NCAM-1/CD56 Antibody (SPM489) [Alexa Fluor® 405] from Novus Biologicals, a Bio-Techne Brand

Available conjugates: Available conjugates: CoraFluor 1, Alexa Fluor 350, Janelia Fluor 669, Alexa Fluor 647, DyLight 680, HRP, mFluor Violet 450 SE, Allophycocyanin, Alexa Fluor 488, DyLight 550, PE, Alexa Fluor 594, PerCP, Alexa Fluor 405, Alexa Fluor 532, DyLight 755, Alexa Fluor 750, Biotin

Specificity: This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Sizes Available: 0.1 ml