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Antibodies
Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody
Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody from Abcam
(1)
Write a review
Citations:
(126)
Supplier Page
Supplier Page from
Abcam for
Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab75745
Antibody Type
Primary
Conjugate/Tag
Unconjugated
Host
Rabbit
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Clonality
Polyclonal
Quantity
100 UL
Isotype
IgG
Format
ab75745 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site
Concentration
1 mg/ml
Modifications
Phospho-Y279
Research Area
Immuno-oncology
Gene Name
GSK3A
Reactivity
Human
Target
GSK3 beta
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (126)
(81)
hnRNP K plays a protective role in TNF-α-induced apoptosis in podocytes
Bioscience reports
June 29, 2018
Zhao S, Feng J, Wang Q, Tian L, Zhang Y, Li H.
ERK (
Abcam
,
ab17942
), Casapse 3 (CST. sc-271759), Caspase 8 (catalog no. sc-6136), p-GSK3β (
Abcam
,
ab75745
), p-ERK (
Abcam
,
ab50011
), and GAPDH (
Abcam
,
ab181602
) at 4◦ C overnight. After three washes with TBST,
(82)
Effects of isoliquiritigenin on ovarian cancer cells
OncoTargets and Therapy
April 3, 2018
Nan Li, Liang Yang, Xinna Deng, Yanan Sun
(Cat#ab32505), anti-
mTOR
(Cat#
ab2732
), anti-p-mTOR (Cat#
ab131538
), anti-p-ERK (Cat#
ab214362
), anti-GSK3β (Cat #
ab75745
), anti-P70/ S6K (Cat#
ab32529
),
anti-Cyclin
D1 (Cat#
ab40754
), and anti-WNT3a (Cat#
ab28472
), were purchased
(83)
Vildagliptin, a DPP4 inhibitor, alleviates diabetes‑associated cognitive deficits by decreasing the levels of apoptosis‑related proteins in the rat hippocampus
Experimental and Therapeutic Medicine
April 2, 2018
Dan‑Dan Zhang, Nan Shi, Hui Fang, Liang Ma, Wei‑Ping Wu, Ya‑Zhong Zhang, Jin‑Li Tian, Luo‑Bing Tian, Kang Kang, Si Chen
(
1:1,000
; cat. no.
AB8805
;
Abcam
), GSK3β (
1:1,000
; cat. no.
AB32391
;
Abcam
) and p‑GSK3β (
1:1,000
; cat. no.
AB75745
;
Abcam
), brain‑derived neurotrophic factor (BDNF;
1:1,000
, cat. no.
AB226843
;
Abcam
), NGF (
1:1,000
,
(84)
Anthelmintic pyrvinium pamoate blocks Wnt/β-catenin and induces apoptosis in multiple myeloma cells
Oncology letters
April 1, 2018
Xu F, Zhu Y, Lu Y, Yu Z, Zhong J, Li Y, Pan J.
Molecular Probes
(Thermo Fisher Scientific, Inc.). Antibody phospho‑GSK3β (Y216,
1:1,000
; cat. no.
ab75745
) was purchased from
Abcam
(Cambridge, UK), IRDye® 800CW goat anti‑mouse IgG (H+L) (
1:10,000
; cat. no.
(85)
MicroRNA-133b inhibits cell proliferation and promotes apoptosis by targeting cullin 4B in esophageal squamous cell carcinoma
Experimental and Therapeutic Medicine
February 28, 2018
Hairong Huang, Yang Xu, Zhong Guo, Xi Chen, Shaiguang Ji, Zhiyun Xu
9315
;
1:1,000
;
Cell Signaling Technology
, Danvars, MA, USA), phosphorylated (p)-GSK-3βTyr216 (cat. no.
ab75745
;
1:1,000
;
Abcam
) and β-actin (cat. no.
sc-130656
;
1:1,000
;
Santa Cruz Biotechnology, Inc
., Dallas, TX,
(86)
RP105 protects PC12 cells from oxygen‑glucose deprivation/reoxygenation injury via activation of the PI3K/AKT signaling pathway
International Journal of Molecular Medicine
February 12, 2018
Yanpeng Sun, Lu Liu, Jiang Yuan, Qiang Sun, Na Wang, Yunfu Wang
no.
9272
), p‑glycogen synthase kinase 3β (
1:2,000
dilution; p‑GSK‑3β; Abcam, Cambridge, UK; cat. no.
ab75745
), GSK‑3β (
1:2,000
dilution;
Abcam
; cat. no.
ab93926
), cleaved caspase‑9 (
1:500
dilution; Abscitech,
(87)
Itraconazole attenuates hepatic gluconeogenesis and promotes glucose uptake by regulating AMPK pathway
Experimental and therapeutic medicine
February 1, 2018
Na RS, Ma C, Liu QR, Wu LM, Zheng XL, Liu ZW.
(phospho S487) (
ab131357
), GSK3β (
ab32391
) (all diluted at
1:5,000
;
Abcam
, Cambridge, MA, USA), p‑GSK3β (
ab75745
), PGC‑1α (
ab54481
) (both diluted at
1:1,000
;
Abcam
),
PEPCK
(
sc‑377027
) (diluted at
1:100
;
Santa Cruz Biotechnology, Inc
(88)
TAAR1 induces a disturbed GSK3β phosphorylation in recurrent miscarriages through the ODC
Endocrine Connections
February 1, 2018
Stavroula Stavrou et al.
(89)
LncRNA GAS5 Represses Osteosarcoma Cells Growth and Metastasis via Sponging MiR-203a
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
January 1, 2018
Wang Y, Kong D.
(p-AKT,
ab38449
),
Glycogen
synthesis kinase 3 beta (GSK3β,
ab32391
), phosphorylated GSK3β (p-GSK3β,
ab75745
) and GAPDH (
ab8245
) (
Abcam
, USA). Then the
membranes
were washed and incubated with secondary antibodies
(90)
Impacts of Acute Hypoxia on Alzheimer's Disease-Like Pathologies in APP
swe
/PS1
dE9
Mice and Their Wild Type Littermates
Frontiers in neuroscience
January 1, 2018
Zhang F, Zhong R, Qi H, Li S, Cheng C, Liu X, Liu Y, Le W.
Anti-GSK3β Antibody (Y174) (
ab32391
,
1:5,000
;
Abcam
, Cambridge, UK); Anti-GSK3β (phospho Y216) Antibody (
ab75745
,
1:1,000
;
Abcam
, Cambridge, UK);
Microtubule
-associated Protein 1A/1B-light Chain 3B (
LC3B
) Antibody
(91)
Treatment with placental growth factor attenuates myocardial ischemia/reperfusion injury
PloS one
January 1, 2018
Zhang Y, Cao C, Xin J, Lv P, Chen D, Li S, Yang H, Chen C, Liu B, Li Q.
(
R&D Systems
,
AF4170
),
VEGFR1
(
Abcam
,
ab32152
), p-AKT (
Abcam
,
ab81283
), AKT (
Abcam
,
ab32505
), p-GSK3β (
Abcam
,
ab75745
), GSK3β (
Abcam
,
ab32391
), p-FOXO3a (
Abcam
,
ab47285
),
FOXO3a
(
Abcam
,
ab109629
) and Cleaved
Caspase-3
(92)
GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents
Oncotarget
December 29, 2017
Reem Karmali, Vineela Chukkapalli, Leo I. Gordon, Jeffrey A. Borgia, Andrey Ugolkov, Andrew P. Mazar, Francis J. Giles
Rabbit anti-GSK-3β (
Cell Signaling
, Cat. No:
12456
), Rabbit anti-phospho-GSK-3β (Y216) (
Abcam
, Cat. No:
ab75745
), Rabbit anti-c-MYC (
Cell Signaling
, Cat. No:
5605
), Rabbit anti-phospho-c-MYC (Ser 62) (
Cell Signaling
,
(93)
Influence of sevoflurane exposure on mitogen-activated protein kinases and Akt/GSK-3β/CRMP-2 signaling pathways in the developing rat brain
Experimental and Therapeutic Medicine
December 18, 2017
Yafang Liu, Chuiliang Liu, Minting Zeng, Xue Han, Kun Zhang, Yanni Fu, Jue Li, Yujuan Li
1:2,000
dilution (all
Cell Signaling Technology
, Inc., Danvers, MA, USA) and anti‑p‑GSK‑3β (Ty 216) (cat no.
ab75745
;
Abcam
, Cambridge, USA) at
1:2,000
dilution. The
membranes
were washed with TBST three times and incubated
(94)
Ursolic acid inhibits breast cancer growth by inhibiting proliferation, inducing autophagy and apoptosis, and suppressing inflammatory responses via the PI3K/AKT and NF-κB signaling pathways in vitro
Experimental and Therapeutic Medicine
October 1, 2017
Juan Luo, Yan-Ling Hu, Hong Wang
UK), phosphorylated (p)-AKT (
1:1,000
;
ab38449
;
Abcam
), AKT (
1:1,000
;
ab8805
;
Abcam
), p-GSK3β (
1:1,000
;
ab75745
;
Abcam
), GSK3β (
1:1,000
;
ab32391
;
Abcam
), cyclin-D1 (
1:1,000
;
ab16663
;
Abcam
), Bcl-2 (
1:1,000
;
ab59348
;
(95)
Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway
International Journal of Molecular Medicine
October 1, 2017
Yizhi Zhang, Dejun Sun, Qingjin Meng, Wanxu Guo, Qiuhui Chen, Ying Zhang
Merck Millipore
, Darmstadt, Germany), total (t)-
AKT
(
ab126811
) and p-glycogen synthase kinase-3β (GSK-3β) (
ab75745
) (both from
Abcam
, Cambrige, UK), T-GSK-3β (PK1111) and glyceraldehyde 3-phosphate dehydrogenase (GAPDH)
(96)
ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury
Scientific reports
September 12, 2017
Cao J, Gaamouch FE, Meabon JS, Meeker KD, Zhu L, Zhong MB, Bendik J, Elder G, Jing P, Xia J,
et al
.
(97)
P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo
Cell Death & Disease
June 1, 2017
Chao Gu, Yan Zhang, Qingsong Hu, Jiayuan Wu, Haigang Ren, Chun-Feng Liu, Guanghui Wang
(98)
Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats
Cellular Physiology and Biochemistry
May 12, 2017
Keyan Chen, Nan Wang, Yugang Diao, Wanwei Dong, YingJie Sun, Lidan Liu, Xiuying Wu
by
incubation
with
Akt
(
ab179463
,
Abcam
, USA), p-Akt (
ab131443
,
Abcam
), GSK3β (
ab93926
,
Abcam
), or p-GSK3β (
ab75745
,
Abcam
) antibodies at 37°C for 1 h. The slices were then washed 3 times with 0.02 M PBS (2 min per wash).
(99)
Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells
Archives of toxicology
May 1, 2017
Li CH, Liu CW, Tsai CH, Peng YJ, Yang YH, Liao PL, Lee CC, Cheng YW, Kang JJ.
(100)
Icariside II , a novel phosphodiesterase 5 inhibitor, protects against H
2
O
2
‐induced PC 12 cells death by inhibiting mitochondria‐mediated autophagy
Journal of Cellular and Molecular Medicine
February 1, 2017
Jianmei Gao, Yuanyuan Deng, Caixia Yin, Yuangui Liu, Wei Zhang, Jingshan Shi, Qihai Gong
(
ab56416
), anti‐HSP60 (
ab46798
), anti‐GSK‐3β (
ab93926
), anti‐p‐ser9‐GSK‐3β (
ab75814
), anti‐p‐tyr216‐GSK‐3β (
ab75745
) were purchased from
Abcam
(Cambridge, UK).
Cell culture
and treatment The highly differentiated
rat
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Reviews
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(1)
6/22/2016
Good anti-pGSK3 beta Antibody
Raj Kumar
Human aortic endothelial cells were subjected to growth factor treatment for various time points and tested for its effect on phospho GDK3 beta levels. After resolving proteins from each treatment in ...
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Anti-GSK3 beta (phospho Y216) + GSK3 alpha (phospho Y279) antibody from Abcam
Supplier Page
View Company Product Page
Product Specs
Company Info
Citations
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