Fig 1: MYCL Promotes Development of NE Lesions in the Alveolar Space(A) Part of a bronchial tree in an RP mouse (n = 13 mice) showing several bronchial lesions.(B) Part of a bronchial tree in an RPM mouse (n = 17 mice) showing multiple bronchial and alveolar lesions.(C) Alveolar lesion showing pseudo-glandular structures.(D) Ki67 staining showing proliferating cells within alveolar lesion and within the adjacent intrapulmonary metastasis lesion.(E) Magnification of the area within (D).(F) ASCL1 staining of alveolar lesion.(G–I) CDH1 (G), CGRP (H), and NFIB (I) staining of three alveolar lesions in close proximity to intrapulmonary metastasis lesions (sequential sections).Scale bar for (A), (B), (D), and (G)–(I), 500 µm. Scale bar for (C), 20 µm. Scale bar for (E) and (F), 50 µm. See also Figure S1.