LKB1 (D60C5) Rabbit mAb 3047S from Cell Signaling Technology

Product Specs
ItemLKB1 (D60C5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3047S
Quantity100 µl
ApplicationsW, W-S
ReactivityH, M, R, Mk
TargetLKB1
HostRabbit
NCBI Gene AliasesLKB1, PJS, hLKB1
ClonalityMonoclonal
NCBI Full Gene Nameserine/threonine kinase 11
Research AreaMetabolism
IsotypeIgG
CloneD60C5
Molecular Weight54

Questions and Answers

Can this antibody be used to study LKB1 in the context of cancer research?

Yes, the LKB1 (D60C5) Rabbit monoclonal antibody has been utilized in various cancer studies. For instance, it was referenced in research examining the role of LKB1 in KRAS-LKB1 mutant lung cancer, highlighting its importance in tumor microenvironment interactions and immune cell recruitment ().

Is this antibody effective for Western blot applications?

The LKB1 (D60C5) Rabbit monoclonal antibody has been shown to work effectively in Western blot applications, as evidenced by its use in multiple studies to detect LKB1 protein levels in various experimental setups, including those involving tumor models and metabolic studies (, ).

What species can this antibody detect?

This antibody is reactive with several species, including humans, mice, rats, and non-human primates, making it versatile for comparative studies across different model organisms ().

Are there any specific pathways or processes where this antibody has been highlighted in the literature?

Yes, the LKB1 antibody has been implicated in studies focusing on the LKB1-AMPK signaling pathway, which is crucial for regulating cellular energy homeostasis and metabolism. For example, it has been used to investigate the role of LKB1 in mitochondrial metabolism and myelination processes in Schwann cells ().

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Targeting CRTC2 reverses STK11 mutant NSCLC tumor resistance to immunotherapyProc Natl Acad Sci U S AApril 28, 2026Dimitri Robay, Ole Ackermann, Laurent Laborde, Xingyi Shi, Federico Oreglia, Ramona Stump, Sabina Ciaghi, Giorgio G. Galli, Laura Holzer, Lorraine Villemin, et al.transferred onto PVDF membranes (Thermo Scientific) and probed with the following antibodies: LKB1 (CST, #3047), CRTC1 (CST, #2587), CRTC2 (Millipore, # MABN695 for mouse samples and Abcam, # ab109081 for human

(2) Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in AsthmaImmun Inflamm DisApril 5, 2026Guangxing Li, Liangchang Li, Zhiguang Wang, Yihua Piao, Yilan Song, Li Li, Chang Xu, Xiaowan Li, Guanghai Yan(ab38898; Abcam), LC3‐I/II (ABC929; Sigma), Beclin‐1 (ab62557; Abcam), LKB1 (Ser428; #3482; CST), LKB1 (#3047; CST), AMPKα (Thr172; #2535; CST), AMPKα (#5831; CST), mTOR (Ser2448; #2971; CST), mTOR (#2983; CST),

(3) Monocyte Preprogramming by Tobacco Carcinogens and Fructose Intake Accelerates Lung Cancer Progression via Metabolic and Epigenetic PathwaysInt J Biol SciMarch 25, 2026Jee Hwan Ahn, Hye-Young Min, Jisung Kim, Xuan Wei, Namwon Kim, Ho-Young Leeno. 2523), STAT3 (cat. no. 9139), arginase 1 (ARG1, cat. no. 93668), liver kinase B1 (LKB1, cat. no. 3047), and TGF-β (cat. no. 3711) were purchased from Cell Signaling Technology (Danvers, MA, USA). Anti-β-actin

(4) Cirsiliol alleviates diabetic cardiomyopathy by inhibiting oxidative stress and improving energy metabolism through the PPAR-α/AMPK pathwayScientific ReportsDecember 11, 2025Jing Tao, Siqi Liu, Yunzhi Ling, Hanlin Bai, Lei Liu, Ru Yu, Guangling Li(Catalog # 12153), MCP-1 (Catalog # 2029), PPAR-α (Catalog # 2435), AMPK (Catalog # 5831), LKB1 (Catalog # 3047), and ACADM (Catalog # 4321) were purchased from Cell Signaling Technology. The antibody for IL-8 (Catalog

(5) Targeting mitochondrial phosphatidylethanolamine alters mitochondrial metabolism and proliferation in hepatocellular carcinomaOncogenesisDecember 8, 2025Melina C. Mancini, Cameron P. McCall, Robert C. Noland, Wagner S. Dantas, Timothy D. Heden9482, Cell Signaling Technology), Parkin (4211, Cell Signaling Technology), liver kinase B1 (LKB1, 3047, Cell Signaling Technology), phosphorylated LKB1S428 (3482, Cell Signaling Technology), adenosine monophosphate

(6) Enduring Effects of Humanin on Mitochondrial Systems in TBI PathologyBiomoleculesDecember 6, 2025Pavan Thapak, Zhe Ying, Fernando Gomez-Pinilla(Cell Signaling Technology, Danvers, MA, USA, Cat#2532S), LKB1 (Cell Signaling Technology, Danvers, MA, USA, Cat#3047S), PSD95 (Cell Signaling Technology, Danvers, MA, USA), p-STAT3 (Tyr705) (Cell Signaling Technology,

(7) Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD+ biosynthesis and thermogenesis in micenpj AgingNovember 24, 2025Kiyoshi Yoshioka, Takumi Sugimoto, Mamoru Oyabu, Naoki Ito, Aoi Kodama, Yasutomi Kamei, Shin-ichiro Imaifollowing primary antibodies were used: NAMPT (A300-372A, Bethyl), Phospho(Ser428)-LKB1 (#3482), LKB1 (#3047), Phospho(Thr172)-AMPKα (#2535), AMPKα (#2532, Cell Signaling Technology), Transferrin (A80-128P, Bethyl),

(8) Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulationJournal of Experimental MedicineNovember 3, 2025Jinjin Xu, Lingjia Kong, Elizabeth A. Creasey, Sneha Rath, Lei Deng, Julian Avila-Pacheco, Chenhao Li, Blayne A. Oliver, Tyler T. Dao, Angela R. Shih, et al.(Cell Signaling Technology, catalog 3482S, RRID: AB_2198321), LKB1 (D60C5) (Cell Signaling Technology, catalog 3047, RRID: AB_2198327), MTHFD2 polyclonal antibody (Protein Tech, catalog 12270–1-AP, RRID: AB_2147525),

(9) The antiadipogenic effect of the pentacyclic triterpenoid isoarborinol is mediated by LKB1-AMPK activationPLOS OneSeptember 3, 2025Yesenia Arcos-Reyes, Gildardo Rivera, Laurence A. Marchat, Juan Salas-Benito, Gilberto Mandujano-Lázaro, Moisés Monzón-Gualito, Esther Ramírez-MorenomAb #5831 (1:5000); Phospho-LKB1 (Ser428) (C67A3) Rabbit mAb #3482 (1:5000); LKB1 (C60C5) Rabbit mAb #3047 (1:5000); β-Actin (13E5) Rabbit mAb #4970 (1:1000). Finally, the membrane was probed with horseradish

(10) Sodium butyrate attenuates lipid metabolism disorder via improving mitochondrial function and activating autophagy in LMH cellsPoultry ScienceJune 25, 2025Sasa Miao, Mengru Xu, Fang Liu, Xinyang Dong, Xiaoting Zou, Tao Zeng, Lizhi Lu"Cell signaling technology (Boston, MA, USA)",3054S,Rabbit LKB1,"Cell signaling technology (Boston, MA, USA)",3047T,Rabbit p-AMPK,"Abcam (Cambridge, MA, USA)",ERP5683,Rabbit AMPK,"Abcam (Cambridge, MA, USA)",Y365,Rabbit p-mTOR,"Abcam

(11) Inhibition of serotonin-Htr2b signaling in skeletal muscle mitigates obesity-induced insulin resistanceExperimental & Molecular MedicineJune 2, 2025Suhyeon Park, Hyeongseok Kim, Soyeon Shin, Yeongmin Kim, Yunwon Kang, Hye-Na Cha, So-Young Park, Sangkyu Park, Chang-Myung OhPhospho-LKB1 (Ser428) (Cell Signaling Technology, #3482), rabbit LKB1 (Cell Signaling Technology, #3047), rabbit SIRT1 (Abcam, ab189494), rabbit TPH1 (Invitrogen, MA5-32209), rabbit Phospho-PI3 Kinase p85

(12) Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocationNat Prod BioprospectApril 7, 2025Yu Shi, Xing-de Wu, Yanli Liu, Yu Shen, Hui Qu, Qin-Shi Zhao, Ying Leng, Suling Huangantibodies against phospho-Akt (Ser473) (# 9271), phospho-Akt (Thr308) (#9275), pan-Akt (#9272), LKB1 (#3047), GLUT4 (#2213), phospho-AS160 (Thr642) (#8881), phospho-HDAC4/5/7 (Ser426/Ser259/Ser155) (#3443), GAPDH

(13) A highland-adaptation variant near MCUR1 reduces its transcription and attenuates erythrogenesis in TibetansCell GenomMarch 12, 2025Ping J, Liu X, Lu Y, Quan C, Fan P, Lu H, Li Q, Wang C, Zhang Z, Liu M, et al.Proteintech, China), phosphorylated Raptor (p-Raptor, Ser792; #89146; Cell Signaling Technology, USA), LKB1 (#3047; Cell Signaling Technology, USA), phosphorylated LKB1 (p-LKB1, Ser428; #3482; Cell Signaling Technology,

(14) A novel ER stress regulator ARL6IP5 induces reticulophagy to ameliorate the prion burdenAutophagyMarch 1, 2025Kamble K, Kumar U, Aahra H, Yadav M, Bhola S, Gupta S.(Cell Signaling Technology, 4263; 1:1000 WB), rabbit monoclonal anti-STK11 (Cell Signaling Technology, 3047; 1:1000 WB), HRP-conjugated goat polyclonal anti-rabbit (Cell Signaling Technology, 7074; 1:10000 WB),

(15) Partial activation of salt-inducible kinase 3 delays the onset of wakefulness and alleviates hypersomnia due to the lack of protein kinase A-phosphorylation siteSLEEPFebruary 10, 2025Shinya Nakata, Tomoyuki Fujiyama, Fuyuki Asano, Haruna Komiya, Noriko Hotta-Hirashima, Motoki Juichi, Daiki Komine, Miyo Kakizaki, Aya Ikkyu, Seiya Mizuno, et al.Cell Signaling Technology #8312), anti-LKB1 (D60C5) antibody (rabbit, monoclonal, Cell Signaling Technology #3047), anti-GAPDH (D16H11) XP antibody (rabbit, monoclonal, Cell Signaling Technology #5174). After incubation

(16) KEAP1 mutations as key crucial prognostic biomarkers for resistance to KRAS-G12C inhibitorsJ Transl MedJanuary 17, 2025Linyan Tian, Chengming Liu, Sufei Zheng, Huiyang Shi, Fang Wei, Wenxin Jiang, Yucheng Dong, Haiyan Xu, Enzhi Yin, Nan Sun, et al.antibodies specific for KEAP1 (Cell Signalling Technology, #8047), STK11/LKB1 (Cell Signalling Technology, #3047), PD-L1 (Cell Signalling Technology, #13684T), or GAPDH (Abcam, Cambridge, UK, #ab8245). After primary

(17) Mechanisms of Response and Tolerance to Active RAS Inhibition in KRAS -Mutant Non–Small Cell Lung CancerCancer DiscoveryNovember 1, 2024Haniel A. Araujo, Ximo Pechuan-Jorge, Teng Zhou, Minh Truong Do, Xin Hu, Frank R. Rojas Rojas Alvarez, Maria E. Salvatierra, Heladio P. Ibarguen, Richard Lee, Rashi Raghulan, et al.ChemiDoc Bio-Rad Imager and analyzed with Image Lab software. Primary antibodies used were LKB1 (CST, #3047), p53 (CST, #2524), vinculin (Sigma, #V9131), KEAP1 (CST, #7705), NRF2 (Proteintech, #163 9 6–1-AP),

(18) Impact of protein and small molecule interactions on kinase conformationseLifeAugust 1, 2024Valentina Kugler, Selina Schwaighofer, Andreas Feichtner, Florian Enzler, Jakob Fleischmann, Sophie Strich, Sarah Schwarz, Rebecca Wilson, Philipp Tschaikner, Jakob Troppmair, et al.rabbit-anti-Phospho-AMPKα (Thr172) (40H9) (Cell Signaling, 2535), rabbit-anti-LKB1 (D60C5) (Cell Signaling, 3047), rabbit-anti-Vinculin (Cell Signaling, 4650), rabbit-anti-RIP (D94C12) XP (Cell Signaling, 3493), rabbit-anti

(19) Iron Regulates Cellular Proliferation by Enhancing the Expression of Glucose Transporter GLUT3 in the LiverCellsJuly 4, 2024Ribeiro KS, Karmakar E, Park C, Garg R, Kung GP, Kadakia I, Gopianand JS, Arun T, Kisselev O, Gnana-Prakasam JP.cocktail. Subsequently, cell lysates were incubated with the primary antibody LKB1 (Cell Signaling, Cat #3047S) overnight at 4 °C followed by incubation with Protein A/G magnetic beads. The immunocomplexes were

(20) TBC1D23 mediates Golgi-specific LKB1 signalingNature CommunicationsFebruary 27, 2024Yingfeng Tu, Qin Yang, Min Tang, Li Gao, Yuanhao Wang, Jiuqiang Wang, Zhe Liu, Xiaoyu Li, Lejiao Mao, Rui zhen Jia, et al.anti-TBC1D23 (Proteintech, 17002-1-AP, Western blot (WB) 1:1000), rabbit anti-LKB1(Cell Signaling Technology, 3047, WB 1:1000), rabbit anti-FAM21 (donated by Dr. Daniel D. Billadeauh, WB 1:1000), rabbit anti-AMPKα (Cell Signaling Technology

Write a Review

(1)

12/3/2015Human LKB1 Antibody A MOur lab works with a number of kinases, including LKB1/STK11. We recently transfected LKB1 deficient cells with an expression vector for human LKB1, and I was able to prove the plasmid-driven LKB1... Read Review

LKB1 (D60C5) Rabbit mAb

LKB1 (D60C5) Rabbit mAb from Cell Signaling Technology

Description

Questions and Answers

Cell Signaling Technology

Citations (135)

Reviews

LKB1 (D60C5) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map