Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody ab75745 from Abcam

Product Specs
ItemAnti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab75745
Antibody TypePrimary
Conjugate/TagUnconjugated
HostRabbit
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
ClonalityPolyclonal
Quantity100 UL
IsotypeIgG
Formatab75745 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site
Concentration1 mg/ml
ModificationsPhospho-Y279
Research AreaImmuno-oncology
Gene NameGSK3A
ReactivityHuman
TargetGSK3 beta

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer''s diseaseNature communicationsOctober 21, 2023Zhang X, Tang L, Yang J, Meng L, Chen J, Zhou L, Wang J, Xiong M, Zhang Z.detection. Reagents Anti-p-tau S202 (ab108387, 1:1000), p-tau S396 (ab109390, 1:1000), p-GSK3β Y216 (ab75745, 1:1000), GSK3β (ab32391, 1:1000), and p-RhoA S188 (ab41435, 1:500) were purchased from Abcam (Cambridge,

(2) Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/βFrontiers in immunologyJanuary 1, 2023Park JH, Hwang JW, Lee HJ, Jang GM, Jeong YJ, Cho J, Seo J, Hoe HS.,Cell Signaling,#12885,ICC p-Tau (Ser396),Mouse,1:200,Cell Signaling,#9632,ICC p-GSK3α/β,Rabbit,1:200-1:1000,Abcam,Ab75745,IF/WB DYRK1A,Rabbit,1:200,Abcam,Ab180910,IF β-actin,mouse,1:5000,Santa Cruz,SC-47778,WB Secondary

(3) Targeting the interaction of GABA(B) receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse brain cells and slicesBrain pathology (Zurich, Switzerland)January 1, 2023Balakrishnan K, Hleihil M, Bhat MA, Ganley RP, Vaas M, Klohs J, Zeilhofer HU, Benke D.#ab93926), rabbit pGSK3β‐S9 (1:1500 for IF, Abcam #ab131097), rabbit pGSK3β‐Y216 (1:1500 for IF, Abcam #ab75745), rabbit ubiquitin K63‐specific (clone Apu3, 1:50 for PLA; Millipore #05‐1308), rabbit NeuN (1:400 for

(4) Effects of electroacupuncture on the functionality of NG2-expressing cells in perilesional brain tissue of mice following ischemic strokeNeural regeneration researchJuly 1, 2022Lee HJ, Jung DH, Kim NK, Shin HK, Choi BT.beta (GSK3β, 1:500; Cat# ab93926, Abcam), and rabbitanti-phosphorylated GSK3β (pGSK3β; 1:500, Cat# ab75745, Abcam). The tissue was washed in PBS and incubated in a fluorescent-conjugated goat anti-mouse IgG

(5) lncRNA DHFRL1‑4 knockdown attenuates cerebral ischemia/reperfusion injury by upregulating the levels of angiogenesis‑related genesInternational Journal of Molecular MedicineJune 22, 2022Yu Zhou, Dezhi Huang, Yang Cai, Ming Wang, Wenjia Ma, Zhongzhong Jiang, Min Liuglycogen synthase kinase-3β (GSK-3β; cat. no. ab32391, 1/1,000), phosphorylated (p-)GSK-3β (cat. no. ab75745, 1/1,000), glyceraldehyde-3-phosphate dehydrogenase (GAPDH; cat. no. ab8245, 1/1,000) and horseradish

(6) SERP1 reduces inchoate acute hepatic injury through regulation of endoplasmic reticulum stress via the GSK3β/β‑catenin/TCF/LEF signaling pathwayMolecular Medicine ReportsApril 6, 2022Jie Cai, Zhenhua Sun, Lili Zhang, Hongrui Xucode ab180799; 1:1,000), GSK3β (cat. no. ab227208; 1:1,000), phosphorylated (p-)GSK3β (product code ab75745; 1:1,000), β-catenin (product code ab32572; 1:5,000), Bcl-2 (product code ab196495; 1:1,000), Bad (product

(7) Lamin B1 is a potential therapeutic target and prognostic biomarker for hepatocellular carcinomaBioengineeredApril 1, 2022Yang Y, Gao L, Chen J, Xiao W, Liu R, Kan H.Abcam, ab93926), Phospho-Akt (p-Akt) (1: 2000, CST, #4060), Phospho-GSK-3β (p-GSK-3β) (1: 1000, Abcam, ab75745) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (1: 10000, Abcam, ab8245) were used for this assay.

(8) Luteolin Ameliorates Methamphetamine-Induced Podocyte Pathology by Inhibiting Tau Phosphorylation in MiceEvidence-Based Complementary and Alternative MedicineMarch 24, 2022Jiuyang Ding, Yuanhe Wang, Zhuo Wang, Shanshan Hu, Zhu Li, Cuiyun Le, Jian Huang, Xiang Xu, Jiang Huang, Pingming Qiudilution Antibody,Host,Distributor,IHC,WB p-Tau (ser396),Rabbit,"Abcam, ab109390",1:300,1:1000 p-GSK3β Y216,Rabbit,"Abcam, ab75745",1:500,1:2000 Podocalyxin-like protein 1,Mice,"Santa Cruz, sc23903",1:200,1:1000 Synaptopodin,Rabbit,"Abcam,

(9) Propofol suppresses adipose-derived stem cell progression via PI3K/AKT-Wnt signaling pathwayBMC anesthesiologyMarch 9, 2022Yin G, Wang J, Zhong Y, Wu W.ab179463), p-AKT (1:500, Abcam, ab38449), Wnt3a, GSK3β (1:1000, Abcam, ab93926), p-GSK3β (1:500, Abcam, ab75745), β-catenin (1:400, Abcam, ab224803, p-β-catenin (1:500, Abcam, ab757777), cyclinD1 (1:10000, Abcam,

(10) Renoprotective Effect of Liraglutide Is Mediated via the Inhibition of TGF-Beta 1 in an LLC-PK1 Cell Model of Diabetic NephropathyCurrent issues in molecular biologyFebruary 25, 2022Ninčević V, Zjalić M, Kolarić TO, Smolić M, Kizivat T, Kuna L, Včev A, Tabll A, Ćurčić IB.216 + GSK3 alpha—phosphorylated on tyrosine 279,IgG polyclonal,Rabbit,"Abcam, Cambridge, UK Cat. No. ab75745",1:2000 SOCS3,Anti-suppressor of cytokine signaling-3,IgG,Mouse,"Abcam, Cambridge, UK Cat. No. ab14939",1:1000 pSTAT3,Anti-signal

(11) Bilateral Meningioma: A Case Report and Review of the LiteratureInternational Journal of Molecular SciencesJanuary 21, 2022Anja Bukovac, Hana Panić, Tomislava Mrgan, Nika Šlaus, Anja Kafka, Niko Njirić, Nives Pećina-ŠlausM3539 (Dako, Santa Clara, CA, USA)",Monoclonal,1:200 GSK3beta (active),"Anti-GSK3β (phospho Y216) ab75745 (Abcam, Cambridge, MA, USA)",Polyclonal,1:100 GSK3beta (inactive),"Anti-GSK3β (phospho S9) ab131097

(12) Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling PathwaysFrontiers in pharmacologyJanuary 1, 2022Shi YL, Zhang YP, Luo H, Xu F, Gao JM, Shi JS, Gong QH.(ab5599), Akt (ab179463), p-Akt (ab131443), glycogen synthase kinase (GSK)-3β (ab93926), p-GSK-3βTyr 216 (ab75745), p-GSK-3β Ser 9 (ab131097), GLUT-2 (ab54460), β-tubulin (ab179513), and proliferating cell nuclear

(13) Inhibiting EGFR/HER-2 ameliorates neuroinflammatory responses and the early stage of tau pathology through DYRK1AFrontiers in immunologyJanuary 1, 2022Kim J, Kim SJ, Jeong HR, Park JH, Moon M, Hoe HS.no. Iba-1,Rabbit,1:500,Wako,019-19741 GFAP,chicken,1:500,Millipore,AB5541 NLRP3,Goat,1:500,Novus,NBP2-12446 IL-1β,Rabbit,1:100,Abcam,AB9722 AT100,Mouse,1:200,Invitrogen,mn1020 AT180,Mouse,1:200,Invitrogen,mn1040 DYRK1A,Rabbit,1:200,Abcam,ab180910 p-CDK5,Rabbit,1:200,MyBioSource,MBS9601140 p-GSK3β,Rabbit,1:200,Abcam,ab75745 List of primary antibodies used for IF.

(14) Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 PathwayMoleculesDecember 16, 2021Rania Alaaeldin, Iman A. M. Abdel-Rahman, Heba Ali Hassan, Nancy Youssef, Ahmed E. Allam, Sayed F. Abdelwahab, Qing-Li Zhao, Moustafa Fathyphosphorylated Akt (ph-Akt; #ab38449, Abcam), total Akt (Akt) (#ab188099, Abcam), phosphorylated GSK3 (ph-GSK3; #ab75745, Abcam), total GSK3 (#ab131356, Abcam), phosphorylated FoxO1 (ph-FoxO1; #ab131339, Abcam), and total

(15) Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancerScientific ReportsDecember 1, 2021Yuanyuan Fu, Dionyssios Katsaros, Nicoletta Biglia, Zhanwei Wang, Ian Pagano, Marcus Tius, Maarit Tiirikainen, Charles Rosser, Haining Yang, Herbert YuCell Signaling Technology), anti-cMYC (#18583 from Cell Signaling Technology), anti-p-GSK3β(Y216) (ab75745 from Abcam), anti-GSK3β (#12456 from Cell Signaling Technology, and anti-β-actin (A2228 from Sigma-Aldrich)

(16) Small-molecule HDAC and Akt inhibitors suppress tumor growth and enhance immunotherapy in multiple myelomaJournal of Experimental & Clinical Cancer ResearchDecember 1, 2021Mitsuhito Hirano et al.dilution of GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) rabbit polyclonal antibody (Abcam, ab75745, Cambridge, UK), a 1:100 dilution of c-Myc rabbit monoclonal antibody (clone Y69, Abcam, ab32072) for

(17) CBX2 Induces Glioma Cell Proliferation and Invasion Through the Akt/PI3K PathwayTechnology in Cancer Research & TreatmentOctober 28, 2021Le Wang, Bingcheng Ren, Hao Zhuang, Yue Zhong, Yang Nanantibody for CBX2 (cat. no. ab235305, dilution ratio1:1000 for Western Blot) and for p-GSK-3β (cat. no. ab75745, dilution ratio1:1000 for Western Blot) were purchased from Abcam. Primary antibodies for N-cadherin

(18) Idebenone Decreases Aβ Pathology by Modulating RAGE/Caspase-3 Signaling and the Aβ Degradation Enzyme NEP in a Mouse Model of ADBiologySeptember 19, 2021Lee HJ, Jeong HR, Park JH, Hoe HS.,Cell Signaling,9664 NEP,Rabbit,1:200,Millipore,AB5458 IDE,Rabbit,1:200,Abcam,AB32216 ADAM17,Rabbit,1:100,Abcam,AB2051 ADAM10,Rabbit,1:100,Abcam,AB1997 AT180,Mouse,1:100,Invitrogen,MN1040 Tau5,Mouse,1:100,Invitrogen,AHB0042 p-GSK-3βY216,Rabbit,1:200,Abcam,AB75745 p-CDK-5,Rabbit,1:200,LSBio,LS-C354604 DYRK1A,Rabbit,1:200,Abcam,AB69811 Primary antibodies.

(19) ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/β-Catenin SignalingMolecular cancer research : MCRSeptember 1, 2021Xu C, Li YM, Sun B, Zhong FJ, Yang LY.(9315); MMP16, Abcam (ab73877); MMP7, Cell Signaling Technology (71031); p-GSK3-β (Tyr216), Abcam (ab75745); p-β-catenin (Ser33/37/Thr41), Cell Signaling Technology (9561); RGS4, Abcam (ab97307); RGS5, LifeSpan BioSciences

(20) A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cellsNature communicationsAugust 13, 2021Dagg RA, Zonderland G, Lombardi EP, Rossetti GG, Groelly FJ, Barroso S, Tacconi EMC, Wright B, Lockstone H, Aguilera A, et al.Cell Signaling, 2341), GSK3α/β (1:1000, Cell Signaling, 5676S), phosphorylated Y279/Y216 GSK3α/β (1:1000, Abcam, AB75745), cleaved PARP [Asp214] [D64E10] (1:1000, Cell Signaling, 5625S), PARP [46D11] (1:1000, Cell Signaling,

Write a Review

(1)

6/22/2016Good anti-pGSK3 beta Antibody Raj KumarHuman aortic endothelial cells were subjected to growth factor treatment for various time points and tested for its effect on phospho GDK3 beta levels. After resolving proteins from each treatment in ... Read Review

Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody from Abcam

Abcam

Citations (126)

Reviews

Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map