The Mouse Anti-Human Podocalyxin Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PCLP1, Podocalyxin, podocalyxin like, and PODXL. This antibody recognizes Human antigen. The Mouse Anti-Human Podocalyxin Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface