Description
Product Characteristics: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a p
Alias Symbols: DKFZp686P0638, DKFZp761B2423, MY038, P2P-R, RBQ-1, PACT, SNAMA
Protein Interaction Partner: CSTF3, CSTF2, CPSF2, CPSF1, CPSF4, UBC, HECW2, SRPK2, CLK3, CLK2, NEK6, MMS19, ZFYVE9, GRB2, PSME1, ATIC, NUBP2, CUL1, SPP1, VAV2, SUMO2, KHDRBS3, MAD2L2, PIAS1, UBE2I, TPT1, SMN1, SRSF7, RBP4, PLG, NDUFB9, HSPA4, HP, GLUL, CAPZA2, ASGR1, APOH, WBSCR16, A
Protein Size: 1792
Target Information: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]