XPE/DDB2 Antibody AF3297 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemXPE/DDB2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF3297
NCBI Gene AliasesDDBB, UV-DDB2, XPE
ApplicationsWestern Blot,Immunocytochemistry
Conjugate/TagUnconjugated
IsotypeIgG
Quantity100 ug (also 25 ug)
ReactivityHuman
HostGoat
TargetXPE/DDB2
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
NCBI Full Gene Namedamage specific DNA binding protein 2
ImmunogenE. coli-derived recombinant human XPE/DDB2, Met1-Lys427, Accession # Q92466
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ClonalityPolyclonal

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human XPE/DDB2 in Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Structural basis of cyclobutane pyrimidine dimer recognition by UV-DDB in the nucleosomeNature CommunicationsNovember 11, 2025Syota Matsumoto, Yoshimasa Takizawa, Mitsuo Ogasawara, Kana Hashimoto, Lumi Negishi, Wenjie Xu, Haruna Tachibana, Junpei Yamamoto, Shigenori Iwai, Kaoru Sugasawa, et al.following primary antibodies were used in this study with the indicated dilutions: Anti-DDB2 antibody AF3297 (R&D Systems, catalog# AF3297; 1:500 for immunostaining, 1:2000 for immunoblotting), anti-beta-actin

(2) Fluorescence-microscopy-based assay assessing regulatory mechanisms of global genome nucleotide excision repair in cultured cellsSTAR protocolsSeptember 15, 2023Kusakabe M, Sugasawa K.anti-XPC (D-10),Santa Cruz Biotechnology,Cat#: sc-74410; RRID: AB_1131407 Goat polyclonal anti-DDB2,R&D Systems,Cat#: AF3297; RRID: AB_2088829 Mouse monoclonal anti-α-tubulin (B-5-1-2),Merck,Cat#: T5168; RRID: AB_477579 Mouse

(3) XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repairNature communicationsAugust 13, 2022Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, et al.

(4) Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC proteiniScienceApril 15, 2022Kusakabe M, Kakumu E, Kurihara F, Tsuchida K, Maeda T, Tada H, Kusao K, Kato A, Yasuda T, Matsuda T, et al.anti-XPC (D-10),Santa Cruz Biotechnology,Cat#: sc-74410; RRID: AB_1131407 Goat polyclonal anti-DDB2,R&D Systems,Cat#: AF3297; RRID: AB_2088829 Mouse monoclonal anti-α-tubulin (B-5-1-2),Merck,Cat#: T5168; RRID: AB_477579 Mouse

(5) Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolismScientific reportsMarch 28, 2019Lai TC, Hu MC.

(6) Human CRL4^DDB2 ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56Ac through recruitment of histone chaperon CAF-1OncotargetNovember 28, 2017Zhu Q, Wei S, Sharma N, Wani G, He J, Wani AA.(A300-739A), p300 (A300-358A) and DDB1 (A300-462A) antibodies were from Bethyl Laboratories. Anti-DDB2 (AF3297) was purchased from R&D Systems (Minneapolis, MN 55413); CAF-1 p60 (Ab8133), p150 (Ab7655) and CAF-1

(7) DDB2 increases radioresistance of NSCLC cells by enhancing DNA damage responsesTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineOctober 1, 2016Zou N, Xie G, Cui T, Srivastava AK, Qu M, Yang L, Wei S, Zheng Y, Wang QE.immunodetected with appropriate antibodies, e.g., goat anti-DDB2 (R&D Systems, Minneapolis, MN, USA. Cat. No. AF3297, 1:2000), rabbit anti-cleaved PARP (Cell Signaling Technology, Danvers, MA, USA, Cat. No. 5625, 1:1000),

(8) Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repairScientific reportsJanuary 1, 0001"Sakai W, Yuasa-Sunagawa M, Kusakabe M, Kishimoto A, Matsui T, Kaneko Y, Akagi JI, Huyghe N, Ikura M, Ikura T, et al."antibodies were purchased from manufacturers: XPC (NB100-477, Novus Biologicals, Centennial, CO, USA), DDB2 (AF3297, R&D Systems, Minneapolis, MN, USA), CUL4A (14851-1-AP, Proteintech, Rosemont, IL, USA), multi-ubiquitin

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Human XPE/DDB2 Antibody

XPE/DDB2 Antibody

XPE/DDB2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (8)

Reviews

XPE/DDB2 Antibody from R&D Systems, a Bio-Techne Brand

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