SMAC/Diablo Antibody

Product Specs
ItemSMAC/Diablo Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $339.00Supplier Page View Company Product Page
Catalog NumberNB100-56311
Concentration0.5 mg/ml
ImmunogenThis rabbit polyclonal antibody was developed against two synthetic peptides corresponding to amino acids 199 to 212 and amino acids 226 to 239 of human Smac (Genbank accession no. AAF87716)
NCBI Gene AliasesSMAC, DFNA64
ReactivityHuman,Mouse
Conjugate/TagUnconjugated
Quantity0.1 mg (also 0.025 mg)
TargetSMAC/Diablo
HostRabbit
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
FormatPBS
NCBI Full Gene Namediablo IAP-binding mitochondrial protein
ClonalityPolyclonal
PurityProtein G purified
IsotypeIgG
Antibody TypePrimary Antibodies
Research AreaApoptosis, Cancer, Cell Biology, Cellular Markers, Mitochondrial Markers, Tumor Suppressors
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 mg (also 0.025 mg)

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

(1) Activation of dual apoptotic pathways in human melanocytes and protection by survivinThe Journal of investigative dermatologyJanuary 1, 0001"Liu T, Biddle D, Hanks AN, Brouha B, Yan H, Lee RM, Leachman SA, Grossman D."

(2) Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cellsCancer researchJanuary 1, 0001"Qin JZ, Ziffra J, Stennett L, Bodner B, Bonish BK, Chaturvedi V, Bennett F, Pollock PM, Trent JM, Hendrix MJ, et al."

(3) Immunohistochemical analysis of Smac/DIABLO expression in human carcinomas and sarcomas"APMIS : acta pathologica, microbiologica, et immunologica Scandinavica"January 1, 0001"Yoo NJ, Kim HS, Kim SY, Park WS, Park CH, Jeon H, Jung ES, Lee JY, Lee SH."

(7) 7-Ketocholesterol-induced apoptosis. Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathwaysThe FEBS journalJanuary 1, 0001"Berthier A, Lemaire-Ewing S, Prunet C, Montange T, Vejux A, Pais de Barros JP, Monier S, Gambert P, Lizard G, Néel D."

(8) Expression of Smac/DIABLO in B-cell non-Hodgkin and Hodgkin lymphomasHuman pathologyJanuary 1, 0001"Ren Y, Akyurek N, Schlette E, Rassidakis GZ, Medeiros LJ."

(9) An apoptosis-independent role of SMAC in tumor suppressionOncogeneJanuary 1, 0001"Qiu W, Liu H, Sebastini A, Sun Q, Wang H, Zhang L, Yu J."

(10) p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomasMolecular cancer therapeuticsJanuary 1, 0001"Qin JZ, Stennett L, Bacon P, Bodner B, Hendrix MJ, Seftor RE, Seftor EA, Margaryan NV, Pollock PM, Curtis A, et al."

(11) Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammationThe Journal of experimental medicineJanuary 1, 0001"Conus S, Perozzo R, Reinheckel T, Peters C, Scapozza L, Yousefi S, Simon HU."

(12) Clinical significance of Smac/DIABLO expression in colorectal cancerOncology reportsJanuary 1, 0001"Endo K, Kohnoe S, Watanabe A, Tashiro H, Sakata H, Morita M, Kakeji Y, Maehara Y."

(13) PR39 inhibits apoptosis in hypoxic endothelial cells: role of inhibitor apoptosis protein-2CirculationJanuary 1, 0001"Wu J, Parungo C, Wu G, Kang PM, Laham RJ, Sellke FW, Simons M, Li J."

(14) "Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response"Molecular cancer research : MCRJanuary 1, 0001"Liu J, Dai Q, Chen J, Durrant D, Freeman A, Liu T, Grossman D, Lee RM."

(15) Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significanceJournal of clinical oncology : official journal of the American Society of Clinical OncologyJanuary 1, 0001"Mizutani Y, Nakanishi H, Yamamoto K, Li YN, Matsubara H, Mikami K, Okihara K, Kawauchi A, Bonavida B, Miki T."

(16) SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)The Journal of biological chemistryJanuary 1, 0001"Vucic D, Deshayes K, Ackerly H, Pisabarro MT, Kadkhodayan S, Fairbrother WJ, Dixit VM."

SMAC/Diablo Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand