MRC1 Polyclonal Antibody bs-4727R from Bioss Inc.

Product Specs
ItemMRC1 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-4727R
Quantity100ul, 20uL
ApplicationsIF(IHC-P), WB, FCM, IF, WB, IHC, Others, IHC, WB, ELISA, FCM, IHC-P, IF
Concentration1ug/ul
Conjugate/TagUnconjugated
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ReactivityRat, Mouse, Dog, Human
ClonalityPolyclonal
TargetMRC1
IsotypeIgG
Molecular Weight160kDa
HostRabbit
Antibody TypePrimary Antibody
ImmunogenKLH conjugated peptide, human MRC1
NCBI Gene AliasesCLEC13D, hMR, MMR, CLEC13DL, CD206, bA541I19.1, MRC1L1
NCBI Full Gene Namemannose receptor C-type 1
TissueBrain, Lung, Liver, Bone

Questions and Answers

Can this antibody be used to study macrophage polarization in my experiments?

Yes, the MRC1 Polyclonal Antibody has been utilized in studies to analyze macrophage polarization, particularly in distinguishing between M1 and M2 phenotypes. For instance, it was used in immunohistochemistry to assess the presence of M2-like markers in various experimental models, demonstrating its relevance in macrophage studies.

What species can I use this antibody on for my research?

The MRC1 Polyclonal Antibody is reactive with several species, including human, mouse, rat, and canine. This broad reactivity allows for its application in diverse biological studies across different animal models.

Is this antibody effective for flow cytometry applications?

Yes, the MRC1 Polyclonal Antibody has been shown to work effectively in flow cytometry. It has been used to analyze macrophage surface markers, including CD206, which is critical for studying macrophage function and polarization.

How has this antibody been applied in recent research?

Recent studies have employed the MRC1 Polyclonal Antibody in various contexts, such as examining the role of macrophages in inflammation and tissue repair. For example, it was used to investigate macrophage reprogramming and its impact on osteogenesis in bone defect repair models, highlighting its utility in understanding immune responses in tissue engineering.

Bioss Inc.

300 Tradecenter Drive

Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
orders@biossusa.com
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Company Profile

Website: www.biossusa.com

(1) Bifunctional adECM bioscaffold with STIM1-ASCs and IGF-2 promotes functional masseter VML repair via myogenesis and fibrosis suppressionBioactive MaterialsDecember 1, 2025Wei Liang, Rigele Ao, Mengli Xu, Mengying Jin, Meng Han, Zimo Wang, Wanwen Dang, Hongxu Wu, Weibo Lin, Yonghuan Zhen, et al.incubated with CD80-PE antibody (1:200, 12-0800-82, eBioscience), CD206-APC (MRC1/APC) antibody (1:100, bs-4727R, Bioss), and F4/80-FITC antibody (1:200, AER-051-F, ThermoFisher) for 30 min. The cells were then washed

(2) Nicotinamide nucleotide transhydrogenase deficiency and genetic susceptibility to high glucose‐mediated peritoneal injury in micePhysiological ReportsNovember 14, 2025Margarete C. Ohse, Song Rong, Sonja Schmidt, Michael S. Balzer, Christoph Nikolin, Sibylle von Vietinghoff, Hermann Haller, Kai M. Schmidt‐Ott, Yulia Kiyan, Nelli Shushakova(Santa Cruz Technology, clone H‐11, sc‐374650), CD206 (Bioss Antibodies, Woburn, MA, USA, rabbit polyclonal, bs‐4727R), α‐SMA (Sigma‐Aldrich, clone 1A4, A5228), pan‐cytokeratin (Santa Cruz Technology, sc‐15367), and NNT

(3) Extracellular vesicles from adipose‐derived mesenchymal stem cells prevent high glucose‐induced retinal ganglion cell pyroptosis through a microRNA‐26a‐5p‐dependent mechanismJournal of Diabetes InvestigationSeptember 1, 2025Lei Tang, Jian Zhang, Jianping Gaosynthase (iNOS) (1:600, ab283655), CD86 (1:500, ab239075), Arg1 (1:60, ab233548), or CD206 (1 μg/mL, bs‐4727R; Bioss Inc., Woburn, MA, USA) at 4°C in the dark for 30 min. Subsequently, cells were re‐probed with

(4) A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repairJournal of NanobiotechnologyNovember 13, 2024Ying Wang, Yedan Chen, Tao Zhou, Jingze Li, Na Zhang, Na Liu, Pinghui Zhou, Yingji Mao105 cells. The samples were then incubated on ice in the dark for 30 min using the antibody CD206 (bs-4727R; Bioss). Finally, the cells were resuspended with 300 µL PBS and detected on a BD FACSVerse cell analyzer

(5) Areca nut-induced metabolic reprogramming and M2 differentiation promote OPMD malignant transformationJournal of experimental & clinical cancer research : CRAugust 20, 2024Yuan SF, Chan LP, Nguyen HDH, Su CW, Chen YK, Chen JY, Shimodaira S, Hu SC, Lo S, Wang YY.4% paraformaldehyde for 30 min and then stained with CD163 (ab182422, Abcam, Cambridge, UK), CD206 (bs4727R, Bioss, MA), or HLA-DR (ab175085, Abcam, Cambridge, UK) antibodies for 30 min. The fluorescence intensity

(6) Anti-Ferroptotic Treatment Deteriorates Myocardial Infarction by Inhibiting Angiogenesis and Altering Immune ResponseAntioxidants (Basel)June 26, 2024Rebecca A. Stairley, Allison M. Trouten, Shuang Li, Patrick L. Roddy, Kristine Y. DeLeon-Pennell, Kyu-Ho Lee, Henry M. Sucov, Chun Liu, Ge Tao(1:100, Cedarlane Labs, Burlington, ON, Canada, #CL8943AP), and CD206 (1:200, Bioss, Woburn, MA, USA, #bs-4727R). Secondary antibodies were all used at a dilution of 1:400 and included Thermo Invitrogen #A21200 Chicken

(7) The Effect of Pregabalin on Microglia Differentiation in Rat with Neuropathic pain: A Preliminary StudyInternational journal of medical sciencesJanuary 1, 2024Hong SW, Piao L, Cho EH, Seo EH, Kim SH.Antibodies) and mouse Iba1 were used as primary antibodies. For the M2 phenotype, rabbit CD206 (CAT No. bs-4727R; Bioss Antibodies) and mouse Iba1 were used. CD16-positive cells among those with positive DAPI were

(8) Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathwayCNS Neuroscience & TherapeuticsSeptember 1, 2023Xin Li, Huimei Shi, Di Zhang, Bei Jing, Zhenni Chen, Yachun Zheng, Shiquan Chang, Li Gao, Guoping ZhaoIBA‐1 (A5141) β‐actin (4970S), and goat anti‐rabbit IgG (H + L) HRP (E030120‐02). Anti‐rat CD206 APC (bs‐4727R) was obtained from Bioss (Beijing, China). PE anti‐mouse CD32 (Fcgr2) (156404) and APC anti‐mouse CD206 (MMR

(9) Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarizationCNS neuroscience & therapeuticsJuly 1, 2022Xue MT, Sheng WJ, Song X, Shi YJ, Geng ZJ, Shen L, Wang R, Lü HZ, Hu JG.polyclonal,bs−1305R,AB_11056896,PE,Bioss,1 μg/test Arg−1,Rabbit polyclonal,PA5‐29645,AB_2547120,,Invitrogen,1:200 CD206,Rabbit polyclonal,bs−4727R,AB_2894915,FITC,Bioss,1 μg/test iNOS,Rabbit polyclonal,PA1‐036,AB_325773,,Invitrogen,1:500 TNF‐α,Rabbit

(10) Recombinant Human Lactoferrin Reduces Inflammation and Increases Fluoroquinolone Penetration to Primary Granulomas During Mycobacterial Infection of C57Bl/6 MiceArchivum immunologiae et therapiae experimentalisFebruary 28, 2022Nguyen TKT, Niaz Z, Kruzel ML, Actor JK.(Invitrogen, ThermoFisher, Cat# 14-0381-02), diluted at 1:1000, M2-like marker CD 206 (Bioss, Cat# bs-4727R), diluted at 1:1000, and endothelial cell marker CD31/PECAM-1 (Cell Signaling, Cat# 77699T) diluted

(11) Structural characterization and immunomodulatory activity of a novel acid polysaccharide isolated from the pulp of Rosa laevigata Michx fruitInternational journal of biological macromoleculesFebruary 15, 2020Zhan Q, Wang Q, Lin R, He P, Lai F, Zhang M, Wu H.

(12) ACT001 reduces the expression of PD-L1 by inhibiting the phosphorylation of STAT3 in glioblastomaTheranosticsJanuary 1, 2020Tong L, Li J, Li Q, Wang X, Medikonda R, Zhao T, Li T, Ma H, Yi L, Liu P, et al.ABclonal (Wuhan, China). Antibodies against CD163 (bs-2527R, dilution for IHC analysis, 1:100), CD206 (bs-4727R, dilution for IHC analysis, 1:100), iNOS (bs-2072R, dilution for IHC analysis, 1:100) and IFNγ (bs-0480R,

(13) Sonodynamic therapy in atherosclerosis by curcumin nanosuspensions: Preparation design, efficacy evaluation, and mechanisms analysisEuropean journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.VJanuary 1, 2020Jiang L, Wang J, Jiang J, Zhang C, Zhao M, Chen Z, Wang N, Hu D, Liu X, Peng H, et al.

(14) A Multi-Functional Silicon Nanoparticle Designed for Enhanced Osteoblast Calcification and Related Combination TherapyMacromolecular bioscienceDecember 1, 2019Shao N, Guan Y, Liu S, Li X, Zhou D, Huang Y.

(15) The effect of exposure to hypoxia on superoxide formation by alveolar macrophages is indirectLife sciencesNovember 1, 2019Žaloudíková M, Vytášek R, Rašková M, Vízek M, Uhlík J, Hampl V.

(16) Exploring the interactions between engineered nanomaterials and immune cells at 3D nano-bio interfaces to discover potent nano-adjuvantsNanomedicine : nanotechnology, biology, and medicineOctober 1, 2019Ma R, Zheng H, Liu Q, Wu D, Li W, Xu S, Cai X, Li R.

(17) Heat injured stromal cells-derived exosomal EGFR enhances prostatic wound healing after thulium laser resection through EMT and NF-κB signalingThe ProstateAugust 1, 2019Shi F, Deng Z, Zhou Z, Jiang B, Jiang CY, Zhao RZ, Sun F, Cui D, Sun MH, Sun Q, et al.

(18) Co-Administration of Curcumin and Artepillin C Induces Development of Brown-Like Adipocytes in Association with Local Norepinephrine Production by Alternatively Activated Macrophages in MiceJournal of nutritional science and vitaminologyJanuary 1, 2019Nishikawa S, Kamiya M, Aoyama H, Yoshimura K, Miyata R, Kumazawa S, Tsuda T.

(19) GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signalingEndocrine-related cancerApril 1, 2018White MA, Tsouko E, Lin C, Rajapakshe K, Spencer JM, Wilkenfeld SR, Vakili SS, Pulliam TL, Awad D, Nikolos F, et al.

(20) Highly Dispersible and Bioavailable Curcumin but not Native Curcumin Induces Brown-Like Adipocyte Formation in MiceMolecular nutrition & food researchMarch 1, 2018Nishikawa S, Kamiya M, Aoyama H, Nomura M, Hyodo T, Ozeki A, Lee H, Takahashi T, Imaizumi A, Tsuda T.

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MRC1 Polyclonal Antibody

MRC1 Polyclonal Antibody from Bioss Inc.

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Bioss Inc.

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MRC1 Polyclonal Antibody from Bioss Inc.

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