CLIC1 (356.1) Antibody sc-81873 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCLIC1 (356.1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $333.00Supplier Page View Company Product Page
Catalog Numbersc-81873
Antibody TypePrimary Antibodies
NCBI Gene AliasesClcp, G6, CL1C1, NCC27, CLCNL1
Clone356.1
Quantity100 µg/ml
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, IHC(P), ELISA
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
NCBI Full Gene Namechloride intracellular channel 1
TargetCLIC1
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progressionJournal of Translational MedicineNovember 22, 2025Jian Yang, Zhu Yu, Yue Feng, Shengyu Wang, Changhua Li, Yuantian Mao, Wenqian Xu, Junqiang Chenintensities were quantified using ImageJ. Primary antibodies used in this study included anti-CLIC1 (#sc-81873; Santa Cruz Biotechnology, USA), anti-PKM2 (#15822-1-AP; Proteintech, China), anti-PKM1 (#15821-1-AP;

(2) Targeting Clic1 for the treatment of obesity: A novel therapeutic strategy to reduce food intake and body weightMolecular metabolismOctober 1, 2023Zapata RC, Zhang D, Yoon D, Nasamran CA, Chilin-Fuentes DR, Libster A, Chaudry BS, Lopez-Valencia M, Ponnalagu D, Singh H, et al.where quantified using densitometer in ImageLab. The following antibodies were used: anti-Clic1 (1:100, sc-81873, Santa Cruz Biotechnology), anti-beta actin (1:2000, 3700, Cell Signaling), anti-Na+, K+-ATPase (1:1000,

(3) Chloride Intracellular Channel Protein 1 Expression and Angiogenic Profile of Liver Metastasis of Digestive OriginCurrent issues in molecular biologyFebruary 6, 2023Ceausu AR, Ciolofan A, Blidisel A, Cosma AA, Gaje PN, Cretu O.CLIC1 (356.1, dilution 1:2000, incubation time—1 h at room temperature; from Santa Cruz Biotechnology, SC 81873, Santa Cruz, CA, USA); CD34 (clone QBEnd10, RTU, incubation time—20 min—Leica Biosystem Newcastle Ltd.,

(4) The Mutually Mediated Chloride Intracellular Channel Protein 1 (CLIC1) Relationship between Malignant Cells and Tumor Blood Vessel Endothelium Exhibits a Significant Impact on Tumor Angiogenesis, Progression, and Metastasis in Clear Cell Renal Cell Carcinoma (ccRCC)CancersDecember 3, 2022Ferician AM, Ferician OC, Nesiu A, Cosma AA, Caplar BD, Melnic E, Cimpean AM.immunostaining protocol. Monoclonal mouse-anti-human CLIC1 antibodies IgG2a (100 g/mL, clone 356.1, code sc-81873, Santa Cruz Biotechnology, dilution 1:200) were incubated for 30 min at room temperature, using a biotin-free

(5) A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channelsJournal of cell scienceAugust 1, 2022Varela L, Hendry AC, Cassar J, Martin-Escolano R, Cantoni D, Ossa F, Edwards JC, Abdul-Salam V, Ortega-Roldan JL.

(6) Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivativesJournal of experimental & clinical cancer research : CRFebruary 8, 2022Barbieri F, Bosio AG, Pattarozzi A, Tonelli M, Bajetto A, Verduci I, Cianci F, Cannavale G, Palloni LMG, Francesconi V, et al.

(7) CLIC1 Expression in Skin Biopsies from Patients With Rheumatoid and Psoriatic Arthritis as a Potential Tool to Predict Therapy ResponseIn vivo (Athens, Greece)September 1, 2021Bordean L, Chis M, Raica M, Cotoi OS, Ceausu AR, Avram C, Cimpean AM.

(8) Liver Metastatic Colorectal Tumor Cells Change Their Phenotype During Consecutive Passages on Chick Embryo Chorioallantoic Membrane: Lessons from the Lab to the ClinicIn vivo (Athens, Greece)September 1, 2021Ceaușu RA, Ciolofan A, Blidișel A, Crețu OM, Cimpean AM, Raica M.

(9) Study on Cancer Cell Invasiveness via Application of Mechanical Force to Induce Chloride Ion EffluxAnalytical chemistryJuly 6, 2021Yamagishi A, Ito F, Nakamura C.

(10) CLIC4 and CLIC1 bridge plasma membrane and cortical actin network for a successful cytokinesisLife science allianceFebruary 1, 2020Uretmen Kagiali ZC, Saner N, Akdag M, Sanal E, Degirmenci BS, Mollaoglu G, Ozlu N.Sigma-Aldrich). The primary antibodies were used as 1:200 anti-CLIC4 (sc-135739; Santa Cruz), 1:200 anti-CLIC1 (sc-81873; Santa Cruz), 1:1,000 anti-α-tubulin (2144; Cell Signaling), 1:200 anti-β-tubulin (2128; Cell Signaling),

(11) MicroRNA‑124 negatively regulates chloride intracellular channel 1 to suppress the migration and invasion of liver cancer cellsOncology reportsOctober 1, 2019Yue X, Cui Y, You Q, Lu Y, Zhang J.(Amersham; GE Healthcare). Primary antibody against CLIC1 (1:1,000; Santa Cruz Biotechnology, Inc.; cat. no. sc-81873) and tubulin (1:5,000; Santa Cruz Biotechnology, Inc.; cat. no. sc-365791) was applied after blocking

(12) Intracellular Chloride Ion Channel Protein-1 Expression in Clear Cell Renal Cell CarcinomaCancer genomics & proteomicsJuly 1, 2019Nesiu A, Cimpean AM, Ceausu RA, Adile A, Ioiart I, Porta C, Mazzanti M, Camerota TC, Raica M.

(13) The Structural Function of Nestin in Cell Body Softening is Correlated with Cancer Cell MetastasisInternational journal of biological sciencesJanuary 1, 2019Yamagishi A, Susaki M, Takano Y, Mizusawa M, Mishima M, Iijima M, Kuroda S, Okada T, Nakamura C.antibody (1:500 dilution) (Rat-401; BioLegend, San Diego, CA, USA), anti-Clic1 antibody (1:500 dilution) (SC-81873; Santa Cruz Biotechnology, Dallas, TX, USA) or anti-His-tag antibody (1:1000 dilution) (D291-3; MBL,

(14) Mutual Influence of ROS, pH, and CLIC1 Membrane Protein in the Regulation of G(1)-S Phase Progression in Human Glioblastoma Stem CellsMolecular cancer therapeuticsNovember 1, 2018Peretti M, Raciti FM, Carlini V, Verduci I, Sertic S, Barozzi S, Garré M, Pattarozzi A, Daga A, Barbieri F, et al.

(15) The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motilityThe Journal of biological chemistryMarch 23, 2018Stakaitytė G, Nwogu N, Lippiat JD, Blair GE, Poterlowicz K, Boyne JR, Macdonald A, Mankouri J, Whitehouse A.Qiagen (product no. 1027416). CLIC1 and CLIC4 antibodies were purchased from Santa Cruz Biotechnology (sc-81873) and Abcam (ab76593), respectively. Antibodies were used at 1:5000 dilution. The 2T2 hybridoma was provided

(16) Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell ViabilityFrontiers in pharmacologyJanuary 1, 2018Barbieri F, Würth R, Pattarozzi A, Verduci I, Mazzola C, Cattaneo MG, Tonelli M, Solari A, Bajetto A, Daga A, et al.

(17) Tanshinone IIA Sodium sulfonate regulates antioxidant system, inflammation, and endothelial dysfunction in atherosclerosis by downregulation of CLIC1European journal of pharmacologyNovember 15, 2017Zhu J, Xu Y, Ren G, Hu X, Wang C, Yang Z, Li Z, Mao W, Lu D.

(18) The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasomeThe Journal of biological chemistryJuly 21, 2017Domingo-Fernández R, Coll RC, Kearney J, Breit S, O'Neill LAJ.

(19) CLIC1 Inhibition Attenuates Vascular Inflammation, Oxidative Stress, and Endothelial InjuryPloS oneJanuary 1, 2016Xu Y, Zhu J, Hu X, Wang C, Lu D, Gong C, Yang J, Zong L.Biotechnologies (California, USA). Anti-CLIC1 antibody was acquired from Santa Cruz Biotechnologies (sc-81873, CA, USA). Anti-Na+/K+-ATPase antibody was acquired from SanYing Biotechnology (14418-1-AP, Wuhan, China).

(20) CLIC1 a novel biomarker of intraperitoneal metastasis in serous epithelial ovarian cancerTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineJune 1, 2015Ye Y, Yin M, Huang B, Wang Y, Li X, Lou G.

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CLIC1 (356.1) Antibody

CLIC1 (356.1) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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CLIC1 (356.1) Antibody from Santa Cruz Biotechnology, Inc.

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