Sortilin Antibody MAB3154 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSortilin Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $449.00Supplier Page View Company Product Page
Catalog NumberMAB3154
NCBI Gene AliasesNT3, Gp95, LDLCQ6, NTR3
ApplicationsWestern Blot,Simple Western
Quantity100 ug (also 25 ug)
TargetSortilin
IsotypeIgG1
HostMouse
Conjugate/TagUnconjugated
ReactivityHuman,Mouse,Rat
Clone334708
NCBI Full Gene Namesortilin 1
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant human Sortilin, Ser78-Asn755, Accession # Q99523
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
ValidationKnockout Validated
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human, mouse, and rat Sortilin in Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Oxidative Stress Suppresses Trk Signaling While Stimulating JNK ‐Mediated Endocytosis and Cleavage of p75 NTR : A Targetable Pathway for Neuroprotection in a Parkinson's Disease ModelJournal of NeurochemistryFebruary 1, 2025Poshan V. Pokharel, Aaron M. Newchurch, Sunny C. Overby, Cassidy A. Spease, Isaac T. Perkins, Lorelei G. Darzi, Nabin Ghimire, Ahmed Lawan, Bradley R. Kraemerp75NTR-ICD (a generous gift from Dr. Bruce Carter, Vanderbilt University), sortilin (R&D Systems, Cat No. MAB3154), TrkA (Cell Signaling Technology, Danvers, MA, USA, Cat No. 2505), TrkB (Cell Signaling Technology,

(2) LM11a-31 Inhibits p75 Neurotrophin Receptor (p75 (NTR) ) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson's DiseasebioRxiv : the preprint server for biologySeptember 13, 2024Pokharel PV, Newchurch AM, Overby SC, Spease CA, Darzi LG, Kraemer BR.

(3) Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in AdipocytesInternational journal of molecular sciencesSeptember 20, 2023Lui A, Patel RS, Krause-Hauch M, Sparks RP, Patel NA.Membranes were probed with Sortilin N- terminal antibody to visualize both splice variants (R&D Systems MAB3154; RRID: AB_2192601, Minneapolis, MN, USA), Sortilin C- terminal antibody to visualize full length sortilin

(4) A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)Molecular & cellular proteomics : MCPFebruary 1, 2017Van Puyenbroeck V, Claeys E, Schols D, Bell TW, Vermeire K.

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Sortilin Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Sortilin Antibody from R&D Systems, a Bio-Techne Brand

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