Jackson ImmunoResearch Laboratories, Inc.'s AffiniPure™ F(ab')2 fragment Rabbit Anti-Human IgG (H+L) is a Rabbit Polyclonal antibody. The AffiniPure™ F(ab')2 fragment Rabbit Anti-Human IgG (H+L) Antibody was generated using IgG as the antigen and it reacts with Homo Sapiens, and Human.
Description
Based on immunoelectrophoresis and/or ELISA, the antibody reacts with whole molecule human IgG. It also reacts with the light chains of other human immunoglobulins. No antibody was detected against non-immunoglobulin serum proteins. The antibody may cross-react with immunoglobulins from other species. F(ab')2 fragment antibodies are generated by pepsin digestion of whole IgG antibodies to remove most of the Fc region while leaving some of the hinge region. F(ab')2 fragments have two antigen-binding Fab portions linked together by disulfide bonds and therefore they are divalent. The average molecular weight is about 110 kDa. They are used for specific applications, such as to avoid binding of secondary antibodies to live cells with Fc receptors or to Protein A or Protein G