The TPMT antibody (clone AT2E7) from MyBioSource.com is a Mouse Monoclonal antibody to TPMT. This antibody recognizes Human antigen. The TPMT antibody (clone AT2E7) has been shown to work in the following applications: ELISA, and Western Blot.
Description
TPMT(Thiopurine S-methyltransferase) is a very important enzyme for the metabolizm of thiopurine compounds. TPMT pharmacogenetics has been studied extensively because of its clinical significance. Many patients got benefited from the knowledge of TPMT genotype-phenotype correlation. Also, TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity