eEF1A Antibody 2551S from Cell Signaling Technology

Product Specs
ItemeEF1A Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number2551S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH, M, R, Mk
TargetEEF1A
HostRabbit
NCBI Gene AliasesCCS-3, CCS3, EE1A1, EEF-1, EEF1A, EF-Tu, EF1A, EF1A1, EF1alpha1, GRAF-1EF, LENG7, PTI1, eEF1A-1
NCBI Full Gene Nameeukaryotic translation elongation factor 1 alpha 1
ClonalityPolyclonal
Research AreaTranslational Control
Molecular Weight50

Questions and Answers

Can this antibody be used to study the role of eEF1A in cancer research?

Yes, the eEF1A Antibody has been utilized in studies investigating its role in cancer. For instance, in gastric cancer research, eEF1A was shown to be involved in a positive feedback circuit that promotes cell growth and metastasis, highlighting its significance in oncogenic processes ().

What applications is this antibody suitable for in my experiments?

The eEF1A Antibody is suitable for Western blotting, immunocytochemistry, and immunofluorescence. It has been effectively used in various studies to detect eEF1A protein levels and localization in different cell types (, ).

Is this antibody effective for use in mouse models?

Yes, the eEF1A Antibody has been shown to work effectively in mouse models, as it detects endogenous levels of eEF1A protein in mouse tissues. This has been demonstrated in studies involving mouse embryonic development and cancer models (, ).

What species can this antibody react with?

The eEF1A Antibody is reactive with several species, including humans, mice, rats, and non-human primates. This broad reactivity makes it a versatile tool for comparative studies across different biological systems.

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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNAInternational Journal of Biological SciencesJanuary 1, 2026Xu Wu, Hui Gao, Qianfeng Zhuang, Feng Li, Xingliang Feng, Naiyuan Shao, Wei Zhang, Yuyang Zhang, Xiansheng ZhangTechnology, 1:1000; HPA030559, Sigma,1:1000), UFSP2 (16999-1-AP, Proteintech, 1:1000), and EEF1A1 (2551, Cell Signaling Technology,1:1000). Apoptosis assays To examine cellular apoptosis levels, cells were

(2) Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signalingThe EMBO JournalApril 22, 2025Ashley Segura-Roman, Y Rose Citron, Myungsun Shin, Nicole Sindoni, Alex Maya-Romero, Simon Rapp, Claire Goul, Joseph D Mancias, Roberto Zoncu(D1D5)(#13901), V5 rabbit (#13202), V5 mouse (#80076), SQSTM1/p62 (#397749), PP2AA (#2041), HOP (#5670), eEF1A (#2551), CACYBP (#3354), HSP90 (#4874), CCT2 (#3561), PSMA2 (#11864), PP2AC (#2259), GPI (#57893), GSK3β (#12456),

(3) Seryl‐ tRNA synthetase inhibits Wnt signaling and breast cancer progression and metastasisThe FASEB JournalJanuary 15, 2025Lei Jiang, Justin Wang, Ze Liu, Qian Zhang, Xiang‐Lei Yangantibody (#3195), anti-β-catenin antibody (#8480), anti-LysRS antibody (#5341), anti-eEF1A antibody (#2551), and anti-β-actin antibody (#4967) were purchased from Cell Signaling Technology (Danvers, MA, USA).

(4) METTL13 facilitates cell growth and metastasis in gastric cancer via an eEF1A/HN1L positive feedback circuitJournal of cell communication and signalingMarch 1, 2023Wu Q, Hu Q, Hai Y, Li Y, Gao Y.antibodies used in this study are as follows: METTL13 (#ab186002, Abcam), HN1L (#ab200571, Abcam), eEF1A (#2551, Cell Signaling Technology), β-actin (#81178, Santa Cruz Biotechnology). Cellular proliferation assay To

(5) The Legionella pneumophila Metaeffector Lpg2505 (MesI) Regulates SidI-Mediated Translation Inhibition and Novel Glycosyl Hydrolase ActivityInfection and immunityApril 20, 2020Joseph AM, Pohl AE, Ball TJ, Abram TG, Johnson DK, Geisbrecht BV, Shames SR.nonfat milk powder dissolved in Tris-buffered saline-0.1% Tween 20 [TBST]). Primary antibodies (␣-eEF1A [no. 2551S; Cell Signaling Technology], ␣-Flag-M2 [Sigma], or ␣-CyaA [3D1; no. EG800; Kerafast]) were used at 1:1,000

(6) An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanningeLifeDecember 2, 2019Díaz-López I, Toribio R, Berlanga JJ, Ventoso I.St. John´s lab,), anti-eIF3g (STJ23512, St. John´s lab), anti-EGFP (11814460001, Roche), anti-eEF1A1 (2551, Cell Signaling), anti-AKT1 (9272, Cell Signaling), anti-ACTB (T-5168, Sigma), anti-eIF4b (sc-376062,

(7) DDX39 promotes hepatocellular carcinoma growth and metastasis through activating Wnt/β-catenin pathwayCell Death & DiseaseJune 1, 2018Tong Zhang, Zhenjiang Ma, Lijuan Liu, Jian Sun, Hui Tang, Bing Zhang, Ying Zou, Heping LiBioTECH) was used, the antibodies against β-catenin (#8480, Cell Signaling Technology) and EF-1α (#2551, Cell Signaling Technology) were used. Vectors and infection Full-length human DDX39 cDNA was subcloned

(8) Unraveling the in vitro antitumor activity of Vismia baccifera against HepG2: role of hydrogen peroxideHeliyonJune 1, 2018Trepiana J, Ruiz-Larrea MB, Ruiz-Sanz JI.

(9) A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescencePLOS Computational BiologyDecember 4, 2017Patrick Meyer et al.

(10) Inhibition of group-I metabotropic glutamate receptors protects against prion toxicityPLoS pathogensNovember 1, 2017Goniotaki D, Lakkaraju AKK, Shrivastava AN, Bakirci P, Sorce S, Senatore A, Marpakwar R, Hornemann S, Gasparini F, Triller A, et al.

(11) Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retinaScientific reportsMay 13, 2016Baleriola J, Álvarez-Lindo N, de la Villa P, Bernad A, Blanco L, Suárez T, de la Rosa EJ.

(12) Comparative genomic analysis of multiple strains of two unusual plant pathogens: Pseudomonas corrugata and Pseudomonas mediterraneaFrontiers in MicrobiologyAugust 7, 2015Emmanouil A. Trantas, Grazia Licciardello, Nalvo F. Almeida, Kamil Witek, Cinzia P. Strano, Zane Duxbury, Filippos Ververidis, Dimitrios E. Goumas, Jonathan D. G. Jones, David S. Guttman, et al.clusters,2033,2051,2046,2053,2037,2039,2026,2026,2039 KOG clusters,841,841,852,852,837,839,840,845,839 Pfam clusters,2601,2566,2551,2597,"2,547","2,551","2,577","2,547","2,550" TIGRfam clusters,1345,1362,1355,1369,1369,1372,1365,1362,1372 Short

(13) Local Protein Synthesis Mediates a Rapid Increase in Dendritic Elongation Factor 1A after Induction of Late Long-Term PotentiationJournal of NeuroscienceJune 15, 2005Panayiotis Tsokas, Elizabeth A Grace, Pokman Chan, Tao Ma, Stuart C Sealfon, Ravi Iyengar, Emmanuel M Landau, Robert D Blitzer

(14) Pharmacology of Acetylcholine-Mediated Cell Signaling in the Lateral Line Organ Following Efferent StimulationJournal of NeurophysiologyMay 1, 2005Rosie Dawkins, Sarah L. Keller, William F. Sewell9. NIH-PA Author Manuscript Published in final edited form as: J Neurophysiol. 2005 May ; 93(5): 2541–2551. Pharmacology of Acetylcholine-Mediated Cell Signaling in the Lateral Line Organ Following Efferent

(15) BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryoGenes & DevelopmentAugust 1, 2004Susana M. Chuva de Sousa Lopes, Bernard A.J. Roelen, Rui M. Monteiro, Roul Emmens, Herbert Y. Lin, En Li, Kirstie A. Lawson, Christine L. Mummeryserine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. Development 126: 2551–2561. Gualdi, R., Bossard, P., Zheng, M., Hamada, Y., Coleman, J.R., and Zaret, K.S. 1996. Hepatic specification

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eEF1A Antibody

eEF1A Antibody from Cell Signaling Technology

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Cell Signaling Technology

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eEF1A Antibody from Cell Signaling Technology

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