MCM5 Antibody

Product Specs
ItemMCM5 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $459.00Supplier Page View Company Product Page
Catalog NumberNB100-79778
Concentration1.0 mg/ml
Quantity100 ul
FormatTris-Citrate/Phosphate (pH 7.0 - 8.0)
HostRabbit
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
TargetMCM5
ImmunogenThe immunogen recognized by this antibody maps to a region between residues 1 and 50 of human Minichromosome Maintenance 5 using the numbering given in entry NP_006730.2 (GeneID 4174)
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaCancer, Cell Cycle and Replication, Core ESC Like Genes, DNA Repair, Stem Cell Markers
IsotypeIgG
NCBI Full Gene Nameminichromosome maintenance complex component 5
NCBI Gene AliasesP1-CDC46, CDC46, MGORS8
Antibody TypePrimary Antibodies
StorageStore at 4C. Do not freeze

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 100 ul

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

(1) Lactate in breast cancer cells is associated with evasion of hypoxia-induced cell cycle arrest and adverse patient outcomeHuman CellMarch 13, 2024Yamin Liu, Yasir Suhail, Ashkan Novin, Junaid Afzal, Aditya Pant, Kshitizprimary antibodies were used for labeling. With HIF-1α (Cat.# ab179483; 1:200; abcam), MCM 5 (cat# NB100–79778, Novus) following Alexa Fluor Secondary Antibodies (ThermoFisher) was used: Alexa Fluor 488 (A32731).

(2) MCM proteins are negative regulators of hypoxia-inducible factor 1Molecular cellJanuary 1, 0001"Hubbi ME, Luo W, Baek JH, Semenza GL."

(3) A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replicationScience signalingJanuary 1, 0001"Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL."

(7) Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progressionProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL."

MCM5 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand