caspase-4 (4B9) Antibody sc-56056 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemcaspase-4 (4B9) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-56056
NCBI Gene AliasesMih1/TX, TX, ICH-2, ICE(rel)II, Mih1, ICEREL-II
Antibody TypePrimary Antibodies
Clone4B9
Quantity100 µg/ml
ApplicationsWB, IP
Reactivityhuman
Hostmouse
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
NCBI Full Gene Namecaspase 4
Targetcaspase-4
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Unfolding Immune Dysregulation in COPD: Identification of a Three-Gene Signature and Functional Validation of TCF7 in Human Lung Tissue and T LymphocytesInt J Mol SciMay 9, 2026Zengrui Wang, Yue Yang, Le Wang, Zhuang Luoanti-TCF7 (same as above) andmouse anti-caspase-8 (Santa Cruz Biotechnology, Dallas, TX, USA; Cat. No. sc-56056). After washing, sections were incubated with Alexa Fluor 488-conjugated anti-mouse (green; Invitrogen,

(2) Differential targeting of human pyroptotic caspase-5 and caspase-4 by Shigella OspC2 and OspC3mBioMarch 11, 2026Kyungsub Kim, Marcos Antonio Valdespino Diaz, Rowan M. Karr, Michele E. Muscolo, Lisa Goers, Truelian Yu, Tera C. Levin, Jonathan N. Pruneda, Cammie F. LesserKnockouts were verified by immunoblotting lysates with anti-CASP4 antibody (Santa Cruz, clone 4B9, sc-56056). Gentamicin/chloroquine protection assay HeLa cells seeded in 96-well plates (2 × 104 cells per well)

(3) Dual NLRC4 and non-canonical inflammasome signaling drives human GSDMD-mediated killing of Shigella flexneri independently of bacterial cardiolipinbioRxivJanuary 14, 2026Mateusz Szczerba, Marcia B. Goldberg(1:1000), GBP1 (Abcam, ab131255) rabbit monoclonal antibody at 0.25 μg/mL (1:5000), caspase-4 (Santa Cruz, sc-56056) and GSDMD (Santa Cruz, sc-81868) mouse monoclonal antibodies at 0.5 μg/mL (1:200). Secondary antibodies

(4) Pyroptosis of periodontal ligament stem cells aggravates periodontitis via Piezo1 channeliScienceMay 16, 2025Peng Chen, Duo Liu, Yi-kun Zhou, Jiu-hui Jiang, Rui-li Yang,Santa Cruz Biotechnology,Cat# sc-56038; RRID:AB_781818 Mouse monoclonal anti-caspase 4,Santa Cruz Biotechnology,Cat# sc-56056; RRID:AB_781828 Mouse monoclonal anti-CD90,Santa Cruz Biotechnology,Cat# sc-53116; RRID:AB_630310 Mouse

(5) NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteriamBioMay 14, 2025Mateusz Szczerba, Akshaya Ganesh, María Luisa Gil-Marqués, Volker Briken, Marcia B. Goldbergcaspase-1 (Abcam, ab207802), rabbit monoclonal antibody at 0.5 µg/mL (1:1,000), caspase-4 (Santa Cruz, sc-56056), and GSDMD (Santa Cruz, sc-81868) mouse monoclonal antibodies at 0.5 µg/mL (1:200). Secondary antibodies

(6) Potent Ameliorative Effects of Rosmarinic Acid on Tramadol-Induced Neurotoxicity in the Brain and Hippocampus; by Suppressing Oxidative stress, Apoptosis, ER stress, and Regulating Cognitive FunctionsMolecular NeurobiologyApril 7, 2025Onur Karaca, Hasan Şimşek, Nurhan Akaras, Cihan Gür, Mustafa İleritürk, Özge Kandemir, Sefa Küçükler, Şeyda Öte Karaca, Fatih Mehmet Kandemiracidic protein (GFAP) (Santa Cruz, Sc-33673) and cysteine–aspartic acid protease 3 (Casp-3) (Santa Cruz, Sc-56056). GFAP and Casp-3 immunopositivity were scored as follows: no change, ( −), mild change ( +), moderate

(7) NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteriabioRxivMarch 7, 2025Mateusz Szczerba, Akshaya Ganesh, María Luisa Gil-Marqués, Volker Briken, Marcia B. Goldbergcaspase-1 (Abcam, ab207802) rabbit monoclonal antibody at 0.5 μg/mL (1:1000), caspase-4 (Santa Cruz, sc-56056) and GSDMD (Santa Cruz, sc-81868) mouse monoclonal antibodies at 0.5 μg/mL (1:200). Secondary antibodies

(8) Carbon nanotubes conjugated with cisplatin activate different apoptosis signaling pathways in 2D and 3D-spheroid triple-negative breast cancer cell cultures: a comparative studyArchives of ToxicologySeptember 1, 2024Madalina Andreea Badea, Mihaela Balas, Daniela Ionita, Anca DinischiotuSanta Cruz), anti-caspase-8 (sc-5263, Santa Cruz), anti-caspase-9 (sc-56076, Santa Cruz), and anti-caspase-4 (sc-56056, Santa Cruz). On the next day, membranes were washed with wash solutions and incubated with anti-mouse

(9) Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasomemSphereOctober 24, 2023Abby R. Kroken, Keith A. Klein, Patrick S. Mitchell, Vincent Nieto, Eric J. Jedel, David J. Evans, Suzanne M. J. FleiszigMembrane was blocked with Bio-Rad EveryBlot block and probed with anti-caspase-4 antibody (Santa Cruz, sc-56056, 1:1000). Blot was washed using Tris-buffered saline with 0.1% Tween-20, and the antibody was detected

(10) Cytosolic LPS-induced caspase-11 oligomerization and activation is regulated by extended synaptotagmin 1Cell reportsJuly 25, 2023Ma Y, Zhao R, Guo H, Tong Q, Langdon WY, Liu W, Zhang J, Zhang J.anti-Caspse-1 p10,Santa Cruz,Cat# sc-514; RRID:AB_2068895 Mouse monoclonal anti-Caspse-4,Santa Cruz,Cat# sc-56056; RRID:AB_781828 Mouse monoclonal anti-IL-1β,Santa Cruz,Cat# sc-32294; RRID:AB_627790 Rat monoclonal

(11) NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophagesScience immunologyJuly 21, 2023Rojas-Lopez M, Gil-Marqués ML, Kharbanda V, Zajac AS, Miller KA, Wood TE, Hachey AC, Egger KT, Goldberg MB.

(12) Glycolysis Aids in Human Lens Epithelial Cells' Adaptation to HypoxiaAntioxidants (Basel, Switzerland)June 19, 2023Huang Y, Ping X, Cui Y, Yang H, Bao J, Yin Q, Ailifeire H, Shentu X.anti-XBP1 (sc-8015, Santa Cruz Biotechnology), anti-CASP3 (sc-7272, Santa Cruz Biotechnology), anti-CASP4 (sc-56056, Santa Cruz Biotechnology), anti-CASP9 (sc-56076, Santa Cruz Biotechnology), anti-CYCS (11940, CST),

(13) Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasomebioRxivMay 4, 2023Abby R Kroken, Keith A Klein, Patrick S Mitchell, Vincent Nieto, Eric J Jedel, David J Evans, Suzanne M J FleiszigMembrane was blocked with Bio-Rad EveryBlot block and probed with anti-caspase-4 antibody (Santa Cruz, sc-56056, 1:1000). Blot was washed using TBST, and antibody detected with goat-anti-rabbit HRP (Bio-Rad, 1706515,

(14) Klebsiella pneumoniae Induces Inflammatory Bowel Disease Through Caspase-11-Mediated IL18 in the Gut Epithelial CellsCellular and molecular gastroenterology and hepatologyJanuary 1, 2023Zhang Q, Su X, Zhang C, Chen W, Wang Y, Yang X, Liu D, Zhang Y, Yang R.14340 Anti-LPS,Abcam,Cat: ab35654 RRID:AB_732222 Anti-human caspase-4 (4B9),Santa Cruz Biotechnology,Cat: sc-56056 RRID:AB_781828 Anti-mouse/human NLRP3 (EPR23094-1),Abcam,Cat: ab263899 RRID:AB_2889890 Anti-mouse/human

(15) Double-Edged Sword Effect of Pyroptosis: The Role of Caspase-1/-4/-5/-11 in Different Levels of Apical PeriodontitisBiomoleculesNovember 8, 2022Zhiwu Wu, Mingming Li, Xiaolin Ren, Rui Zhang, Jinfeng He, Li Cheng, Ran Cheng, Tao Huantibodies overnight at 4 °C: anti-caspase-1 (sc-398715, Santa Cruz Biotechnology), anti-caspase-4 (sc-56056, Santa Cruz Biotechnology), anti-caspase-5 (sc-393346, Santa Cruz Biotechnology), anti-GADMD-N (ab215203,

(16) Human neutrophil IL1β directs intestinal epithelial cell extrusion during Salmonella infectionPLoS pathogensOctober 1, 2022Lawrence AE, Berger RP, Hill DR, Huang S, Yadagiri VK, Bons B, Fields C, Sule GJ, Knight JS, Wobus CE, et al.(Li-Cor Biosciences). The following antibodies were used: anti-Caspase-4 antibody (4B9) (Santa Cruz, Cat# sc-56056), anti-Caspase-5 (D3G4W) antibody (Cell Signaling, Cat#46680), IRDye 800CW Goat anti-Mouse IgG antibody

(17) Caspase-4/11 is critical for angiogenesis by repressing Notch1 signalling via inhibiting γ-secretase activityBritish journal of pharmacologyOctober 1, 2022Fan L, Liu H, Zhu G, Singh S, Yu Z, Wang S, Luo H, Liu S, Xu Y, Ge J, et al.

(18) Expression of human caspase-4 in the gingival epithelium affected with periodontitis: Its involvement in Porphyromonas gingivalis-challenged gingival epithelial cellsArchives of oral biologyAugust 1, 2022Kantrong N, Buranaphatthana W, Hormdee D, Suwannarong W, Chaichit R, Pattanaporn K, Klanrit P, Krisanaprakornkit S.

(19) Mitochondrial calpain-5 truncates caspase-4 during endoplasmic reticulum stressBiochemical and biophysical research communicationsJune 11, 2022Chukai Y, Ito G, Konno M, Sakata Y, Ozaki T.

(20) Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling PathwayOxidative medicine and cellular longevityJanuary 1, 2022Zhang B, Wan S, Liu H, Qiu Q, Chen H, Chen Z, Wang L, Liu X.(26593-1-AP, 1 : 2000, Proteintech Group), Nrf2 (16396-1-AP, 1 : 5000, Proteintech Group), caspase-4 (sc-56056, 1 : 200, Santa Cruz), NLRP3 (#15101, 1 : 1000, Cell Signaling Technology), caspase-11 (sc-56038, 1 : 400

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caspase-4 (4B9) Antibody

caspase-4 (4B9) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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caspase-4 (4B9) Antibody from Santa Cruz Biotechnology, Inc.

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