JMJD3 Antibody 3457S from Cell Signaling Technology

Product Specs
ItemJMJD3 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number3457S
Quantity100 µl
ApplicationsW
ReactivityH, M
TargetJMJD3
HostRabbit
NCBI Gene AliasesJMJD3, NEDCFSA
NCBI Full Gene Namelysine demethylase 6B
ClonalityPolyclonal
Research AreaChromatin Regulation / Nuclear Function
Molecular Weight200

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
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Website: http://www.cellsignal.com/

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(1) HOXB8 promotes invasion and metastasis of high-grade serous ovarian cancer via suppression of the KDM6B/C/EBPα signaling axisTranslational Cancer ResearchFebruary 28, 2026Li Xiang, Yanqin Lou, Ping Wang, Yajun Hu, Donghua Wanghttps://tcr.amegroups.com/article/view/10.21037/tcr-2025-aw-2272/rc). Methods Materials and reagents Primary antibodies against MMP-2 (4022, 1:1,000), Slug (9585, 1:1,000), KDM6B (3457, 1:1,000), C/EBPα (2843, 1:1,000), H3K27me3 (9733, 1:1,000), and GAPDH (5174, 1:1,000) were purchased

(2) METTL3/RBM15 augments the stability of Kdm6b mRNA and promotes STAT1-mediated macrophage activation and atherosclerosisExperimental & Molecular MedicineDecember 22, 2025Ning Huangfu, Fang Li, Chenqiu Wang, Shouyi Jin, Xiaoya Zheng, Yingsong Wang, Tianxiang Fang, Jiaxi Shen, Yanan Yu, Liguo Jian, et al.anti-phosphorylated STAT1 (p-STAT1, 1:1000, cat. no. 9167, CST), rabbit anti-KDM6B (1:1000, cat. no. 3457, CST), rabbit anti-Jak1 (1:1000, cat. no. 50996, CST), rabbit anti-p-Jak1 (1:1000, cat. no. 74129, CST),

(3) The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal CancerAdvanced ScienceDecember 12, 2025Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, et al.Western blotting detection system (Millipore, USA). The primary antibodies used were as follows: antibodies against KDM6B (#3457), ERK (#4695), p‐ERK (#9102), c‐JUN (#9165), and p‐JUN (#3270) were obtained from Cell Signaling Technology

(4) JMJD3-mediated senescence is required to overcome stress-induced hematopoietic defectsEMBO ReportsJune 25, 2025Yuichiro Nakata, Takeshi Ueda, Yasuyuki Sera, Miho Koizumi, Katsutoshi Imamura, Akinori Kanai, Ken-ichiro Ikeda, Norimasa Yamasaki, Akiko Nagamachi, Kohei Kobatake, et al.,Cell Signaling,Cat#9733 Rabbit anti-FLAG for WB and ChIP,Sigma,Cat#F3165 Rabbit anti-JMJD3 for WB,Cell Signaling,Cat#3457 Rabbit anti-p16INK4a for WB,Cell Signaling,Cat#4824 Rabbit anti-IgG for CUT&RUN,Cell Signaling,Cat#66362 Bacterial

(5) NF-κB-mediated enhancement of H3K27me3 through EZH2: a mechanism to suppress pyocyanin-induced autophagy in macrophagesEur J Med ResApril 29, 2025Ji Wang, Min Bian, Simin Liang, Xiaowei Yi, Yu DuCell Signaling Technology, Cat# 5246; RRID: AB_10694683), NF-κB (1:1000), JMJD3 (1:1000; Cell Signaling Technology, Cat# 3457; RRID: AB_1549620), H3 (1:2000; Cell Signaling Technology, Cat# 4499; RRID: AB_10544537), LC3B (1:2000;

(6) BIX01294 suppresses PDAC growth through inhibition of glutaminase-mediated glutathione dynamicsMolecular metabolismApril 1, 2025Im SS, Seo J, You JE, Bang HW, Kim Y, Kweon J, Kim Y, Shin DM, Son J.caspase-3 (9662), cleaved caspase-3 (9661), PARP (9542), cleaved PARP (9541), KDM6A (33510) and KDM6B (3457) were purchased from Cell Signaling Technology (Beverly, MA, USA). Anti-β-actin antibody (sc-47778)

(7) TGF-β and RAS jointly unmask primed enhancers to drive metastasisCellOctober 31, 2024Jun Ho Lee, Francisco J. Sánchez-Rivera, Lan He, Harihar Basnet, Fei Xavier Chen, Elena Spina, Liangji Li, Carles Torner, Jason E. Chan, Dig Vijay Kumar Yarlagadda, et al.(Bethyl Laboratories, Cat #: A300-109A, 1:1,000), anti-KDM6B antibody (Cell Signaling Technology, Cat #: 3457S, 1:1,000), anti-HMGA2 antibody (Cell Signaling Technology, Cat #: 5269S, 1:1,000), anti-TGFBR2 antibody

(8) Epigenetic Targeting to Overcome Radioresistance in Head and Neck CancerCancersFebruary 9, 2024Schniewind I, Besso MJ, Klicker S, Schwarz FM, Hadiwikarta WW, Richter S, Löck S, Linge A, Krause M, Dubrovska A, et al.overnight: anti-UTX (Cell Signaling, Danvers, MA, USA, #33510S, 1:1000), anti-JMJD3 (Cell Signaling, #3457S 1:1000), anti-Histone H3 (clone: D1H2, Cell Signaling, #4499T, 1:2000), anti-H3K27me3 (Active Motif,

(9) YAP represses intestinal inflammation through epigenetic silencing of JMJD3Clinical EpigeneticsJanuary 20, 2024Hua Zhu, Jiali Lu, MingYue Fu, Ping Chen, Yali Yu, Min Chen, Qiu Zhao, Min Wu, Mei Yeanti-YAP (1:1000, Cell Signaling Technology, 14074), anti-JMJD3 (1:1000, Cell Signaling Technology, 3457), anti-EZH2 (1:1000, Cell Signaling Technology,5246), anti-E-cadherin (1:1000, Cell Signaling Technology,

(10) Macrophage LMO7 deficiency facilitates inflammatory injury via metabolic-epigenetic reprogrammingActa Pharmaceutica Sinica BDecember 1, 2023Shixin Duan, Xinyi Lou, Shiyi Chen, Hongchao Jiang, Dongxin Chen, Rui Yin, Mengkai Li, Yuseng Gou, Wenjuan Zhao, Lei Sun, et al.IκBα (4812), PFKFB3 (D7H4Q), Flag-Tag (14793S), HA-Tag (3724S), Myc-Tag (2272S and 2276S), JMJD3 (#3457) and H3K27me3 (C36B11), were purchased from Cell Signaling Technology. DMEM medium (11965092), RPMI-1640 medium

(11) Epigenetic drug screen identified IOX1 as an inhibitor of Th17-mediated inflammation through targeting TET2EBioMedicineDecember 1, 2022Hu X, Zou Y, Copland DA, Schewitz-Bowers LP, Li Y, Lait PJP, Stimpson M, Zhang Z, Guo S, Liang J, et al.RRID: AB_2799277), anti-TET3 (Cat#ab139311, Abcam, UK), anti-JMJD3 (Cell Signaling Technology Cat# 3457, RRID: AB_1549620), and anti-KDM3A (Proteintech Cat# 12835-1-AP, RRID: AB_1072935) antibodies were purchased

(12) SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockadeNature CommunicationsDecember 1, 2021Octavio A. Romero et al.07-449 (1:1000, Cell Signaling); anti-UTX (KDM6A) D3Q1I (1:1000, Cell Signaling); anti-KDM6B (JMJD3) #3457 (1:1000, Cell Signaling) for western blots or anti-KDM6B (JMJD3) ab38113 (Abcam) for immunostaining

(13) Unlocking the Recovery Potential: JMJD3 Inhibition-Mediated SAPK/JNK Signaling Inactivation Supports Endogenous Oligodendrocyte-Lineage Commitment Post Mammalian Spinal Cord InjuryNeurochemical ResearchApril 1, 2021Zhang Bo-Yin, Zhu Qingsan, Ma Yihang, Yang Fan, Zhu Yuhang, Chang PengyuVital River Laboratory (Beijing, China). Reagents and Antibodies The JMJD3 antibodies were from CST (#3457) and Abcam(ab38113). The #3457 was for immunoblot assay and ab38113 was for IHC staining. The Olig2

(14) KDM6B-mediated histone demethylation of LDHA promotes lung metastasis of osteosarcomaTheranosticsFebruary 6, 2021Yuhang Jiang, Fengfeng Li, Bowen Gao, Mengjun Ma, Meng Chen, Yanfeng Wu, Weidong Zhang, Yangbai Sun, Sanhong Liu, Huiyong ShenAntibodies used in this study were: H3K27me3 (Active Motif, 39155), KDM6B (Cell Signaling Technology, 3457), LDHA (Cell Signaling Technology, 3582), ACTIN (Sigma-Aldrich, A5441). Antibody binding was detected

(15) Interplay of m⁶A and H3K27 trimethylation restrains inflammation during bacterial infectionScience advancesAugust 1, 2020Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, et al.against the following proteins were purchased from Cell Signaling Technology: KDM6B (catalog number 3457), p-IKKα/β (catalog number 2697), p-IκBα (catalog number 9246), IκBα (catalog number 4814), p-p38 (catalog

(16) KSHV ORF59 and PAN RNA Recruit Histone Demethylases to the Viral Chromatin during Lytic ReactivationVirusesApril 9, 2020Hiura K, Strahan R, Uppal T, Prince B, Rossetto CC, Verma SC.Santa Cruz Biotechnology), mouse anti-control IgG (sc-2025, Santa Cruz Biotechnology), rabbit anti-JMJD3 (3457S, Cell Signaling Technology, Danvers, MA, USA), rabbit anti-UTX (33510S, Cell Signaling Technology),

(17) Reactive Extraction of Lactic Acid using Environmentally Benign Green Solvents and Synergistic Mixture of ExtractantsScientia IranicaSeptember 14, 2019Anil Kumar, Avinash Thakurenjoy several pertinent physiochemical characteristics such as renewability, being economical, eco- 3457 friendliness, non-volatility, biodegradability, being nonpolluting, being easy to recoverable, and

(18) The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigmeLifeAugust 29, 2019Thomas Michael Ernst, Anna Evelina Brol, Marcel Gratz, Christoph Ritter, Ulrike Bingel, Marc Schlamann, Stefan Maderwald, Harald H Quick, Christian Josef Merz, Dagmar Timmannleft Crus I (7889), right VI (6404), right V (4250), left Crus II (4223), left V (4085), right Crus I (3457), right I-IV (2761), left I-IV (2529), right VIIIa (2432), right VIIIb (2244), left VIIb (1602), left

(19) USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell LeukemiaClinical cancer research : an official journal of the American Association for Cancer ResearchJanuary 1, 2019Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutierrez-Diaz BT, Wang KK, Johnson MR, Volk AG, Wang F, Wu J, et al.anti-Actin (Millipore, Billerica, MA, clone C4), rabbit anti-JMJD3 (Cell Signaling Technology, Danvers, MA, #3457), rabbit anti-USP7 (Bethyl Laboratories, Montgomery, TX, #A300–033A-7), rabbit anti-Cleaved NOTCH1 (Val1744)

(20) Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapyNature MedicineJune 1, 2018Lu Wang et al.(#5246S), UTX (#33510), H3K27me3 (#9733), H3K27ac (#8173), H2AK119ub (#8240), H2A (#12349) and JMJD3 (#3457S) antibodies were purchased from Cell Signaling. HSP90 (sc-7947) was purchased from Santa Cruz, M2 Flag

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JMJD3 Antibody

JMJD3 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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JMJD3 Antibody from Cell Signaling Technology

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