The HIF1 alpha Polyclonal Antibody from MyBioSource.com is a Goat Polyclonal antibody to HIF1 alpha. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Non-Human Primate, Porcine, Rabbit, and Sheep antigen. The HIF1 alpha Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease