MDM2 (D-7) Antibody sc-13161 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMDM2 (D-7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13161
NCBI Gene AliasesLSKB, 1700007J15Rik, Mdm-2, HDMX, ACTFS, hdm2
Antibody TypePrimary Antibodies
CloneD-7
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), ELISA
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
Hostmouse
NCBI Full Gene NameMDM2 proto-oncogene, transformed mouse 3T3 cell double minute 2
TargetMDM2
IsotypeIgG2b

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) CircAFF3 modulation of p53–ID2 signaling in the retinal pigment epithelium links inflammation with cell death in dry age-related macular degenerationFrontiers in Cell and Developmental BiologyMarch 25, 2026Yeongseo Ryu, Dahee Jeong, Jeong Hun Kim, Young-Kook Kim(Cell Signaling Technology, 9541s), BAX (Cell Signaling Technology, 2772s), p53 (Santa Cruz, sc-126), MDM2 (Santa Cruz, sc-13161), Histone H3 (Cell Signaling Technology, 4499s), Lamin B1 (Abcam, ab16048), and GAPDH (Santa Cruz, sc-32233).

(2) Antisense-mediated splicing correction as a therapeutic approach for p53 K120R mutationBMB ReportsNovember 30, 2024Doyeong Kim, Sang-Min Park, Seo-Young Lee, Jinchul Kim, Han-Byul Jung, Young Sook Kim, Sun-Ku ChungTechnology; Cat#12D1), PUMA (Santa Cruz Biotechnology; Cat# sc-374223), MDM2 (Santa Cruz Biotechnology; Cat# sc-13161), and β-actin (Santa Cruz Biotechnology; Cat# sc-47778). After incubation with goat anti-rabbit (Cat#

(3) DBC1 maintains skeletal muscle integrity by enhancing myogenesis and preventing myofibre wastingJournal of Cachexia, Sarcopenia and MuscleFebruary 1, 2024Na Liang, Jia He, Jiaqi Yan, Xueying Han, Xiaoqian Zhang, Yamei Niu, Wuga Sha, Jun Lianti‐Murf1 (1:500, Santa Cruz, sc‐398608), anti‐LC3 (1:500, ABclonal, A19665), anti‐MDM2 (1:500, Santa Cruz, sc‐13161), anti‐ubiquitin (1:500, Santa Cruz, sc‐8017), anti‐β‐tubulin (1:5000, CMCTAG, AT0003) and anti‐GAPDH

(4) Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia EffectFrontiers in immunologyJanuary 1, 2022Huang Y, Zou Y, Jiao Y, Shi P, Nie X, Huang W, Xiong C, Choi M, Huang C, Macintyre AN, et al.anti-Mcl-1 antibody (clone Y37, ab32087) were purchased from Abcam. Anti-Mdm2 antibody (clone D-7, sc-13161) was purchased from Santa Cruz Biotechnology Inc. (Dallas. TX). Statistics Data were analyzed using

(5) Systems-Level Mapping of Cancer Testis Antigen 1b/a to Sarcoma Pathways Identifies Activated Ran Binding-2 E3 SUMO-Protein Ligase and Transducin-Like Enhancer Protein 1Frontiers in geneticsJanuary 1, 2022Papanikolaou NA, Hytiroglou P, Pantelidou P, Papavassiliou AG, Old LL.(sc-53868), Ranbp2 (ABCAM, PAB 2938TRS), TLE1 (ABCAM, PAb, 15587syn), MDM2 (Santa-Cruz Biotechnology, D-7, sc-13161). Tissue sections were deparaffinized in xylene and graded alcohols. The stains were performed in an

(6) Nuclear expression of MDM2 in hibernoma: a potential diagnostic pitfallVirchows Archiv : an international journal of pathologyMarch 1, 2021Tsuda Y, Matsuyama A, Makihara K, Higaki K, Motoi T, Okuma T, Hisaoka M.

(7) USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancyScientific reportsNovember 30, 2020Wang SA, Young MJ, Jeng WY, Liu CY, Hung JJ.anti-securin (Cat# ab-79546, Abcam, 1:1000), anti-E2F4 (Cat# ab-150360, Abcam, 1:1000), anti-mdm2 (Cat# sc-13161, Santa Cruz, 1:1000), anti-PCAF (Cat# 109666, Genetex, 1:1000), anti-BRD3 (Cat# 115058, Genetex, 1:1000)

(8) Deferasirox-Dependent Iron Chelation Enhances Mitochondrial Dysfunction and Restores p53 Signaling by Stabilization of p53 Family Members in Leukemic CellsInternational journal of molecular sciencesOctober 16, 2020Calabrese C, Panuzzo C, Stanga S, Andreani G, Ravera S, Maglione A, Pironi L, Petiti J, Shahzad Ali MS, Scaravaglio P, et al.Cell Signaling Technology, Danvers, MA, USA, p21 sc-6246, Santa Cruz Biotechnology, Dallas, TX, USA, MDM2, sc-13161, Santa Cruz Biotechnology, Dallas, TX, USA, Cleaved Caspase 3, #9664, Cell Signaling Technology, Danvers,

(9) Cisplatin in Combination with MDM2 Inhibition Downregulates Rad51 Recombinase in a Bimodal Manner to Inhibit Homologous Recombination and Augment Tumor Cell KillMolecular pharmacologyApril 1, 2020Xie X, He G, Siddik ZH.Protein A beads (sc-2001) and antibodies for p53 (DO-7: sc-47698; FL-393: sc-6243), p21 (sc-6246), MDM2 (sc-13161), and b-actin (sc-47778) were purchased from Santa Cruz (Dallas, TX). Anti-MDM4 (A700-000) was purchased

(10) IU1 suppresses proliferation of cervical cancer cells through MDM2 degradationInternational journal of biological sciencesJanuary 1, 2020Xu L, Wang J, Yuan X, Yang S, Xu X, Li K, He Y, Wei L, Zhang J, Tian Y.(Abcam, ab128025, 1:1000), p62 (Protein Tech, 18420-1-AP, 1:1000), MDM2 (Santa Cruz Biotechnology, sc-13161, 1:1000), ubiquitin (Abcam, ab7780, 1:1000), USP14 (Abcam, ab192618, 1:1000), HA-tag (Proteintech Group,

(11) Stress-specific aggregation of proteins in the amyloid bodiesFEBS lettersNovember 1, 2019Marijan D, Tse R, Elliott K, Chandhok S, Luo M, Lacroix E, Audas TE.

(12) Oxidative stress-mediated TXNIP loss causes RPE dysfunctionExperimental & molecular medicineOctober 15, 2019Ji Cho M, Yoon SJ, Kim W, Park J, Lee J, Park JG, Cho YL, Hun Kim J, Jang H, Park YJ, et al.anti-β-actin (AbC-2004, 1:5000, AbClon, South Korea), anti-LC3B (L7543, 1:5000, Sigma), anti-MDM2 (sc-13161, 1:1000, Santa Cruz, USA), anti-HIF-1a (NB100-105, 1: 1000, Novus Biologicals, USA), anti-p53 (sc-126,

(13) MicroRNA-26a targets the mdm2/p53 loop directly in response to liver regenerationInternational journal of molecular medicineOctober 1, 2019Zhou J, Li Z, Huang Y, Ju W, Wang D, Zhu X, He X.temperature for 1 h. Antibodies (all, 1:1,000) included anti‑p53 (cat. no. sc‑71817), anti‑mdm2 (cat. no. sc‑13161), anti‑p21 (cat. no. sc‑53870), anti‑p27 (cat. no. sc‑53906; all, Santa Cruz Biotechnology, Inc., Dallas,

(14) Isobavachalcone exerts anti‑proliferative and pro‑apoptotic effects on human liver cancer cells by targeting the ERKs/RSK2 signaling pathwayOncology reportsJune 1, 2019Li B, Xu N, Wan Z, Ma L, Li H, Cai W, Chen X, Huang Z, He Z.3355-3366, 2019 MA, USA); mouse monoclonal antibodies against mouse double minute 2 homolog (MDM2; cat. no. sc‑13161; 1:500), RSK2 (cat. no. sc‑9968; 10 µl) and β‑actin (cat. no. sc‑8432; 1:1,000) purchased from Santa Cruz Biotechnology, Inc

(15) p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cellsThe Journal of biological chemistryMarch 8, 2019Rangel LP, Ferretti GDS, Costa CL, Andrade SMMV, Carvalho RS, Costa DCF, Silva JL.

(16) p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutantCancer & metabolismJanuary 1, 2018Humpton TJ, Hock AK, Maddocks ODK, Vousden KH.Infrared Scanner and LiCor Image Studio Software. Primary antibodies MDM2 (SMP-14) (sc-965), MDM2 (D-7)(sc-13161), CREB-2 (B-3)(sc-390063), p53 (DO-1) (sc-126), PSPH (H-11)(sc-365183), PSAT1 (L-24)(sc-133929), p53

(17) Functional Activation of Mutant p53 by Platinum Analogues in Cisplatin-Resistant Cells Is Dependent on PhosphorylationMolecular cancer research : MCRMarch 1, 2017Xie X, He G, Siddik ZH.Protein A beads (sc-2001) and antibodies for p53 (DO-7: sc-47698; FL-393: sc-6243), p21 (sc-6246), MDM2 (sc-13161), MDM4 (sc-374147) and β-actin (sc-47778) were purchased from Santa Cruz. Phospho-specific antibodies

(18) Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53OncogeneSeptember 8, 2016Xie X, Lozano G, Siddik ZH.Protein A beads (sc-2001) and antibodies for p53 (sc-126, sc-47698, sc-6243), p21 (sc-6246), MDM2 (sc-13161), MDM4 (sc-374147) and β-actin (sc-47778) were purchased from Santa Cruz, MTT (19265) from Affymetrix,

(19) Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanismseLifeMay 27, 2014Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, et al.Covance (Dedham, MA) MMS134R; RNAPII S2P (H5): Covance MMS129R; p53: Calbiochem OP43; MDM2: Santa Cruz sc-13161 (D-7); normal mouse IgG: Santa Cruz sc-2025. Primers used for ChIP Location of amplicon center relative

(20) Liberation of functional p53 by proteasome inhibition in human papilloma virus-positive head and neck squamous cell carcinoma cells promotes apoptosis and cell cycle arrestCell cycle (Georgetown, Tex.)March 15, 2013Li C, Johnson DE.

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MDM2 (D-7) Antibody

MDM2 (D-7) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MDM2 (D-7) Antibody from Santa Cruz Biotechnology, Inc.

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