beta-1 Adrenergic Receptor Antibody PA1-049 from Thermo Fisher Scientific

Product Specs
Itembeta-1 Adrenergic Receptor Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-049
Quantity100 µL
ApplicationsImmunocytochemistry, Immunohistochemistry, Western Blot
ReactivityHuman, Mouse, Non-human primate, Rat
Targetbeta-1 Adrenergic Receptor
HostRabbit
Formatwhole serum with 0.05% sodium azide
ClonalityPolyclonal
ImmunogenSynthetic peptide corresponding to residues H(394) G D R P R A S G C L A R A G(408) of mouse B1AR
IsotypeIgG
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
Conjugate/TagUnconjugated
NCBI Full Gene Nameadrenoceptor beta 1, adrenergic receptor, beta 1
NCBI Gene AliasesRATB1AR, FNSS2, ADRB1R, RHR, Adrb-1, beta-AR, B1AR, BETA1AR
Antibody TypePrimary
Storage-20°C, Avoid Freeze/Thaw Cycles

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Waltham, MA 02451

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Website: www.thermofisher.com

(1) Heterogeneity of estrogen and β-adrenergic receptors in female human coronary artery endothelial cellsInt J Cardiol Heart VascMay 15, 2026Basant Elsaid, Irakli Kopaliani, Ansam Seif, Stephan Speier, Andreas Deussenantibody (1:100, Abcam, ab3575), GPR30 rabbit polyclonal antibody (1:100, Thermo Fisher Scientific, PA1-049), β1-AR rabbit polyclonal antibody (1:100, Thermo Fisher Scientific, PA1-049), β2-AR rabbit polyclonal

(2) Generation of human pineal gland organoids with melatonin production for disease modelingCell stem cellJanuary 8, 2026Kiral FR, Yang WS, Iyilikci O, Lu X, Kim J, Choe MS, Lo C, Zhong M, Kim KY, Jiang YH, et al.LS-C691646), rabbit anti-ADRA1B (1:500, ThermoFisher, PA5–77285), rabbit anti-ADRB1 (1:500, ThermoFisher, PA1–049), rabbit anti-phospho-AANAT (1:200, Invitrogen, PA1–761), goat anti-14–3-3 zeta (1:500, R&D Systems,

(3) Adaptive and Pathological Changes of the Cardiac Muscle in a Mouse Model of Renocardiac Syndrome: The Role of Nestin-Positive CellsInt J Mol SciAugust 21, 2025Polina A. Abramicheva, Ilya A. Sokolov, Arina A. Druzhinina, Daria M. Potashnikova, Nadezda V. Andrianova, Dmitry S. Semenovich, Vasily N. Manskikh, Ljubava D. Zorova, Elmira I. Yakupova, Ivan M. Vikhlyantsev, et al.rabbit, CX40-S, Alpha Diagnostic International, San Antonio, TX, USA), β1-AR (1:100, rabbit, β1-AR PA1-049, Invitrogen, Carlsbad, CA, USA), GATA4 (1:400, rabbit, PA1-102, Invitrogen, Carlsbad, CA, USA), or vWF

(4) Chronic Partial Sleep Deprivation Increased the Incidence of Atrial Fibrillation by Promoting Pulmonary Vein and Atrial Arrhythmogenesis in a Rodent ModelInternational journal of molecular sciencesJuly 11, 2024Liu SH, Lin FJ, Kao YH, Chen PH, Lin YK, Lu YY, Chen YC, Chen YJ.membranes. All blots were probed with primary antibodies against a beta-1 adrenergic receptor (β1-AR, #PA1-049, Thermo Fisher Scientific, Waltham, MA, USA), G protein-coupled receptor kinase 2 (GRK2, #SC-562, Santa Cruz Biotechnology

(5) Cutaneous Calcium/Calmodulin-Dependent Protein Kinase II-γ-Positive Sympathetic Nerves Secreting Norepinephrine Dictate PsoriasisAdvanced science (Weinheim, Baden-Wurttemberg, Germany)June 1, 2024Yu Y, Chen W, Li B, Li Z, Wang Y, Mao Y, Fan W, Bai Y, Hu H, Zhen Q, et al.

(6) CP-25 inhibits the hyperactivation of rheumatic synoviocytes by suppressing the switch in G(αs)-G(αi) coupling to the β(2)-adrenergic receptorCell communication and signaling : CCSNovember 30, 2023Ge M, Wu L, He F, Tai Y, Fang R, Han D, Guo P, Liu H, Hu Y, Xu S, et al.at 37 °C for 2 h, followed by incubation with a primary antibody against β1AR (1:1000, Catalogue # PA1-049, Thermo Fisher Scientific, Waltham, MA, USA), β2AR (1:600, Catalogue # sc-570, Santa Cruz Biotechnology,

(7) CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factorJournal of molecular and cellular cardiologyFebruary 1, 2023Haugsten Hansen M, Sadredini M, Hasic A, Anderson ME, Sjaastad I, Korseberg Stokke M.

(8) Propranolol Modulates Cerebellar Circuit Activity and Reduces TremorCellsDecember 1, 2022Zhou J, Van der Heijden ME, Salazar Leon LE, Lin T, Miterko LN, Kizek DJ, Perez RM, Pavešković M, Brown AM, Sillitoe RV.and allowed to dry. Rabbit polyclonal anti-β1 receptor (1:200; Invitrogen, Waltham, MA, USA; catalog #PA1-049, RRID:AB_2289444) and anti-β2 receptor (1:200; abcam; Cambridge, UK; catalog#ab182136, RRID:AB_2747383)

(9) Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomainsJCI insightNovember 22, 2022Ren L, Thai PN, Gopireddy RR, Timofeyev V, Ledford HA, Woltz RL, Park S, Puglisi JL, Moreno CM, Santana LF, et al.antibodies including anti-HCN4 (1:500 dilution, APC-052, Alomone Labs), anti–β1-AR (1:1,000 dilution, PA1-049, Thermo Fisher Scientific), anti–β2-AR (1:1,000, PA5-27083, Thermo Fisher Scientific), anti–GRK-5 (1:1,000

(10) Positive Effects of a Mediterranean Diet Supplemented with Almonds on Female Adipose Tissue Biology in Severe ObesityNutrientsJune 24, 2022Osorio-Conles Ó, Olbeyra R, Moizé V, Ibarzabal A, Giró O, Viaplana J, Jiménez A, Vidal J, de Hollanda A.mouse, 1:200), UCP3 (ab180643, Abcam, rabbit, 1:100), PPARG (ab45036, Abcam, rabbit, 1:200) and ADRB1 (PA1-049, Thermo-Fisher, rabbit, 1:100). Tissue sections were rehydrated and subjected to heat-mediated antigen

(11) Basolateral amygdala activation enhances object recognition memory by inhibiting anterior insular cortex activityProceedings of the National Academy of Sciences of the United States of AmericaMay 31, 2022Chen YF, Song Q, Colucci P, Maltese F, Siller-Pérez C, Prins K, McGaugh JL, Hermans EJ, Campolongo P, Nadif Kasri N, et al.(Bio-Rad, 170–4156), and probed with antibodies against the β1-adrenoceptor (Rabbit, 1:1,000, Invitrogen PA1-049) and β2-adrenoceptor (Mouse, 1:100, Santa Cruz, sc-271322) and glyceraldehyde 3-phosphate dehydrogenase

(12) Protein Restriction in the Peri-Pubertal Period Induces Autonomic Dysfunction and Cardiac and Vascular Structural Changes in Adult RatsFrontiers in PhysiologyApril 28, 2022Anna Rebeka Oliveira Ferreira et al.Antibody,Manufacturer and Catalog,Source,Dilution Anti-B1 AR,"Thermo Fisher Scientific, MA United States (PA1-049)",Mouse monoclonal,1:1000 Anti α1 AR,"Thermo Fisher Scientific, MA United States (PA1-047)",Mouse monoclonal,1:1000 Anti

(13) Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressureNature communicationsJune 17, 2021Funato Y, Yamazaki D, Okuzaki D, Yamamoto N, Miki H.analyses), anti-AGT antibody (28101; IBL, 1/100 dilution for immunoblotting analyses), anti-β1-AR antibody (PA1049; Invitrogen, 1/1000 dilution for immunoblotting analyses and 1/100 dilution for immunofluorescence analyses),

(14) Exercise Training Stabilizes RyR2-Dependent Ca²⁺ Release in Post-infarction Heart FailureFrontiers in cardiovascular medicineJanuary 1, 2020Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, et al.no. MA3-919 (Thermo Fisher Scientific Inc., Rockford, IL, USA), beta1 adrenergic receptor antibody (PA1-049, Thermo Fisher), and monoclonal antivinculin antibody produced in mouse (V9131, Sigma-Aldrich). Secondary

(15) Regulation of cardiac myocyte cohesion and gap junctions via desmosomal adhesionActa physiologica (Oxford, England)June 1, 2019Schinner C, Erber BM, Yeruva S, Waschke J.

(16) Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2Frontiers in pharmacologyJanuary 1, 2019Cannavo A, Marzano F, Elia A, Liccardo D, Bencivenga L, Gambino G, Perna C, Rapacciuolo A, Cittadini A, Ferrara N, et al.total IRS1 (tIRS1, sc-515017, Santa Cruz Biotechnology, 1:1,000); and h) β-1 adrenergic receptor (β1AR, PA1-049, Invitrogen, 1:1,000) were assessed. Cyclic Adenosine 3′,5′-Monophosphate (cAMP) Assay cAMP levels

(17) FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosisNature cell biologySeptember 1, 2018Chan Wah Hak L, Khan S, Di Meglio I, Law AL, Lucken-Ardjomande Häsler S, Quintaneiro LM, Ferreira APA, Krause M, McMahon HT, Boucrot E.anti-β1 adrenergic receptor (rabbit polyclonal, AbCam ab3442 for immunostaining or Thermo Scientific PA1-049 for western-blotting), anti-Lamellipodin (Lpd) (mouse monoclonal clone H-5, Santa Cruz sc-390050 and

(18) Atrial arrhythmias and autonomic dysfunction in rats exposed to chronic intermittent hypoxiaAmerican journal of physiology. Heart and circulatory physiologyJune 1, 2018Bober SL, Ciriello J, Jones DL.overnight with polyclonal primary antibodies at 4°C, including rabbit anti-␤1-adrenergic receptor (1:2,000, PA1-049; ThermoFisher Scientific, Rockford, IL), rabbit anti-M2 muscarinic receptor (1:800, AB5166, Millipore,

(19) Upregulation of β1-adrenoceptors is involved in the formation of gastric dysmotility in the 6-hydroxydopamine rat model of Parkinson's diseaseTranslational research : the journal of laboratory and clinical medicineJuly 1, 2014Song J, Zheng L, Zhang X, Feng X, Fan R, Sun L, Hong F, Zhang Y, Zhu J.

(20) Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathwaysAge (Dordrecht, Netherlands)October 1, 2013Rudolf R, Bogomolovas J, Strack S, Choi KR, Khan MM, Wagner A, Brohm K, Hanashima A, Gasch A, Labeit D, et al.BD Bioscience and Sigma-Aldrich, respectively. Polyclonal antibody against β1-adrenergic receptor (PA1-049) was from Affinity Bioreagents. Secondary anti-mouse and anti-rabbit antibodies coupled to HRP were

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beta-1 Adrenergic Receptor Antibody from Thermo Fisher Scientific

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beta-1 Adrenergic Receptor Antibody from Thermo Fisher Scientific

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