Anti-ONECUT1 Antibody, Rabbit Polyclonal from AAA Biotech, LLC

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Anti-ONECUT1 Antibody, Rabbit Polyclonal

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The Anti-ONECUT1 Antibody, Rabbit Polyclonal from AAA Biotech, LLC is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Anti-ONECUT1 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, and Immunohistochemistry.

Description

ONECUT1 (HNF-6) is the prototype of a new class of homeodomain transcription factors, that controls the development of pancreatic ducts during mouse development. ONECUT1 protein was expressed in normal acinar and ductal cells, but neither in the cancer cells of PDAC tissues nor in 7 of 8 cultured pancreatic cancer cell lines.ONECUT1 expression is lost in pancreatic cancer cells, suggesting a tumor suppressor function in this malignancy