor Microenvironment Immune Modulation in a Novel Heterotypic Spheroid Model of Cutaneous T-Cell LymphomaCancers (Basel)July 30, 2024Assia Angelova, Milena Barf, Alexandra Just, Barbara Leuchs, Jean Rommelaere, Guy Ungerechtsfollowing antibodies were used: anti-CD3 (Abcam, ab5690, Cambridge, UK), anti-CD4 (Novus Biologicals, NBP1-19371), anti-vimentin (Abcam, ab8978), anti-pancytokeratin (Abcam, ab86734), and anti-CD31 (Abcam, ab182981),

(8) The Influence of Body Fat Dynamics on Pulmonary Immune Responses in Murine Tuberculosis: Unraveling Sex-Specific InsightsInternational journal of molecular sciencesJune 21, 2024Dhanyalayam D, Thangavel H, Sidrat T, Oswal N, Lizardo K, Mauro M, Zhao X, Xue HH, Desai JV, Nagajyothi JF.Immunohistochemistry (IHC) was performed on the formalin-fixed lung sections using rabbit polyclonal CD4 antibody (#NBP1-19371, Novus Biologicals, Centennial, CO, USA), rabbit polyclonal CD8 antibody (#NBP3-14871, Novus Biologicals,

(9) Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver DamageBiomedicinesAugust 12, 2021Balzano T, Leone P, Ivaylova G, Castro MC, Reyes L, Ramón C, Malaguarnera M, Llansola M, Felipo V.total Th lymphocytes were marked with anti-CD4 (ab846 from Abcam, mouse 1:50 overnight at 4 °C; or NBP1-19371 from Novus (Centennial, CO, USA), rabbit 1:20 overnight at 4 °C). Anti-CX3CR1 (ab8021 from Abcam, rabbit

(10) Noninvasive Radionuclide Molecular Imaging of the CD4-Positive T Lymphocytes in Acute Cardiac RejectionMolecular pharmaceuticsJanuary 1, 0001"Li H, Chen Y, Jin Q, Wu Y, Deng C, Gai Y, Sun Z, Li Y, Wang J, Yang Y, et al."

(11) High fat diet downregulates regulatory T cells in the myocardium of spontaneous hypertensive rats"Nutrition, metabolism, and cardiovascular diseases : NMCD"January 1, 0001"Hong SK, Choo EH, Ihm SH, Chang KY."

(12) Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal LungImmunityJanuary 1, 0001"Wang W, Cohen JA, Wallrapp A, Trieu KG, Barrios J, Shao F, Krishnamoorthy N, Kuchroo VK, Jones MR, Fine A, et al."

(13) Immunological and inflammatory mapping of vascularized composite allograft rejection processes in a rat modelPloS oneJanuary 1, 0001"Friedman O, Carmel N, Sela M, Abu Jabal A, Inbal A, Ben Hamou M, Krelin Y, Gur E, Shani N."

(14) Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon CarcinogenesisCellular and molecular gastroenterology and hepatologyJanuary 1, 0001"Bishehsari F, Engen PA, Voigt RM, Swanson G, Shaikh M, Wilber S, Naqib A, Green SJ, Shetuni B, Forsyth CB, et al."mounting. Immunoperoxidase staining was performed as previously described,28 using 1:400 anti-CD4 (NBP1-19371; Novus Biologicals, Centennial, CO) and 1:500 biotinylated goat anti-rabbit (BA-1000; Vector Laboratories,

(15) Significant involvement of herpesvirus entry mediator in human esophageal squamous cell carcinomaCancerJanuary 1, 0001"Migita K, Sho M, Shimada K, Yasuda S, Yamato I, Takayama T, Matsumoto S, Wakatsuki K, Hotta K, Tanaka T, et al."

(16) An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cellsImmunology lettersJanuary 1, 0001"Hwang I, Ahn G, Park E, Ha D, Song JY, Jee Y."

(17) The effect of programmed cryopreservation on immunogenicity of bladder mucosa in New Zealand rabbitsCryobiologyJanuary 1, 0001"Lu Y, Li B, Wang X, Zheng J, Pu J, Ding Q, Li L, Xu K, Gao P, Chen L."

(18) Trafficking of immune cells across the blood-brain barrier is modulated by neurofibrillary pathology in tauopathiesPloS oneJanuary 1, 0001"Majerova P, Michalicova A, Cente M, Hanes J, Vegh J, Kittel A, Kosikova N, Cigankova V, Mihaljevic S, Jadhav S, et al."

(19) Sex-specific T-cell regulation of angiotensin II-dependent hypertension"Hypertension (Dallas, Tex. : 1979)"January 1, 0001"Ji H, Zheng W, Li X, Liu J, Wu X, Zhang MA, Umans JG, Hay M, Speth RC, Dunn SE, et al."

(20) The Role of Fucoidans Isolated from the Sporophylls of Undaria pinnatifida against Particulate-Matter-Induced Allergic Airway Inflammation: Evidence of the Attenuation of Oxidative Stress and Inflammatory Responses"Molecules (Basel, Switzerland)"January 1, 0001"Herath KHINM, Kim HJ, Kim A, Sook CE, Lee BY, Jee Y."

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CD4 Antibody - BSA Free

CD4 Antibody - BSA Free

CD4 Antibody - BSA Free

CD4 Antibody - BSA Free

CD4 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Questions and Answers

Novus Biologicals, a Bio-Techne Brand

Citations (59)

Reviews

CD4 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

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