HSP 40-4 (KA2A5.6) Antibody sc-59554 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHSP 40-4 (KA2A5.6) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-59554
Antibody TypePrimary Antibodies
NCBI Gene AliasesHSDJ, Hsj2, DjA1, DJ-2, HDJ2, HSPF4, Nedd7, hDJ-2, HSJ-2, HSJ2, NEDD7
CloneKA2A5.6
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), FCM
Reactivitymouse, rat, human, porcine
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene NameDnaJ heat shock protein family (Hsp40) member A1
TargetHSP 40-4
IsotypeIgG1

Questions and Answers

Can this antibody be used to study the role of HSP40 in CFTR trafficking?

Yes, the HSP 40-4 (KA2A5.6) antibody has been utilized in studies investigating the role of HSP40 in CFTR trafficking. For instance, it was shown that HSP40, along with HSP70, is involved in the degradation of CFTR, highlighting its significance in the regulation of CFTR levels and function ().

Is this antibody effective for immunoprecipitation assays?

The HSP 40-4 antibody has been successfully used in immunoprecipitation assays, as demonstrated in various studies. For example, it was employed to co-immunoprecipitate HSP40 in experiments assessing its interaction with other proteins involved in CFTR regulation ().

What species can this antibody be used with?

The HSP 40-4 antibody is reactive with multiple species, including porcine, human, mouse, and rat, making it versatile for studies across different model organisms.

Are there any specific applications where this antibody has been cited?

The HSP 40-4 antibody has been cited in applications such as Western blotting, flow cytometry, immunofluorescence, and immunohistochemistry, indicating its broad utility in various experimental contexts (, ).

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Inhibiting Isoprenylation Suppresses FcεRI-Mediated Mast Cell Function and Allergic InflammationThe Journal of ImmunologyAugust 15, 2023Jordan M. Dailey, Sydney A. Kee, Anuj Tharakan, Aslamuzzaman Kazi, Jason R. Burchett, Elizabeth Motunrayo Kolawole, William Boyd Boyd Ballance, Aditya Kotha, Quang T. Le, Lawrence B. Schwartz, et al.albumin (DNP-HSA) were from Sigma-Aldrich (St. Louis, MO). Antibodies against N-Ras (sc-31), HDJ2 (sc-59554), pggt1b (sc-376854), FTα (sc-23906) and Rap1a (sc-1482) were obtained from Santa-Cruz (Dallas, TX).

(2) Dysregulation and oncogenic activities of ubiquitin specific peptidase 2a in the pathogenesis of hepatocellular carcinomaAmerican journal of cancer researchJanuary 1, 2023Zhang X, Nadolny C, Chen Q, Ali W, Hashmi SF, Deng R.

(3) Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in miceMolecular neurodegenerationAugust 20, 2022Cuddy LK, Alia AO, Salvo MA, Chandra S, Grammatopoulos TN, Justman CJ, Lansbury PT Jr, Mazzulli JR, Vassar R.

(4) DjA1 maintains Golgi integrity via interaction with GRASP65Molecular biology of the cellFebruary 15, 2019Li J, Tang D, Ireland SC, Wang Y.monoclonal antibodies against β-actin (AC-15, SigmaAldrich), clathrin (X22, Affinity Bioreagent), DjA1 (sc-59554, Santa Cruz), GM130 (610823, BD Biosciences), and histidine (His) tag (66005, Proteintech); and polyclonal

(5) Hsp70 and DNAJA2 limit CFTR levels through degradationPloS oneJanuary 1, 2019Kim Chiaw P, Hantouche C, Wong MJH, Matthes E, Robert R, Hanrahan JW, Shrier A, Young JC.from StressMarq. Anti-CHIP (C9243), anti-Flag M2 (F1804) were from Sigma-Aldrich. Anti-DJA1, KA2A5.6 (sc-59554), anti-myc (SC-40) and anti-RhoB (SC-180) were from Santa Cruz Biotechnology. Anti-HA.11 clone 16B12

(6) Combination of Correctors Rescues CFTR Transmembrane-Domain Mutants by Mitigating their Interactions with ProteostasisCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2017Lopes-Pacheco M, Boinot C, Sabirzhanova I, Rapino D, Cebotaru L.

(7) DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathwayNature cell biologyNovember 1, 2016Parrales A, Ranjan A, Iyer SV, Padhye S, Weir SJ, Roy A, Iwakuma T.

(8) Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosisScientific reportsJanuary 1, 0001"Chou CW, Lin CH, Hsiao TH, Lo CC, Hsieh CY, Huang CC, Sher YP."Cell Signaling Technology), α-tubulin (NB100-690; Novus Biologicals), GAPDH (10494-1-AP; Proteintech), HSP-40 (sc-59554; Santa Cruz Biotechnology), CHIP (sc-133066; Santa Cruz Biotechnology), and vinculin (GTX109749; GeneTex).

(9) The CFTR-Associated Ligand Arrests the Trafficking of the Mutant ΔF508 CFTR Channel in the ER Contributing to Cystic Fibrosis"Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology"January 1, 0001"Bergbower E, Boinot C, Sabirzhanova I, Guggino W, Cebotaru L."(Millipore); mouse monoclonal anti-GFP (Roche); HA-probe (sc-7392), VCP (sc-133125), HSP70 (sc-66048), HSP40 (sc-59554), NHERF1, and Ezrin (sc-58758) were purchased from Santa Cruz Biotechnology; rabbit monoclonal anti-PIST

(10) Distinct roles of molecular chaperones HSP90α and HSP90β in the biogenesis of KCNQ4 channelsPloS oneJanuary 1, 0001"Gao Y, Yechikov S, Vazquez AE, Chen D, Nie L."PA, USA), and those from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA, USA), including anti-DjA1 (sc-59554), anti-DjA2 (sc-107520), anti-HSC70 (sc-1059), anti- HSP70 (sc-1060), and anti-HSP90 β (sc-1057). All

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HSP 40-4 (KA2A5.6) Antibody

HSP 40-4 (KA2A5.6) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HSP 40-4 (KA2A5.6) Antibody from Santa Cruz Biotechnology, Inc.

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