Mouse M-CSF R/CD115 Antibody AF3818 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse M-CSF R/CD115 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF3818
ApplicationsFlow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
HostSheep
Quantity100 ug (also 25 ug)
ReactivityMouse,Transgenic Mouse
IsotypeIgG
TargetM-CSF R/CD115
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ClonalityPolyclonal
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
NCBI Gene AliasesFim2, Csfmr, CD115, M-CSFR, M-CSF-R, Fms, Fim-2, CSF-1R
NCBI Full Gene Namecolony stimulating factor 1 receptor
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse M-CSF R/CD115, Ala20-Ser511, Accession # P09581
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A strategy of microglia replacement alleviates microgliopathy in a CSF1R I794T hotspot mutation mouse model of CSF1R-related disorderCell Reports MedicineMarch 17, 2026Xin Li, Banglian Hu, Chujun Wu, Ziwei Wang, Hanzheng Fan, Xiaoyan Guan, Sulan Xie, Dadian Chen, Xiaohua Huang, Hao Sun, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Anti-GAPDH antibody,Abcam,Cat. #ab8245; RRID: AB_2630358RRID: AB_2630358 Anti-CSF1R,R&D Systems,Cat. #AF3818; RRID: AB_884158 Iba1/AIF-1 (E4O4W) XP® Rabbit mAb (17198),Cell Signaling Technology,Cat. #17198S;

(2) MiR-34a deficiency enhances nucleic acid sensing and type I IFN signaling in a mouse model of Alzheimer’s diseaseFrontiers in ImmunologyFebruary 24, 2026Junling Yang, George Elliot Tsourdinis, Charlotte Holas, Mark Maienschein-Cline, Robert Lalonde, Ken-ichiro Fukuchiagainst IFITM3 (1:1000; Abcam Cat# ab15592, RRID: AB_2122095), CSF1R (1:1000; R and D Systems Cat# AF3818, RRID: AB_884158), and GAPDH (1:5000; Millipore Cat# MAB374, RRID: AB_2107445). After three washes in

(3) Identification of novel macrophages and bone morphogenetic protein signals causing ectopic calcification and impairing muscle regenerationiScienceJuly 18, 2025Shi L, He Z, Hiraga T, Liu Z, Yamashita T, Iwamoto R, Mizoguchi T, Nakamichi Y, Kubota Y, Udagawa N, et al.rabbit monoclonal [D4C8V] (30325s, Cell Signaling Technology, 1:400), anti-Csf1r sheep polyclonal (AF3818, R&D Systems, 1:100), anti-CD68 rat monoclonal [FA-11] (14-0681-82, Invitrogen, 1:100), anti-Pax7 rabbit

(4) Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)Journal of neuroinflammationMay 31, 2023Li X, Hu B, Guan X, Wang Z, Zhou Y, Sun H, Zhang X, Li Y, Huang X, Zhao Y, et al.

(5) Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factorImmunityDecember 14, 2021Czepielewski RS, Erlich EC, Onufer EJ, Young S, Saunders BT, Han YH, Wohltmann M, Wang PL, Kim KW, Kumar S, et al.

(6) RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosisCell reportsMay 11, 2021Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, LaMorte M, Gruber R, Keane A, Loring P, et al.serum/0.2% PBT for 1 hour. Cells were incubated in the primary antibodies CSF1R (1:100; R&D Systems #AF3818), MBP (1:500; Biorad #MCA409S) and Olig2 (1:500; EMD Millipore #AB9610) diluted in 5% donkey serum/0.2%

(7) RANKL/OPG ratio regulates odontoclastogenesis in damaged dental pulpScientific reportsFebruary 25, 2021Nishida D, Arai A, Zhao L, Yang M, Nakamichi Y, Horibe K, Hosoya A, Kobayashi Y, Udagawa N, Mizoguchi T.

(8) Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer's diseaseAlzheimer's research & therapyJanuary 5, 2021Pons V, Lévesque P, Plante MM, Rivest S.

(9) Peripheral nerve resident macrophages share tissue-specific programming and features of activated microgliaNature communicationsMay 21, 2020Wang PL, Yim AKY, Kim KW, Avey D, Czepielewski RS, Colonna M, Milbrandt J, Randolph GJ.

(10) Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor GrowthCell reportsMay 19, 2020Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, Kar G, Vento-Tormo R, Hagai T, Chen X, et al.RRID:AB_1102554" Rat CXCR4,R & D Systems,"Cat# MAB21651, RRID:AB_2261636" Sheep CSFR1,R & D Systems,"Cat# AF3818, RRID:AB_884158" Rabbit CSF1,ABGENT,ABO12249 Rabbit NG2,abcam,"Cat# ab83178, RRID:AB_10672215" Rat

(11) Embryonic microglia influence developing hypothalamic glial populationsJournal of neuroinflammationMay 6, 2020Marsters CM, Nesan D, Far R, Klenin N, Pittman QJ, Kurrasch DM.

(12) Role of Macrophage Colony-Stimulating Factor Receptor on the Proliferation and Survival of Microglia Following Systemic Nerve and Cuprizone-Induced InjuriesFrontiers in immunologyJanuary 1, 2020Pons V, Laflamme N, Préfontaine P, Rivest S.1:1,000; WAKO Chemical 019-19741), or with the primary antibody anti-CSF1R (sheep, 1:500; R&D System AF3818), or with the primary antibody Tmem119 (rabbit, 1:1,000; ABCAM ab209064). After washing the sections

(13) Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized InvasionFrontiers in oncologyJanuary 1, 2020Ibrahim AM, Moss MA, Gray Z, Rojo MD, Burke CM, Schwertfeger KL, Dos Santos CO, Machado HL.and stained with antibodies that detect Lyve-1 (1:60 R&D Systems, AF2125), CSFR1 (1:15 R&D Systems, AF3818), CD206 (1:1000, Abcam ab64693), and Gas6 (1:200 R&D Systems, AF986) at 4◦ C overnight. Slides were stained

(14) Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survivalJournal of immunology (Baltimore, Md. : 1950)June 15, 2008Melcher M, Unger B, Schmidt U, Rajantie IA, Alitalo K, Ellmeier W.with ice-cold PBS, and incubated with 3 ml of PBS containing 6 ␮g/ml sheep anti-M-CSFR Ab (catalog no. AF3818, R&D Systems) specific for the extracellular domain of the M-CSFR for 15 min at 4°C. Unbound Ab was

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M-CSF R/CD115 Antibody

M-CSF R/CD115 Antibody

Mouse M-CSF R/CD115 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (14)

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Mouse M-CSF R/CD115 Antibody from R&D Systems, a Bio-Techne Brand

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