PICH (D4G8) Rabbit mAb 8886S from Cell Signaling Technology

Product Specs
ItemPICH (D4G8) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8886S
NCBI Gene AliasesPICH, RAD26L
Quantity100 µl
ApplicationsW
ReactivityH, Mk
TargetPICH
HostRabbit
ClonalityMonoclonal
NCBI Full Gene NameERCC excision repair 6 like, spindle assembly checkpoint helicase
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD4G8
Molecular Weight175

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) ANKLE1 processes chromatin bridges by cleaving mechanically stressed DNANat CommunDecember 8, 2025Huadong Jiang, Fei He, Nannan Kong, Jie Long, Yu Ching Poon, Rajvee Shah Punatar, Zhichun Xu, Yuanliang Zhai, Stephen C. West, Artem K. Efremov, et al.mouse anti-MKLP1 (1:200, Santa Cruz Biotechnology sc-390113), rabbit anti-PICH (1:100, Cell Signaling 8886S), mouse anti-RPA (1:1000, Abcam ab2175), rabbit anti-53BP1 (1:1000, Abcam ab36823), mouse anti-Cyclin

(2) The interplay of the translocase activity and protein recruitment function of PICH in ultrafine anaphase bridge resolution and genomic stabilityNucleic Acids ResearchJanuary 24, 2025Nannan Kong, Kun Chen, Primrose Chanboonyasitt, Huadong Jiang, Ka Yan Wong, Hoi Tang Ma, Ying Wai ChanAbcam, #ab290), mouse anti-GFP (1:1000, Roche, #11814460001), rabbit anti-PICH (1:1000, Cell Signaling, #8886), mouse anti-PICH (1:1000, Millipore, #04–1540), rabbit anti-OsTIR1 (1:1000, MBL, #PD048), rabbit anti-53BP1

(3) Degradation‐Based Protein Profiling: A Case Study of CelastrolAdvanced ScienceJuly 1, 2024Zhihao Ni, Yi Shi, Qianlong Liu, Liguo Wang, Xiuyun Sun, Yu Raoanti‐NEK7 (Abcam, ab133514), anti‐OGA (Abcam, ab124807), anti‐CIP2A (Abcam, ab99518), anti‐PICH (CST, 8886S), anti‐NUR77 (Abcam, ab283264), and anti‐β‐Actin (ABclonal, AC026) antibody diluted in the corresponding

(4) PICH deficiency limits the progression of MYC-induced B-cell lymphomaBlood Cancer JournalJanuary 23, 2024María Castejón-Griñán, Eliene Albers, Lucía Simón-Carrasco, Paula Aguilera, Mauro Sbroggio, David Pladevall-Morera, Andreas Ingham, Ernest Lim, Alba Guillen-Benitez, Elena Pietrini, et al.previously [14]. The primary antibodies used for mouse samples were PICH (Cell Signaling Technology, 8886, D4G8; 1:50;), γH2AX (MilliporeSigma, 05-636, JBV301; 1:25,000;) and cleaved caspase-3 (Cell Signaling Technology

(5) Cdh1 Deficiency Sensitizes TNBC Cells to PARP InhibitorsGenesApril 30, 2022Li J, Lan M, Peng J, Xiong Q, Xu Y, Yang Y, Zhou Y, Liu J, Zeng Z, Yang X, et al.Proteintech, Wuhan, China); anti-GAPDH (60004-1-1g, 1:5000 WB, Proteintech, Wuhan, China), and anti-PICH(8886S, 1:200 IF, Cell Signaling); the secondary antibodies conjugated to horseradish peroxidase were used

(6) PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon ResponseAdvanced science (Weinheim, Baden-Wurttemberg, Germany)March 1, 2022Geng X, Zhang C, Li M, Wang J, Ji F, Feng H, Xing M, Li F, Zhang L, Li W, et al.(Santa Cruz Biotechnology, sc‐130300), GAPDH (Proteintech, 60004), PICH (Cell Signaling Technology, 8886), cGAS (Cell Signaling Technology, 31659), STING (Cell Signaling Technology, 50907), IFIT1 (Origene,

(7) Parental genome unification is highly error-prone in mammalian embryosCellMay 27, 2021Cavazza T, Takeda Y, Politi AZ, Aushev M, Aldag P, Baker C, Choudhary M, Bucevičius J, Lukinavičius G, Elder K, et al.(Merck #MAB3422), mouse anti-γ-tubulin at 1:250 (Sigma-Aldrich #T5326), rabbit anti-Sun1 at 1:100 (CST #8886), rabbit anti-Lamin B1 at 1:100 (Abcam #ab16048) and mouse anti-Lamin A/C at 1:50 (Sigma-Aldrich #MABT1340),

(8) Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic LethalityCell reportsSeptember 18, 2018Albers E, Sbroggiò M, Pladevall-Morera D, Bizard AH, Avram A, Gonzalez P, Martin-Gonzalez J, Hickson ID, Lopez-Contreras AJ.caspase-3 (1/750; Cell Signaling Technology, 9661) and PICH (D4G8; 1/50; Cell Signaling Technology, 8886). IHC reaction was developed using 3,3′-diaminobenzidine tetrahydrochloride (DAB) (Chromomap DAB, Ventana,

(9) Overcoming chemoresistance in pancreatic cancer cells: role of the bitter taste receptor T2R10Journal of CancerJanuary 1, 2018Stern L, Giese N, Hackert T, Strobel O, Schirmacher P, Felix K, Gaida MM.

(10) Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrationsNature cell biologyJanuary 1, 2018Chan YW, Fugger K, West SC.human anti-centromere CREST (1:1000, Immunovision HCT-0100); rabbit anti-PICH (1:100, Cell Signaling 8886), rabbit anti-TREX1 (1:1000, Abcam ab185288), rabbit anti-MKLP1 (1:1000, Santa Cruz sc-867). Secondary

(11) Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating neviNature communicationsSeptember 21, 2017Yeh I, Lang UE, Durieux E, Tee MK, Jorapur A, Shain AH, Haddad V, Pissaloux D, Chen X, Cerroni L, et al.http://1degreebio.org/reagents/product/8886/?qid=1704451), MEK (Santa Cruz Biotechnology, sc436; http://1degreebio.org/reagents/product/8886/?qid=1704451), phospho-MEK (Cell Signaling, #9121; https://www.antibodypedia.com/gene/3543/MAP2K2/antibody/107819/9121;

(12) Retracted: Effects of miR‐145‐5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI 3K/ AKT pathwaysCancer MedicineApril 1, 2017Sha Liu, Guozhen Gao, Dexiong Yan, Xiangjun Chen, Xingwei Yao, Shuzhong Guo, Guirong Li, Yu Zhao

(13) PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosisNature CommunicationsDecember 8, 2015Christian F. Nielsen et al.indirect immunofluorescence microscopy were as follows: mouse anti-PICH (04-1540, Millipore, 1:100), rabbit anti-PICH (8886S, Cell Signaling, 1:100), guinea pig anti-PICH (in-house, 1:400) mouse anti-β-tubulin (T4026, Sigma,

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PICH (D4G8) Rabbit mAb

PICH (D4G8) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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PICH (D4G8) Rabbit mAb from Cell Signaling Technology

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