The Anti-PKB alpha antibody (monoclonal) from MyBioSource.com is a Mouse Monoclonal antibody to AKT1, and RAC. This antibody recognizes Human, Mouse, Rat, and Chicken/Bird antigen. The Anti-PKB alpha antibody (monoclonal) has been shown to work in the following applications: Western Blot.
Description
Description: Mouse IgG monoclonal antibody for PKB alpha, v-akt murine thymoma viral oncogene homolog 1 (AKT1) detection. Tested with WB in Human, mouse, rat, chicken. No cross reactivity with other proteins. Uniprot ID: P31749
Background: PKB alpha also knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo