Anti-PBP2a Antibody from RayBiotech

Yes, the Anti-PBP2a Antibody has been shown to be effective in detecting methicillin resistance in Staphylococcus species, particularly through immunofluorescence techniques. In a study, it was utilized to identify PBP2a protein expression in clinical isolates of Staphylococcus pseudintermedius, demonstrating its applicability in diagnosing methicillin resistance.

In the study referenced, the immunofluorescence method using the Anti-PBP2a Antibody exhibited 100% specificity and 64.3% sensitivity when compared to PCR as the gold standard for detecting the mecA gene, indicating that while it is highly specific, there may be variability in sensitivity depending on the isolate.

Yes, the Anti-PBP2a Antibody can be applied to identify methicillin resistance independently of the staphylococcal species, making it suitable for use in both human and animal samples, as indicated by its performance in the study involving canine and human isolates.

The Anti-PBP2a Antibody has been validated for use in Western Blotting and ELISA, and it has also been successfully applied in immunofluorescence assays, allowing for versatile applications in research and diagnostics related to methicillin resistance.