HDAC1 (10E2) Antibody sc-81598 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHDAC1 (10E2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-81598
Antibody TypePrimary Antibodies
NCBI Gene AliasesMommeD5, HD1, RPD3L1, KDAC1, GON-10, RPD3, Hdac1-ps
ApplicationsWB, IP, IF, IHC(P), ELISA
Reactivitymouse, rat, human
FormatPurified
Conjugate/TagUnconjugated
Hostmouse
ClonalityMonoclonal
NCBI Full Gene Namehistone deacetylase 1
TargetHDAC1
IsotypeIgG1
Clone10E2
Quantity200 µg/ml

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) E3 ligase UHRF2 hijacks nuclear TBK1 to epigenetically repress type I interferons expressionInt J Biol SciMay 18, 2026Wenwen Huang, Renjie Song, Qicong Shen, Yang Shi, Xi Wang, Nan Li, Qian Zhang, Xuetao CaoCell Signaling Technology, 4302), antip-IRF3 (1:1000; Cell Signaling Technology, 4947), anti-UHRF2 (1:200; Santa Cruz, sc-81598), anti-HDAC1 (1:200, Santa Cruz, sc-81598), anti-LaminA/C (1:2000; Cell Signaling Technology, 2032),

(2) Fibroblast histone deacetylase-1 promotes kidney interstitial fibrosis following ischemia-reperfusion injuryAmerican Journal of Physiology-Renal PhysiologyApril 1, 2026Huy Nguyen, Luciano D. Mendoza, Ariana S. Oliver, Kaitlyn J. Aldaz, Anna D. Montgomery, Malgorzata Kasztan, Subhashini Bolisetty, Kelly A. Hyndmanmono,Bio-Rad,MCA497GA,150384,0.1,,100, Fibronectin,Rb poly,Sigma Aldrich,F3648,047M4809V,n.r.,5000,, HDAC1,Ms mono,Santa Cruz Biotechnology,sc-81598,D0224,200 μg/mL,,100,1000 HDAC1-488,Rb mono,Abcam,ab192469,GR198516-2,0.5,,100, OctA-probe (H-5),Ms

(3) Intergenerational Effects of Neonicotinoid Thiacloprid in Murine Prostate Tissue Are Associated with Epigenetic Alterations in Homeobox Hox GenesInternational Journal of Molecular SciencesMarch 24, 2026Ouzna Dali, Shereen Cynthia D’Cruz, Chaima Diba Lahmidi, Tayeb Mohammed Belkhir, Theo De Gestas, Christine Kervarrec, Pierre-Yves Kernanec, Fatima Smagulovamouse BRD4 (1:500, sc-518021, Santa Cruz, City of Santa Cruz, CA, USA) or anti-mouse HDAC1 (1:500, sc-81598, Santa Cruz, City of Santa Cruz, CA, USA) and anti-rabbit KDM5A (1:500, ab194286, Abcam, Cambridge,

(4) Magnetoelectric nanoparticles drive TAF9B+ TH2 cell expansion to alleviate inflammationSci AdvFebruary 13, 2026Jia Song, Lulu Liu, Ziqi Liu, Shuo Liu, Zhang Zhang, Xinyu Liu, Boon Chin Heng, Yaojin Wang, Dan Lu, Xuehui Zhang, et al.Abcam, ab133357), anti–β-catenin (1:5000; Abcam, ab32572), anti-HDAC1 (1:1000; Santa Cruz Biotechnology, sc-81598), anti-puromycin (1:1000; Merck Millipore, MABE341), anti-TAF9B (1:1000; Signalway Antibody, 45238),

(5) Imaging brain class I histone deacetylase changes in the Lewy body dementias and Parkinson’s diseaseClinical EpigeneticsJanuary 24, 2026Anna E. Goodheart, Chi-Hyeon Yoo, Aline Fassini, Tewodros M. Dagnew, Rong Ye, Robin Striar, Moqing Quan, Anna K. Rattray, Tyler N. Meyer, Erin Peterec, et al.Sections were then incubated overnight at 4 °C with primary antibodies against HDAC1 (1:100; Santa Cruz, SC-81598), HDAC2 (1:200; Abcam, AB124974), and HDAC3 (1:100; Abcam, AB32369). Following several washes in phosphate-buffered

(6) Spatiotemporal regulation of MKK4 dictates switch-like JNK activation and binary cell-fate decisionsNature CommunicationsJanuary 8, 2026Hisashi Moriizumi, Takanori Nakamura, Yuji Kubota, Ryosuke Hiranuma, Youngmin Cho, Toru Kawanishi, Hiroyuki Takeda, Takashi Suzuki, Mutsuhiro Takekawa(sc-7392), anti-GST B-14 (sc-138), anti-ERK1/2 C-9 (sc-514302), anti-MEK1 H-8 (sc-6250) and anti-HDAC1 10E2 (sc-81598) (Santa Cruz Biotechnology); anti-β-actin 6D1 (Wako, 010-27841); rabbit monoclonal anti-phospho-JNK

(7) Sphingomyelin regulates astrocyte activity by regulating NF-κB signaling via HDAC1/3 expressionJournal of Lipid ResearchNovember 4, 2025Ryo Kadowaki, Hana Hirose, Gai Takimoto, Takafumi Kohama, Hiroyuki Nakamuraphospho-Ser536-p65 (Cat# sc-136548), TNF receptor 1 (TNFR1; Cat#sc-9436), histone deacetylase 1 (HDAC1; Cat# sc-81598), HDAC3 (Cat# sc-376957), calnexin (Cat# sc-46669), lamin B1 (Cat# sc-374015), and flotillin-1 (Cat#

(8) Age-Dependent Histone Deacetylase 3 Regulation by βA3/A1-Crystallin and Inositol Hexaphosphate in Retinal Pigmented Epithelial Cells Reveals a Novel Pathway in Age-Related Macular DegenerationAging cellSeptember 1, 2025Chatterjee S, Ghosh S, Sin Z, Babu VS, Preval LV, Davis E, Tran N, Bammidi S, Gautam P, Hose S, et al.anti‐HDAC3 (Santa Cruz Biotechnology, Cat #: sc‐376957), anti‐HDAC1 (Santa Cruz Biotechnology, Cat #: sc‐81598), anti‐HDAC2 (Santa Cruz Biotechnology, Cat #: SC‐7899), anti‐HDAC8 (Biolegend, Cat #: 685504), anti‐pHDAC3

(9) Evaluating endometrial response to human chorionic gonadotropin: alterations in epigenetic regulation and extracellular vesicle cargo of endometrial stromal cellsHuman Reproduction OpenAugust 14, 2025Deimantė Žukauskaitė, Erika Girniūtė, Rūta NavakauskienėMA, USA) Cat No. 9649, RRID: AB_823528), HDAC1 (Santa Cruz Biotechnology (Dallas, TX, USA) Cat No. sc-81598, RRID: AB_2118083), and HDAC2 (Santa Cruz Biotechnology Cat No. sc-9959, RRID: AB_627704), H3K27ac (Cell Signaling Technology

(10) Imaging brain class I histone deacetylase changes in the Lewy body dementias and Parkinson's diseaseResearchSquareAugust 11, 2025Anna Goodheart, Chi-Hyeon Yoo, Aline Fassini, Tewodros Dagnew, Rong Ye, Robin Striar, Moqing Quan, Anna Rattray, Tyler Meyer, Erin Peterec, et al.Sections were then incubated overnight at 4°C with primary antibodies against HDAC1 (1:100; Santa Cruz, SC-81598), HDAC2 (1:200; Abcam, AB124974), and HDAC3 (1:100; Abcam, AB32369). Following several washes in phosphate-buffered

(11) Loss of Elmsan1 in cardiomyocytes leads to age-dependent cardiac dysfunction and reduced lifespanAmerican Journal of Physiology-Heart and Circulatory PhysiologyAugust 1, 2025Meimei Wang, Hui Li, Chaoshan Han, Yunxi Chen, Lihao He, Min Xie, Hind Lal, Vladimir G. Fast, Douglas R. Moellering, Jianyi Zhang, et al.anti-ANP (1:2000, PA5–29559, Thermo Fisher), OXPHOS (1:1000, #ab110411, Abcam), anti-Hdac1 (1:200, sc-81598, Santa Cruz), anti-Hdac2 (1:10000, 12922–3-AP, Proteintech), and anti-Dnttip1 (1:100, sc-166296, Santa Cruz

(12) Liver oval cells in response to HDAC1 inhibitor trichostatin A: immunohistochemical characterization using OV-6 hepatic expressionAnatomy & Cell BiologyJune 30, 2025Hussein Abdellatif, Ruqaiya Al Al Jabri, Halima Albalushi, Mohamed Al Al Mushaiqriexpression of HDAC1 in hepatocytes and reactive ducts was determined utilizing anti-HDAC1 antibody (sc-9959, sc-81598; Santa Cruz Biotechnology). In three xylene cycles of five minutes each, tissue sections (5 μm thickness)

(13) The metastatic role of the CXCL10-CXCR3 axis and its therapeutic potential in osteosarcomaJournal of Bone OncologyJune 1, 2025Benjamin B. Gyau, Junyan Wang, Xiang Chen, Margaret A. Clement, Zoe D. Man, Angela M. Major, Mathew C. Weiser, Jun Xu, John Hicks, Tsz-Kwong Man(1:1000, 3656, Cell Signaling), GAPDH (1:10000, sc-32233, Santa Cruz, Dallas, Texas, USA), HDAC1 (1:1000, sc-81598, Santa Cruz), and CXCL10 (1:1000, 14969, Cell Signaling). Secondary antibodies used were anti-rabbit

(14) 3'UTR RNA editing driven by ADAR1 modulates MDM2 expression in breast cancer cellsFunct Integr GenomicsMay 17, 2025Elanur Almeric, Deniz Karagozoglu, Mustafa Cicek, Didem Naz Dioken, Huseyin Avni Tac, Esra Cicek, Busra Aytul Kirim, Irmak Gurcuoglu, Osman Ugur Sezerman, Nurhan Ozlu, et al.(Abcam, ab168809), anti-CSTF2 (Abcam, ab72297), and anti-Biotin (Abcam, ab53494), anti-HDAC (Santa Cruz, sc-81598) and anti-TUBA1A (Cell Signaling, 2144) primary and appropriate secondary antibodies. Mass spectrometry analysis

(15) CXXC5 is a ubiquitinated protein and is degraded by the ubiquitin-proteasome pathwayProtein SciMay 15, 2025Hazal Ayten, Pelin Toker, Gizem Turan Duman, Çağla Ece Olgun, Öykü Deniz Demiralay, Büşra Bınarcı, Gizem Güpür, Pelin Yaşar, Hesna Begüm Akman, Per Haberkant, et al.Antibodies for ERα (Cat # sc‐543), Cyclin B1 (Cat # sc‐245), Cyclin E (Cat # sc‐247), and HDAC1 (Cat # sc‐81598) were obtained from Santa Cruz Biotechnology (SCBT, Santa Cruz, CA, USA). The antibody for the Flag

(16) DUBR non-coding RNA regulates gene expression by affecting AP-1 enhancer accessibilityFunct Integr GenomicsMarch 21, 2025Simone D. Hall, Khoa Tran, Jonathan Zhu, Tong Su, Colleen A. McHugh(10284-1-AP, Proteintech), DNMT1 (NB100-56519, Novus Biologicals, USA), CHD4 (A11574, Abcam), HDAC1 (sc-81598, Santa Cruz Biotechnology), HDAC2 (A2084, Abcam). The beads/antibody mixtures were incubated for 60

(17) MS275 induces tumor immunosuppression by upregulating PD-L1 and enhances the efficacy of anti-PD-1 immunotherapy in colorectal cancerCancer Immunol ImmunotherMarch 17, 2025Deng Tang, Zhigang Mao, Sihan Chen, Mi Su, Siqi Lan, Ruiting Yan, Qi Xiang, Xianxian Zhao, Ji Zhang, Yufang Wangantibody(#7074), all of these were purchased from Cell Signaling Technology (Danvers, MA, USA). Anti-HDAC1(sc-81598) and anti-HDAC3(sc-17795) were purchased from Santa Cruz, Anti-HDAC2(abs136328) and goat anti-mouse

(18) A reappraisal of cell cycle phase enrichment in synchronized estrogen receptor-positive cell models derived from breast adenocarcinomasSci RepFebruary 18, 2025Pelin Toker, Hazal Ayten, Öykü Deniz Demiralay, Büşra Bınarcı, Gizem Turan, Çağla Ece Olgun, Pelin Yaşar, Hesna Begüm Akman, Mesut MuyanBioTechne-Tocris (Bristol, UK). Antibodies for ERα (Cat # sc-543), Cyclin E (Cat # sc-247), and HDAC1 (Cat # sc-81598) were obtained from Santa Cruz Biotechnology (SCBT, Santa Cruz, CA, USA), and the antibody for Cyclin

(19) Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complexCell communication and signaling : CCSJanuary 22, 2025Wang YW, Luo CW.(GeneTex, GTX108971), SMAD2 (Cell signaling, 5339), SMAD3 (Cell signaling, 9523), HDAC1 (Santa Cruz, sc-81598), ATF3 (Santa Cruz, sc-518032), TGIF1 (Santa Cruz, sc-17800), Ac-H3 (Santa Cruz, sc-36616), and β-actin

(20) Transcriptional corepressor activity of CtBP1 is regulated by ISG15 modificationAnimal Cells and SystemsDecember 31, 2024Yun Hwan Lim, Yoon Jin Park, Jieun Lee, Jung Hwa Kimsc-40), HA (Cell signaling, #3724), Flag (Sigma, F3165), GFP (Proteintech, 66002), HDAC1 (Santa Cruz, sc-81598), HDAC4 (Proteintech 17449-1-AP), β-actin (Sigma–Aldrich, A1978). Western blotting PBS-washed cells

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HDAC1 (10E2) Antibody

HDAC1 (10E2) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HDAC1 (10E2) Antibody from Santa Cruz Biotechnology, Inc.

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