Supplier Page from Novus Biologicals, a Bio-Techne Brand for Lambda Light Chain Antibody (SPM559) [Alexa Fluor® 488]
Available conjugates: Available conjugates: Janelia Fluor 525, Alexa Fluor 350, DyLight 755, mFluor Violet 500 SE, mFluor Violet 610 SE, HRP, mFluor Violet 450 SE, Allophycocyanin, Alexa Fluor 488, DyLight 550, Alexa Fluor 594, Alexa Fluor 405, DyLight 488, DyLight 650, Alexa Fluor 750, Janelia Fluor 646Specificity: This monoclonal antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Sizes Available: 0.1 ml