AP-2 gamma Antibody AF5059 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemAP-2 gamma Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF5059
NCBI Gene AliaseshAP-2g, ERF1, AP2-GAMMA, TFAP2G
ApplicationsImmunohistochemistry,Western Blot,Immunofluorescence,Immunocytochemistry
Quantity100 ug (also 25 ug)
ReactivityHuman,Mouse
TargetAP-2 gamma
Conjugate/TagUnconjugated
HostGoat
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
NCBI Full Gene Nametranscription factor AP-2 gamma
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human AP-2 gamma, Leu128-Val223, Accession # Q92754
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human AP-2 gamma in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) AP-2 alpha is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Driving Naive State Induction Using Human Wharton Jelly-Mesenchymal Stem Cell-Derived Conditioned Medium in Rhesus Monkey Embryonic Stem CellsCellsMarch 31, 2026Preeyanan Anwised, Ratree Moorawong, Worawalan Samruan, Jittanun Srisutush, Sirilak Somredngan, Irene Aksoy, Pierre Savatier, Rangsun Parnpai(Danvers, MA, USA) #81694S" Primary Ab,Goat anti-TFAP2C,1:50,"R&D Systems (Minneapolis, MN, USA) #AF5059" Primary Ab,Rabbit anti-KLF17,1:200,"Sigma-Aldrich (St. Louis, MO, USA) #HPA024629" Primary Ab,Sheep

(2) Efficient stem cell-derived mouse embryo models for environmental studiesDevelopmental CellJanuary 14, 2026Victoria Jorgensen, Min Bao, Sergi Junyent, Christoph M. Häfelfinger, Laura Amaya, Zhaodi Liao, Brian A. Williams, Dong-Yuan Chen, Amanda Wu, Matt Thomson, et al.LAMININ (Millipore, L9393), RXRA (abcam, ab125001), KRT18 (abcam, ab668), TFAP2C (AP2g, R&D systems, AF5059), SOX2 (R&D systems, AF2018). Images were acquired with an inverted Leica SP8 confocal microscope (Leica

(3) Molecular and cellular dynamics of the developing human neocortexNatureNovember 6, 2025Li Wang, Cheng Wang, Juan A. Moriano, Songcang Chen, Guolong Zuo, Arantxa Cebrián-Silla, Shaobo Zhang, Tanzila Mukhtar, Shaohui Wang, Mengyi Song, et al.(Oxford Instruments) and ImageJ v.1.5462. The following antibodies were used: TFAP2C (R&D systems, AF5059, 1:50), CRYAB (Abcam, ab13496, 1:200), OLIG2 (Abcam, ab109186, 1:150), EGFR (Abcam, ab231, 1:200), SPARCL1

(4) PAX6-dependent differentiation landscape of ocular surface epithelium via single-cell RNA sequencing in hiPSC-derived ocular developmental organoidCommun BiolAugust 14, 2025Rei Kamuro, Masahito Yoshihara, Susumu Hara, Takahiro Nemoto, Laura Howard, Ai Honda, Ayano Yamamoto, Toru Takigawa, Susumu Sakimoto, Koichi Baba, et al.,Cell Signaling Technology,2840,AB_2167691 TRA-1-60(S),Mouse,Monoclonal,TRA-1-60(S),Cell Signaling Technology,4746,AB_2119059 TFAP2C,Goat,Polyclonal,–,R&D Systems,AF5059,AB_2255891a MSX2,Mouse,Monoclonal,786607,R&D Systems,MAB7917,AB_3096365 GATA3,Goat,Polyclonal,–,R&D Systems

(5) Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programmingCell Stem CellJune 5, 2025Gerrald A. Lodewijk, Sayaka Kozuki, Clara J. Han, Benjamin R. Topacio, Seungho Lee, Lily Nixon, Abolfazl Zargari, Gavin Knight, Randolph Ashton, Lei S. Qi, et al.anti-Gata3,Cell Signaling Technology,Cat#5852; RRID: AB_10835690 Goat polyclonal anti-Tfap2c,R&D Systems,Cat#AF5059; RRID: AB_2255891 Mouse monoclonal anti-Foxa1,Abcam,Cat#ab55178; RRID: AB_941631 Goat polyclonal anti-Sox17,R&D Systems

(6) Interpreting regulatory mechanisms of Hippo signaling through a deep learning sequence modelCell GenomApril 9, 2025Khyati Dalal, Charles McAnany, Melanie Weilert, Mary Cathleen McKinney, Sabrina Krueger, Julia ZeitlingerProtein G Dynabeads (Invitrogen). The following antibodies were used: anti-TFAP2C (R & D systems, no. AF5059), anti-TEAD4 (Abcam, no. ab58310), anti-CDX2 (Bethyl Laboratories, no. A300-692A), anti-GATA3 (Cell Signaling

(7) Molecular and cellular dynamics of the developing human neocortex at single-cell resolutionbioRxiv : the preprint server for biologyAugust 4, 2024Wang L, Wang C, Moriano JA, Chen S, Zuo G, Cebrián-Silla A, Zhang S, Mukhtar T, Wang S, Song M, et al.

(8) Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editingbioRxivMarch 10, 2024Gerrald A. Lodewijk, Sayaka Kozuki, Clara Han, Benjamin R. Topacio, Abolfazl Zargari, Seungho Lee, Gavin Knight, Randolph Ashton, Lei S. Qi, S. Ali Shariati5851S",1:2000 Rabbit anti Gata3,"Cell Signaling Technology, 5852S",1:1000 Goat anti Tfap2c,"R&D Systems, AF5059",1:1000 Mouse anti Foxa1,"Abcam, ab55178",1:2000 Goat anti Sox17,"R&D Systems, AF1924",1:2000 Goat

(9) Distinct pathways drive anterior hypoblast specification in the implanting human embryoNature cell biologyMarch 1, 2024Weatherbee BAT, Weberling A, Gantner CW, Iwamoto-Stohl LK, Barnikel Z, Barrie A, Campbell A, Cunningham P, Drezet C, Efstathiou P, et al.anti GATA4 (14-9980-82, Thermo Fisher Scientific; 1:500 dilution), goat polyclonal anti AP2-gamma (AF5059, R&D Systems; 1:500 dilution), goat polyclonal anti Otx2 (AF1979, R&D Systems; 1:1,000 dilution) and

(10) Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitroNature protocolsDecember 1, 2023Lau KYC, Amadei G, Zernicka-Goetz M.Marker,Spatial expression,Antibody,Dilution used Ap2γ,ExE,"R&D Systems, cat. no. AF5059(RRID: AB_2255891, https://scicrunch.org/resolver/RRID:AB_2255891)",1:500 Brachyury,Primitive streak,"R&D Systems

(11) Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tensionNature cell biologySeptember 1, 2022Bao M, Cornwall-Scoones J, Sanchez-Vasquez E, Chen DY, De Jonghe J, Shadkhoo S, Hollfelder F, Thomson M, Glover DM, Zernicka-Goetz M.optical plates before confocal imaging. The following primary antibodies were used: Tfap2c (1:200; AF5059; R&D Systems), Brachyury (1:200; AF2085; R&D Systems), Gata4 (1:500; 36966; Cell Signalling Technology),

(12) Spatial profiling of early primate gastrulation in uteroNatureSeptember 1, 2022Bergmann S, Penfold CA, Slatery E, Siriwardena D, Drummer C, Clark S, Strawbridge SE, Kishimoto K, Vickers A, Tewary M, et al.

(13) An integrated atlas of human placental development delineates essential regulators of trophoblast stem cellsDevelopment (Cambridge, England)July 1, 2022Chen Y, Siriwardena D, Penfold C, Pavlinek A, Boroviak TE.Samples were incubated with primary antibodies in blocking solution overnight at 4°C. AP-2γ (Biotechne, AF5059, 1:250), HLA-G (Bio-Rad, MCA2043, 1:250), hCG (Abcam, ab53087, 1:250), GATA3 (Cell Signaling Technology,

(14) Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In VitroDevelopmental cellFebruary 8, 2021Amadei G, Lau KYC, De Jonghe J, Gantner CW, Sozen B, Chan C, Zhu M, Kyprianou C, Hollfelder F, Zernicka-Goetz M.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Goat polyclonal anti-AP-2 gamma,R&D Systems,Cat# AF5059; RRID: AB_2255891 Mouse monoclonal anti-AP-2 gamma,Santa Cruz Biotechnology,Cat# sc-12762; RRID: AB_667770 Goat

(15) Basement membrane remodelling regulates mouse embryogenesisNatureJune 1, 2020Kyprianou C, Christodoulou N, Hamilton RS, Nahaboo W, Boomgaard DS, Amadei G, Migeotte I, Zernicka-Goetz M.(D175) (5A1E) (1:200; Cell Signaling Technologies, 9664S; lot: 21) hAP-2gamma (1:200; R&D Systems, AF5059; lot: CBHR011904A and CBHR0219051) Eukaryotic cell lines Policy information about cell lines Cell line

(16) Self-Organization of Mouse Stem Cells into an Extended Potential BlastoidDevelopmental cellDecember 16, 2019Sozen B, Cox AL, De Jonghe J, Bao M, Hollfelder F, Glover DM, Zernicka-Goetz M.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Goat anti- AP-2 gamma Polyclonal,R&D systems,Cat# AF5059; RRID:AB_2255891 Mouse Anti-Cdx2 Monoclonal,BioGenex,Cat# MU392-UC; RRID:AB_2335627 Rabbit Anti-Collagen

(17) Plet1 is an epigenetically regulated cell surface protein that provides essential cues to direct trophoblast stem cell differentiationScientific reportsApril 28, 2016Murray A, Sienerth AR, Hemberger M.gift from C. Blackburn), mouse anti-Esrrb 1:400 (R&D Systems MAB1499), anti-Tfap2c 1:400 (R&D Systems AF5059), mouse anti-Cdh3 1:100 (NeoMarkers MS-1741-S0), and mouse anti-Cdh1 1:100 (BD Biosciences 610181).

(18) Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networksGenes & developmentDecember 1, 2015Latos PA, Sienerth AR, Murray A, Senner CE, Muto M, Ikawa M, Oxley D, Burge S, Cox BJ, Hemberger M.(Santa Cruz Biotechnology, sc-9645), anti-Eomes (Abcam, ab23345; R&D Systems, MAB 6166), anti-Tfap2c (R&D System, AF5059), anti-tubulin (Abcam ab6160), and ImmunoCruz IP/WB Optima System C (sc-45040), E (sc-45042), or A (sc-45038). ChIP-seq Immunoprecipitations

(19) Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infectionCell reports. MedicineJanuary 1, 0001"Ruan D, Ye ZW, Yuan S, Li Z, Zhang W, Ong CP, Tang K, Ka Ki Tam TT, Guo J, Xuan Y, et al."RRID:AB_10853505 Anti-KRT7,Santa Cruz Biotechnology,Cat# sc-70936; RRID:AB_2234501 Anti-AP-2 gamma,R and D Systems,Cat#AF5059; RRID:AB_2255891 Anti-HLA-G,Abcam,Cat#ab7759; RRID:AB_306053 Anti-CD46,BioLegend,Cat#352403; RRID:AB_10897448 Anti-ZO-1,ABclonal,Cat#A0659;

(20) Trophoblast organoids as a model for maternal-fetal interactions during human placentationNatureJanuary 1, 0001"Turco MY, Gardner L, Kay RG, Hamilton RS, Prater M, Hollinshead MS, McWhinnie A, Esposito L, Fernando R, Skelton H, et al."

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AP-2 gamma Antibody

AP-2 gamma Antibody

AP-2 gamma Antibody

AP-2 gamma Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (20)

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AP-2 gamma Antibody from R&D Systems, a Bio-Techne Brand

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