VCP (5) Antibody sc-57492 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemVCP (5) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-57492
Antibody TypePrimary Antibodies
NCBI Gene AliasesFTDALS6, TERA, p97, CDC48, 3110001E05, p97/VCP
Quantity200 µg/ml
Clone5
Reactivitymouse, rat, human, porcine
ApplicationsWB, IP, IF, IHC(P)
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
NCBI Full Gene Namevalosin containing protein
TargetVCP
IsotypeIgG2b

Add to Compare List

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfoldingSci AdvMarch 6, 2026Matthias Kracht, Alexander Kröning, Johannes van den Boom, Pinki Gahlot, Sandra Koska, Leo Kiss, Hemmo Meyerglycerol, 1% Triton X-100, and 2 mM β-mercaptoethanol], together with anti-p97 (Santa Cruz Biotechnology, sc-57492; mouse monoclonal, diluted 1:1000) and GammaBind Plus Sepharose (Cytiva). After incubation with constant

(2) Aberrant nuclear pore complex degradation contributes to neurodegeneration in VCP diseaseNeuronMarch 4, 2026Sandeep Kumar Dubey, Divya Chaubey, Chiseko Ikenaga, Wen-Wen Lin, Hugo J. Bellen, Thomas E. LloydRRID:AB_2721935" Rabbit anti-VCP,Cell Signaling Technology,"Cat# 2649, RRID:AB_2214629" Mouse anti-VCP,Santa Cruz,"Cat# sc-57492, RRID:AB_793927" Rabbit anti-TBPH,Nordic Biosite,Cat# ABB-A7SWCZ200 Rabbit anti-TDP-43,Proteintech,"Cat#

(3) Valosin containing protein (VCP/p97) expression in laryngeal squamous cell carcinoma: clinical evaluation and implications for targeted therapyPathology & Oncology ResearchNovember 21, 2025Inga M. C. Seuthe, Hanna C. Hunsicker-Biederbeck, Markus Ruwe, Julius Knierer, Eric Ehrke-Schulz, Eren Erdogan, Sabine Eichhorn, Jonas J.-H. ParkFor detection of VCP/p97, a mouse anti-human monoclonal antibody (Santa Cruz Biotechnology, Cat. No. sc-57492) was applied at a dilution of 1:100. Staining was visualized using the ultraView Universal DAB Detection

(4) Targeting VCP enhances colorectal cancer therapy through STING stabilizationJournal for ImmunoTherapy of CancerNovember 19, 2025Hongdao Zhu, Fujing Ge, Jingyu Dai, Shuyu Yang, Tao Yuan, Churun Zheng, Xin Dong, Ronggui Hu, Tianhua Zhou, Qiaojun He, et al.described.36 The primary antibodies used in this study were: STING (1:200; #A3262; ABclonal), VCP (1:100; # sc-57492; Santa Cruz), PDI (1:200; #45596; Cell Signaling Technology), p-Ser365 STING (1:200; #62912; Cell Signaling Technology

(5) The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagyJournal of Biological ChemistryNovember 1, 2025Wei-Hua Chu, Yu-Shan Lin, Jing Guo, Wann-Neng Jane, Wong-Jing Wang, Yu-Yang Lin, Pei-Han Liu, Po-Yu Huang, Wei-Chung Chiang(Cell signaling Technology, 4211, 1:1000) and mouse anti-V5 tag (Invitrogen R96025, 1:250), and mouse anti-VCP (Santa Cruz sc-57492, 1:1000). The secondary antibodies were Donkey anti-rabbit IgG AlexaFluor 594 (Invitrogen A21207, 1:750),

(6) High VCP/p97 expression associates with low PD-L1 TPS in oropharyngeal squamous cell carcinomaDiscov OncolOctober 20, 2025Inga Marte Charlott Seuthe, Markus Ruwe, Franz Mitze, Steffi Silling, Eric Ehrke-Schulz, Sabine Eichhorn, Jonas Jae-Hyun Parkstaining was conducted using a monoclonal mouse anti-human antibody (Santa Cruz Biotechnology, Cat. No. sc-57492) at a dilution of 1:100. Detection was performed with the ultraView Universal DAB Detection Kit (Roche).

(7) DNA polymerase α/primase extraction from chromatin by VCP/p97 restricts ATR activation during unperturbed DNA replicationNat CommunJuly 1, 2025Sara Rodríguez-Acebes, Rodrigo Martín-Rufo, Alicia Gómez-Moya, Scott B. Churcher, Alejandro Fernández-Llorente, Guillermo de la Vega-Barranco, Alejandra Perona, Pilar Oroz, Elena Martín-Doncel, Luis Ignacio Toledo, et al.antibodies against USP7 (Bethyl A300-033A, 1/1000), VCP (Bethyl A300-589A and Santa Cruz Biotechnologies sc-57492, 1/1000), SUMO2/3 (MBL, M114-3 and University of Iowa, clone 8A2, 1/1000), PCNA (Santa Cruz, sc-56,

(8) C1QL1 inhibits breast cancer through the HSP90α/VCP-ERS/UPR axisExperimental & molecular medicineJune 1, 2025Zhang N, Shao Q, Xiang X, Yan C, Tao D, Li Q, Rong H, Zhao Y, Xiang T, Zeng X.ER-Tracker Red (1:2,000, C1041, Beyotime), anti-HSP90α (1:100, sc-515081, Santa Cruz), anti-VCP (1:100, sc-57492, Santa Cruz), CoraLite 488 (1:200, sc-515081, Proteintech) and CoraLite 594 (1:200, SA00013-4, Proteintech). Western blot Western blot

(9) µMap proximity labeling in living cells reveals stress granule disassembly mechanismsNature Chemical BiologyApril 1, 2025Chenmengxiao (Roderick) Pan, Steve D. Knutson, Sean W. Huth, David W. C. MacMillananti-pan-ubiquitin (Santa Cruz Biotechnology, sc-8017; 1:500), mouse anti-VCP (Santa Cruz Biotechnology, sc-57492; 1:500), rabbit anti-HDAC6 (Cell Signaling Technology, 7558T; 1:200), mouse anti-SQSTM1 (Santa Cruz Biotechnology

(10) Valosin-containing protein p97 extracts capping protein CP110 from the mother centriole to promote ciliogenesisMolecular Biology of the CellMarch 1, 2025Rahit Dewanji, Naava Naslavsky, Steve Caplan(P37, catalog no. 58395; Cell Signaling Technology, Danvers, MA), mouse anti-human VCP/p97 (catalog no. Sc-57492; Santa Cruz Biotechnology, Dallas, TX), rabbit anti-human ARL13B (catalog no. 17711-1-AP; Proteintech),

(11) Localized K63 Ubiquitin Signaling Is Regulated by VCP/p97 During Oxidative StressMolecular & Cellular ProteomicsMarch 1, 2025Austin O. Maduka, Sandhya Manohar, Matthew W. Foster, Gustavo M. Silvaab240562), anti-puromycin (1:7500, MilliporeSigma, MABE343), anti-VCP (1:2500, Santa Cruz Biotechnology, #sc-57492), anti-NPLOC4 (Proteintech, 11638-1-AP), anti-GAPDH (1:10,000, Abcam, ab9485), anti-FLAG (1:2500, MilliporeSigma,

(12) Structure-activity relationship studies and design of a PTPN22 inhibitor with enhanced isozyme selectivity and cellular efficacyEuropean Journal of Medicinal ChemistryFebruary 5, 2025Brenson A. Jassim, Yunpeng Bai, Zihan Qu, Conrad J. Sander, Jianping Lin, Jinmin Miao, Zhong-Yin Zhang(70926) and anti-p-ERK1/2 (T202/Y204) (4370) were purchased from Cell Signaling Technology. Anti-VCP (sc-57492) and anti-ACTIN (sc-8432) antibodies were purchased from Santa Cruz Biotechnology. Supplementary Material

(13) The protein segregase VCP/p97 promotes host antifungal defense via regulation of SYK activationPLOS PathogensOctober 29, 2024Zhugui Shao, Li Wang, Limin Cao, Tian Chen, Xin-Ming Jia, Wanwei Sun, Chengjiang Gao, Hui Xiaoperoxidase-conjugated secondary Abs and anti-β-actin were from Jackson Laboratory; anti-SHP-2 (sc-7384), anti-VCP (sc-57492), anti-UFD1 (sc-377265), anti-SHIP1 (sc-8425), anti-IκBα (sc-371) and Protein A/G PLUS-Agarose (sc-2003)

(14) Molecular profiling of the hippocampus of children with autism spectrum disorderMolecular PsychiatryJuly 1, 2024Lindsay E. Rexrode, Joshua Hartley, Kurt C. Showmaker, Lavanya Challagundla, Michael W. Vandewege, Brigitte E. Martin, Estelle Blair, Ratna Bollavarapu, Rhenius B. Antonyraj, Keauna Hilton, et al.Tech, Rosemont, IL) using VCP for the loading control (mouse anti-VCP, Santa Cruz Biotechnology cat# sc-57492 and rabbit anti-VCP, Abcam Inc. cat# ab111740) according to prior studies [50]. All proteins were visualized

(15) Localized K63 ubiquitin signaling is regulated by VCP/p97 during oxidative stressbioRxivJune 23, 2024Austin O. Maduka, Sandhya Manohar, Matthew W. Foster, Gustavo M. Silvaab240562), anti-puromycin (1:7,500, MilliporeSigma, MABE343), anti-VCP (1:2,500, Santa Cruz Biotechnology, #sc-57492), anti-NPLOC4 (Proteintech, 11638-1-AP), anti-GAPDH (1:10,000, Abcam, ab9485), anti-FLAG (1:2,500, MilliporeSigma,

(16) The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCPeLifeSeptember 15, 2023Körner M, Meyer SR, Marincola G, Kern MJ, Grimm C, Schuelein-Voelk C, Fischer U, Hofmann K, Buchberger A.A300-589A, RRID:AB_495512",WB 1:5000IF 1:300 Antibody,Anti-VCP (mouse monoclonal),Santa Cruz,"Cat# sc-57492, RRID:AB_793927",IF 1:50 Antibody,Anti-FAF1 (rabbit polyclonal),"Max Planck Institute of Biochemistry,

(17) Structural basis of ubiquitin-independent PP1 complex disassembly by p97The EMBO journalJuly 17, 2023van den Boom J, Marini G, Meyer H, Saibil HR.C‐19, Santa Cruz Biotechnology; rabbit polyclonal anti‐Inhibitor‐3 (Kracht et al, 2020) p97 antibody sc‐57492, Santa Cruz; GST antibody G1160, Sigma) or further processed for mass spectrometry analysis as previously

(18) The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseNature communicationsJune 5, 2023Blueggel M, Kroening A, Kracht M, van den Boom J, Dabisch M, Goehring A, Kaschani F, Kaiser M, Bayer P, Meyer H, et al.(1:2000, mouse, clone FK2, Merck 04-263), Anti-VCP/p97 antibody (1:1000, mouse, clone VCP 5, Santa Cruz sc-57492,), Anti-Npl4 (=anti-NPLOC4, 1:1000, rabbit polyclonal, Atlas HPA021560), Anti-penta-His antibody (1:1000,

(19) The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/ArkadiaBMC biologyApril 7, 2023Amhaz S, Boëda B, Chouchène M, Colasse S, Dingli F, Loew D, Henri J, Prunier C, Levy L.(Thermo Fisher Scientific Cat# PA5-61,972, RRID:AB_2649223), anti-VCP (Santa Cruz Biotechnology Cat# sc-57492, RRID:AB_793927), anti-cullin2 (Thermo Fisher Scientific Cat# 51–1800, RRID:AB_2533898), anti-TOPORS

(20) Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson SyndromeGenesMarch 2, 2023Birkhoff JC, Korporaal AL, Brouwer RWW, Nowosad K, Milazzo C, Mouratidou L, van den Hout MCGN, van IJcken WFJ, Huylebroeck D, Conidi A.control, we used Valosin-containing Protein (VCP) and anti-VCP antibody (Santa Cruz, Dallas, TX, USA, sc-57492, mouse). 2.3. RNA Extraction and RT-qPCR Analysis Total RNA was extracted from ESCs using TRI Reagent

Be the First to Write a Review!

VCP (5) Antibody

VCP (5) Antibody from Santa Cruz Biotechnology, Inc.

Description

Santa Cruz Biotechnology, Inc.

Citations (36)

Reviews

VCP (5) Antibody from Santa Cruz Biotechnology, Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map