insulin Rβ (CT-3) Antibody sc-57342 from Santa Cruz Biotechnology, Inc.

Product Specs
Iteminsulin Rβ (CT-3) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-57342
NCBI Gene AliasesIR-B, IR-A, D630014A15Rik, IR, CD220, HHF5, 4932439J01Rik
Antibody TypePrimary Antibodies
Quantity200 µg/ml
CloneCT-3
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, IHC(P)
Hostmouse
Conjugate/TagUnconjugated
ClonalityMonoclonal
FormatPurified
NCBI Full Gene Nameinsulin receptor
Targetinsulin receptor
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Mutation in IR or IGF1R produces features of long-lived mice while maintaining metabolic healthJCI InsightDecember 22, 2025Ulalume Hernández-Arciga, Jun Kyoung Kim, Jacob L. Fisher, Alexander Tyshkovskiy, Alibek Moldakozhayev, Catherine Hall, Souvik Ghosh, Yashvandhini Govindaraj, Ian J. Sipula, Jake Kastroll, et al.included anti-IR-pY1150/1151 (1:2000; 19H7, Cell Signaling, 3024), anti-IR (1:500; CT-3, Santa Cruz, sc-57342), anti-IGF-1R (1:1000; ZI001, Invitrogen, 39-6700), anti-AKT (1:2000; 40D4, Cell Signaling, 2920), anti-pS473

(2) Role of the Insulin Receptor in Mediating Cytosolic Delivery of Proteins by a Modified Cell-Penetrating PeptidePharmaceuticals (Basel)December 12, 2025Keito Sugai, Akiko Okudaat 4 °C with primary antibodies against IGF1R (3B7, sc-462; Santa Cruz Biotechnology) or INSR (CT3, sc-57342; Santa Cruz Biotechnology) diluted 1:200 in Immuno Shot 1 solution; washed; and incubated at room temperature

(3) Tuning insulin receptor signaling using de novo-designed agonistsMolecular CellNovember 6, 2025Xinru Wang, Sarah Cardoso, Kai Cai, Preetham Venkatesh, Albert Hung, Michelle Ng, Catherine Hall, Brian Coventry, David S. Lee, Rishabh Chowhan, et al.#2434), anti-Myc (1:2000; 9E10, Roche; labeled as IR, #11667149001), anti-IR (1:500; CT3, Santa Cruz, sc-57342), anti-AKT (WB, 1:2000; 40D4, #2920), anti-pS473 AKT (WB, 1:2000; D9E, #4060), anti-ERK1/2 (WB, 1:2000;

(4) Oral lipoteichoic and lipoic acids improve insulin resistance and body composition in porphyria mice on a high-carbohydrate dietJournal of Physiology and BiochemistrySeptember 26, 2025Miriam Longo, Teresa Rubio, Araceli Lamelas, Daniel Jericó, Andrea Rodenes-Gavidia, Jordi Cervero, Juan Martínez-Blanch, Empar Chenoll, Patricia Martorell, Erika Paolini, et al.Santa Cruz Biotechnology, Heidelberg, Germany), anti-Glut4 (sc-53566, Santa Cruz Biotechnology), anti-InsRβ (sc-57342, Santa Cruz Biotechnology), and anti-Vinculin (EPR8185, abcam, Cambridge, UK). Fecal microbiota Stool

(5) Exploring multiorgan mitochondrial dysfunction in the switch toward progressive MASLD in AMLN miceiScienceSeptember 19, 2025Meroni M, Paolini E, Longo M, Battistin M, Dondossola D, Ripolone M, Napoli L, Mosca E, Corti S, Dongiovanni P.CD7E7), WB",Cell Signaling,Cat#4691; RRID: AB_915783 "Mouse monoclonal InsR antibody, WB",Santa Cruz,Cat#sc-57342; RRID: AB_784102 Rabbit monoclonal Anti-Vinculin antibody [EPR8185],Abcam,Cat#AB129002; RRID: AB_11144129 Mouse

(6) Intracerebroventricular insulin injection acutely normalizes the augmented exercise pressor reflex in male rats with type 2 diabetes mellitusThe Journal of PhysiologySeptember 1, 2025Juan A. Estrada, Rie Ishizawa, Han‐Kyul Kim, Ayumi Fukazawa, Amane Hori, Norio Hotta, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, Masaki Mizunoantibody, 1:1000, cat. no. 4292, RRID#AB_329869, CST; mouse anti‐IR β monoclonal antibody, 1:1000, cat. no. sc‐57342, RRID#AB_784102, Santa Cruz Biotechnology (SCBT), Dallas, TX, USA; mouse anti‐β‐actin monoclonal antibody,

(7) Silicon-enriched meat consumption mitigates brain cortex damage associated with diabetic dyslipidemia in a late-stage type 2 diabetes mellitus rat modelRedox BiolMay 31, 2025Rocío Redondo-Castillejo, Luis Apaza Ticona, Adrián Macho-González, Aránzazu Bocanegra, Alba Garcimartín, Marina Hernández-Martín, Anastasia Parfenova, Sara Bastida, Luis García-García, M. Elvira López-Oliva, et al.sc-34282, anti-GPx sc-133160, anti-GR sc-32886, anti-GFAP sc-33673, anti-GLUT3 sc-74399, anti-InsRβ sc-57342, anti-IRS1 sc-515017, anti-pAKTser473 sc-514032, anti-AKT sc-81434, anti-pGSK3βser9 sc-373800, anti-GSK3β

(8) Kumquat Fruit Administration Counteracts Dysmetabolism-Related Neurodegeneration and the Associated Brain Insulin Resistance in the High-Fat Diet-Fed MiceInternational Journal of Molecular SciencesMarch 27, 2025Alessandro Massaro, Pasquale Calvi, Ignazio Restivo, Marta Giardina, Flavia Mulè, Luisa Tesoriere, Antonella Amato, Domenico Nuzzo, Pasquale Picone, Simona Terzo, et al.4,"Invitrogen(Milan, Italy)",PA1-036,Rabbit,130 kDa InsR-β 5,"Santa Cruz Biotechnologies(Milan, Italy)",SC-57342,Mouse,95 kDa pSer307-IRS1 6,"Merck(Milan, Italy)",SAB4504442,Rabbit,131 kDa NF-κB 7,"Santa Cruz Biotechnologies(Milan,

(9) Insulin receptor responsiveness governs TGFβ-induced hepatic stellate cell activation: Insulin resistance instigates liver fibrosisFASEB JMarch 15, 2025Wang-Hsin Lee, Evelyn A. Bates, Zachary A. Kipp, Sally N. Pauss, Genesee J. Martinez, Cheavar A. Blair, Terry D. Hindsblocking, the membranes were incubated with primary antibodies against the insulin receptor (Santa Cruz SC‐57342, 1:1000, in TBS) and heat shock protein 90 (HSP90) (R&D AF3776, 1:1000, in TBS) at 4°C overnight. Subsequently,

(10) Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomasCell Commun SignalMarch 4, 2025Rosa Catalano, Emma Nozza, Barbara Altieri, Emanuela Esposito, Giorgio A. Croci, Anna Maria Barbieri, Donatella Treppiedi, Sonia Di Bari, Otilia Kimpel, Mario Detomas, et al.CH; prediluted, EDTA buffer retrieval, #790–4346) and anti-IR (CT-3 clone, Santa Cruz Biotechnology, #sc-57342, RRID: AB_784102, CA, USA; 1:100, Citrate buffer retrieval) antibodies was performed using an automated

(11) Optogenetic control of Protein Kinase C-epsilon activity reveals its intrinsic signaling properties with spatiotemporal resolutionbioRxivJanuary 6, 2025Qunxiang Ong, Crystal Jing Yi Yi Lim, Yilie Liao, Justin Tze-Yang Tze-Yang Ng, Ler Ting Rachel Rachel Lim, Shernys Xuan Yi Yi Koh, Sher En En Chan, Pheobe Yu Ying Yu Ying, Huijun Lim, Chen Rui Ye, et al.,Cell Signalling Technology,#2261 Insulin Rb antibody (C-19) polyclonal anti-rabbit,Santa Cruz Biotechnology,sc-57342 Phospho-IRK (T1150/T1151) monoclonal anti-mouse,Sigma Aldrich,04–299 Phospho-IRK (T1163/1162/1158)

(12) Beta‐Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5Advanced ScienceApril 1, 2024Lu Ding, Yang Sun, Yan Liang, Jie Zhang, Zhendong Fu, Caiyue Ren, Pengfei Li, Wen Liu, Rong Xiao, Hao Wang, et al.(#2535S, CST), AKT (#ab18785, abcam), p‐AKT (S473) (#4058s, CST), p‐AKT (T308) (#13038S, CST), IR (#sc57342, Santa Cruz Biotechnology), p‐IR (Tyr1150/1151) (#sc‐81500, Santa Cruz Biotechnology), Caspase 3 (#14

(13) Activation of the insulin receptor by insulin-like growth factor 2Nat CommunMarch 23, 2024Weidong An, Catherine Hall, Jie Li, Albert Hung, Jiayi Wu, Junhee Park, Liwei Wang, Xiao-Chen Bai, Eunhee Choianti-Myc (1:2000; 9E10, Roche; labeled as IR, Cat. #11667149001), anti-IR (1:500; CT3, Santa Cruz, Cat. #sc-57342), anti-AKT (WB, 1:2000; 40D4, Cat. #2920), anti-pS473 AKT (WB, 1:2000; D9E, Cat. #4060), anti-ERK1/2

(14) Deep proteomic analysis of obstetric antiphospholipid syndrome by DIA-MS of extracellular vesicle enriched fractionsCommunications biologyJanuary 15, 2024Tian W, Shi D, Zhang Y, Wang H, Tang H, Han Z, Wong CCL, Cui L, Zheng J, Chen Y.anti-Annexin A2(1:7000)(ANXA2), ab178677 (Abcam); anti-VWF(1:1000), 65707 (CST); anti-INSR(1:200), sc57342 (Santa Cruz Biotechnology); anti-Calnexin(1:1000), ab22595 (Abcam); anti-TOM20(1:1000), 11802-1-AP (Proteintech);

(15) Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic mannerNature communicationsDecember 9, 2023González-Vila A, Luengo-Mateos M, Silveira-Loureiro M, Garrido-Gil P, Ohinska N, González-Domínguez M, Labandeira-García JL, García-Cáceres C, López M, Barca-Mayo O.(dilution 1:1000); CRY1 (Invitrogen, PA5-89349) (dilution 1:1000); IRβ (CT-3) (Santa Cruz Biotechnology, sc-57342) (dilution 1:500); UCP1 (Abcam, ab10983) (dilution 1:1000); phospho-mTOR (Cell Signaling, 2971-S) (dilution

(16) Blockade of endogenous insulin receptor signaling in the nucleus tractus solitarius potentiates exercise pressor reflex function in healthy male ratsFASEB journal : official publication of the Federation of American Societies for Experimental BiologySeptember 1, 2023Estrada JA, Hotta N, Kim HK, Ishizawa R, Fukazawa A, Iwamoto GA, Smith SA, Vongpatanasin W, Mizuno M.Cell Signaling Technology, Danvers, MA, USA; mouse anti-insulin receptor β monoclonal antibody, 1:100, cat. no. sc-57342, RRID#AB_784102, Santa Cruz Biotechnology, Dallas, TX, USA) diluted in antibody buffer. We previously

(17) Brain insulin signaling suppresses lipolysis in the absence of peripheral insulin receptors and requires the MAPK pathwayMolecular metabolismJuly 1, 2023Metz M, O'Hare J, Cheng B, Puchowicz M, Buettner C, Scherer T.primary antibodies in 1:1 Blocking Buffer/TBS-T overnight at 4 °C. Primary antibodies against IRβ (sc-57342, Santa Cruz Biotechnology, Santa Cruz, CA), Glut 4 (ab654, Abcam, Cambridge UK), Akt (#9272), phos Akt

(18) BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptidesMolecular neurodegenerationMay 4, 2023Zhou J, Singh N, Galske J, Hudobenko J, Hu X, Yan R.(B-5),sc-5289,AB_673566,Santa Cruz CXCL14,ab137541,,Abcam IRα,sc-57344,AB_782041,Santa Cruz IRβ (CT-3),sc-57342,AB_784102,Santa Cruz Jun (60A8),9165,AB_2130165,Cell Signaling P38 (D13E1),8690,AB_10999090,Cell Signaling pP38

(19) Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD MiceAntioxidants (Basel, Switzerland)March 15, 2023Han S, He Z, Hu X, Li X, Zheng K, Huang Y, Xiao P, Xie Q, Ni J, Liu Q.(Cat#64099) were purchased from Cell Signaling Technology, Inc., Boston, MA, USA. Antibodies against IR (Cat#sc-57342), p-IR-Tyr1150 (Cat#sc-81500), and ACSL4 (Cat#sc-271800) were purchased from Santa Cruz Biotechnology, Inc

(20) SerpinA3N deficiency attenuates steatosis and enhances insulin signaling in male miceThe Journal of endocrinologyMarch 1, 2023Tran M, Mostofa G, Picard M, Wu J, Wang L, Shin DJ.(sc-365513, Santa Cruz Biotechnology Inc.), Tyr1162/Tyr1163 p-IRβ (44-804G, Thermo Fisher Scientific), IRβ (sc-57342, Santa Cruz Biotechnology Inc.), Ser473 p-AKT (4060, Cell Signaling Technology, Danvers, MA), AKT (9272,

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insulin Rβ (CT-3) Antibody

insulin Rβ (CT-3) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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insulin Rβ (CT-3) Antibody from Santa Cruz Biotechnology, Inc.

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