APH1A Antibody NB100-74360 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemAPH1A Antibody
CompanyNovus Biologicals, a Bio-Techne Brand
Price $399.00Supplier Page View Company Product Page
Catalog NumberNB100-74360
Concentration0.69 mg/ml
FormatPBS with 1 mg/ml BSA
ReactivityHuman,Mouse
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
HostRabbit
Quantity100 ug (also 0.025 mg)
TargetAPH1A
NCBI Full Gene Nameaph-1 homolog A, gamma-secretase subunit
ClonalityPolyclonal
IsotypeIgG
PurityImmunogen affinity purified
Research AreaStem Cell Markers
Antibody TypePrimary Antibodies
StorageStore at -20C. Avoid freeze-thaw cycles
NCBI Gene AliasesCGI-78, APH-1A, APH-1, 6530402N02Rik
ImmunogenSynthetic peptide, KLH conjugated, corresponding to residues C (245) R R Q E D S R V M V Y S A L R I P P E D (265) of human APH-1aL/CT

Available conjugates: Available conjugates: Unconjugated

Specificity: APH-1

Sizes Available: 100 ug (also 0.025 mg)

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

(1) ELK1 inhibition alleviates amyloid pathology and memory decline by promoting the SYVN1-mediated ubiquitination and degradation of PS1 in Alzheimer's diseaseExperimental & molecular medicineJanuary 1, 0001"Yi L, Li J, He Y, Wang J, Wang M, Guo S, Luo M, Wu B, Xu M, Tian Q, et al."anti-LC3 (1:1,000, #12741) antibodies were sourced from Cell Signaling Technology. Anti-APH1A (1:1,000, NB100-74360) antibody was purchased from Novus Biologicals. Anti-p-ELK1 Ser383 (1:500, AF3212) antibody was obtained

(2) Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondriaThe American journal of pathologyJanuary 1, 0001"Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon LA, et al."

(3) APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexesThe Journal of biological chemistryJanuary 1, 0001"Gu Y, Chen F, Sanjo N, Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT, et al."

APH1A Antibody