IL-4 (OX81) Antibody sc-53084 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIL-4 (OX81) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-53084
Antibody TypePrimary Antibodies
Quantity200 µg/ml
CloneOX81
ApplicationsWB, IP, IF, IHC(P), FCM, ELISA
Reactivitymouse, rat
FormatPurified
Conjugate/TagUnconjugated
ClonalityMonoclonal
Hostmouse
TargetIL-4
IsotypeIgG1
NCBI Full Gene Nameinterleukin 4
NCBI Gene AliasesIl4e12

Questions and Answers

Can this IL-4 antibody be used for immunohistochemistry in mouse models?

Yes, the IL-4 (OX81) antibody has been successfully utilized in immunohistochemistry applications, as demonstrated in studies involving mouse models. For instance, it was used at a dilution of 1:200 to assess IL-4 expression in various tissues, highlighting its effectiveness in this application (, ).

Is this antibody effective for detecting IL-4 in inflammatory conditions?

The IL-4 antibody has been shown to work effectively in detecting IL-4 levels in various inflammatory contexts. For example, it was used in studies examining the role of IL-4 in allergic responses and inflammatory cytokine profiles, indicating its relevance in research focused on immune responses and inflammation (, ).

What species can this antibody be used with?

The IL-4 antibody is reactive with mouse and rat tissues, making it suitable for experiments involving these species. This reactivity has been confirmed in multiple studies that utilized the antibody in mouse models to investigate immune responses (, ).

Has this antibody been cited in any significant research studies?

Yes, the IL-4 (OX81) antibody has been cited in at least 20 scientific articles, indicating its widespread use and acceptance in the research community for studies related to cytokine signaling and immune responses (, ).

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Probiotic DNA epigenetically modulates KDM4A degradation to mitigate airway allergyiScienceDecember 19, 2025Huanping Zhang, Xiaoyao Li, Mingxian Zhang, Xiaoxue Chen, Lihua Mo, Le Liu, Hanqing Zhang, Gaohui Wu, Qinmiao Huang, Yu Liu, et al.,Santa Cruz Biotech,"sc-390756, AF700" CD127,Santa Cruz Biotech,"sc-514445, AF488" IL-4,Santa Cruz Biotech,"sc-53084, AF-594" IL-5,Santa Cruz Biotech,"sc-398334, AF648" IL-13,Santa Cruz Biotech,"sc-393365, AF680" LAG3,Santa Cruz

(2) Zn64 aspartate modulates inflammation, tryptophan metabolism, and pancreatic function in diet-induced obesitySci RepDecember 3, 2025Max Temnik, Sergey Gurin, Leonid Magidenko, Alexandr Balakin, Roman Byshovets, Olesia Kalmukova, Tetiana Vovk, Tetiana Halenova, Nataliia Raksha, Olexiy Savchukinterleukins (IL-1β (sc-52012), IL-6 (sc-32296), IL-10 (sc-32815), IL-12 (sc-365389), IFN-γ (sc-74106), IL-4 (sc-53084), TGF-β (sc-374433), resistin (sc-16117), and ghrelin (sc-517596), Santa Cruz Biotechnology, USA) was

(3) Inhibition of miR-4284 could reduce apoptosis and neuroinflammation by targeting APBA1/JAK1/STAT3 signaling in Alzheimer’s diseaseCell & BioscienceOctober 31, 2025Jiyun Choi, Jinsu Hwang, Dohee Kim, Eunjae Jang, Geupil Jang, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang,Santa Cruz Biotechnology,sc52746,1:1000 IL-1β,Santa Cruz Biotechnology,sc52012,1:1000 IL-4,Santa Cruz Biotechnology,sc53084,1:1000 IL-10,Santa Cruz Biotechnology,sc32815,1:1000 β-actin,Cell Signaling Technology,5125,1:3000 Horseradish

(4) Dust mite antigens endow dendritic cells with the capacity to induce a Th2 response by regulating their methylation profilesCell Communication and SignalingDecember 18, 2024Xiwen Zhang, Haoyue Zheng, Yixuan Dong, Hanqing Zhang, Le Liu, Yuanyi Zhang, Lingzhi Xu, Bailing Xie, Lihua Mo, Yu Liu, et al.B220 (sc-70712, AF594), CD3 (sc-20047, AF488), CD4 (sc-19641, AF546), CD25 (sc-393326, AF594), IL-4 (sc-53084, AF648), IL-5 (sc-398334, AF680), IL-13 (sc-393365, AF790), and CD62L (sc-13505, AF648) were purchased

(5) The effects of resistance training on cardiovascular factors and anti-inflammation in diabetic ratsHeliyonSeptember 15, 2024Jin Yoo, Jinsu Hwang, Jiyun Choi, Mahesh Ramalingam, Haewon Jeong, Sujeong Jang, Han-Seong Jeong, Daeyeol Kimab259862, abcam), anti-TNF-a (1:1000, ab205587, abcam), IL-6 (1:1000, ab9324, abcam), anti-IL-4 (1:1000, sc-53084, Santa Cruz Biotechnology), and anti-IL-10 (1:1000, A2171-100, ABclonal Science, Inc., Hubei, China).

(6) Effect of Exposure to Particulate Matter on the Ocular Surface in an Experimental Allergic Eye Disease Mouse ModelBioengineering (Basel)May 16, 2024Basanta Bhujel, Seheon Oh, Woojune Hur, Seorin Lee, Ho Seok Chung, Hun Lee, Jin Hyoung Park, Jae Yong KimAfter that, they were then incubated at 4 °C overnight with antibodies against IL-4 (1:200, Catalog No.sc-53084; Santa Cruz Biotechnology, Dallas, TX, USA), IL-5 (1:100, Catalog No. SC 398334; Santa Cruz Biotechnology,

(7) Plk2-mediated phosphorylation and translocalization of Nrf2 activates anti-inflammation through p53/Plk2/p21(cip1) signaling in acute kidney injuryCell biology and toxicologyAugust 1, 2023Kim DE, Byeon HE, Kim DH, Kim SG, Yim H.(Cell Signaling Technology, 4976), Mdm2 (Santa Cruz Biotechnology, sc-965), IL4 (Santa Cruz Biotechnology, sc-53084), IL10 (Santa Cruz Biotechnology, sc-365858), Histone H1 (Santa Cruz Biotechnology, sc-8030), α-tubulin

(8) Effects of a Peptide Derived from the Primary Sequence of a Kallikrein Inhibitor Isolated from Bauhinia bauhinioides (pep-BbKI) in an Asthma-COPD Overlap (ACO) ModelInternational journal of molecular sciencesJuly 9, 2023Silva LLSD, Barbosa JAS, João JMLG, Fukuzaki S, Camargo LDN, Dos Santos TM, Campos EC, Costa AS, Saraiva-Romanholo BM, Bezerra SKM, et al.

(9) IL-4 induces reparative phenotype of RPE cells and protects against retinal neurodegeneration via Nrf2 activationCell death & diseaseDecember 20, 2022Zhou T, Yang Z, Ni B, Zhou H, Xu H, Lin X, Li Y, Liu C, Ju R, Ge J, et al.performed as previously described [64]. Primary antibodies included anti-IL-4 antibody (Santa Cruz, sc-53084), anti-IL-4Rα antibody (Santa Cruz, sc-28361), anti-Nrf2 (Abcam, ab137550), anti-p-Nrf2 antibody (Abcam,

(10) Overexpression of helper T cell type 2-related molecules in the skin of patients with eosinophilic dermatosis of hematologic malignancyJournal of the American Academy of DermatologyOctober 1, 2022Maglie R, Ugolini F, De Logu F, Nassini R, Simi S, Nardiello P, Pasqualini E, Baroni G, Del Bianco E, Massi D, et al.

(11) Oral administration of Faecalibacterium prausnitzii and Akkermansia muciniphila strains from humans improves atopic dermatitis symptoms in DNCB induced NC/Nga miceScientific reportsMay 5, 2022Lee Y, Byeon HR, Jang SY, Hong MG, Kim D, Lee D, Shin JH, Kim Y, Kang SG, Seo JG.#ab196990, Abcam, USA), anti-ZO-1 (1:200 dilution, #61-7300, Invitrogen, USA), anti-IL-4 (1:100 dilution, #SC-53084, Santa Cruz Biotechnology, USA), and anti-Claudin-1 (1:100 dilution, #SC-166338, Santa Cruz Biotechnology,

(12) Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG(35-55)-Induced EAEInternational journal of molecular sciencesAugust 31, 2021Rajendran R, Rajendran V, Giraldo-Velasquez M, Megalofonou FF, Gurski F, Stadelmann C, Karnati S, Berghoff M.USA" Anti-IL-1β,Mouse,"17, 31 kDa",WB,12242,"Cell Signaling Tech, MA, USA" Anti-IL-4,Mouse,18 kDa,WB,sc-53084,"Santa Cruz Biotech, CA, USA" Anti-IL-6,Rabbit,24 kDa,WB,12912,"Cell Signaling Tech, MA, USA" Anti-IL-12,Rat,70

(13) MBP-activated autoimmunity plays a role in arsenic-induced peripheral neuropathy and the potential protective effect of mecobalaminEnvironmental toxicologyJune 1, 2021He Q, Chen B, Chen S, Zhang M, Duan L, Feng X, Chen J, Zhou L, Chen L, Duan Y.

(14) Effects of hypothermia on inflammatory cytokine expression in rat liver following asphyxial cardiac arrestExperimental and therapeutic medicineJune 1, 2021Park Y, Ahn JH, Cho JH, Tae HJ, Lee TK, Kim B, Lee JC, Park JH, Shin MC, Ohk TG, et al.anti-IL-2 (Cat. no. sc-133118, diluted 1:200; Santa Cruz Biotechnology, Inc.), mouse anti-IL-4 (Cat. no. sc-53084, diluted 1:200; Santa Cruz Biotechnology, Inc.) and mouse anti-IL-13 (Cat. no. sc-393365, diluted 1:200;

(15) Chimeric antigen-guiding extracellular vesicles eliminate antigen-specific Th2 cells in subjects with food allergyThe World Allergy Organization journalMarch 1, 2021Zhang YY, Mo LH, Yang G, Liu JQ, Liu ZQ, Yang LT, Ran PX, Liu ZG, Yang PC.

(16) Maternal high-fat diet activates hepatic interleukin-4 in rat male offspring accompanied by increased eosinophil infiltrationAmerican journal of physiology. Gastrointestinal and liver physiologyJanuary 1, 2021Wang H, Xu GB, Chen H, Pan YX.

(17) Clinical and Immunological Factors That Distinguish COVID-19 From Pandemic Influenza A(H1N1)Frontiers in immunologyJanuary 1, 2021Choreño-Parra JA, Jiménez-Álvarez LA, Cruz-Lagunas A, Rodríguez-Reyna TS, Ramírez-Martínez G, Sandoval-Vega M, Hernández-García DL, Choreño-Parra EM, Balderas-Martínez YI, Martinez-Sánchez ME, et al.(H-153): sc-7884, Santa Cruz Biotechnology Inc., Santa Cruz, CA), anti-IL-4 (IL-4 Antibody (OX81): sc-53084, Santa Cruz Biotechnology Inc., Santa Cruz, CA), and anti-IL-17A (Anti-IL-17 antibody (ab91649), Abcam,

(18) Cold stress promotes IL-33 expression in intestinal epithelial cells to facilitate food allergy developmentCytokineDecember 1, 2020Liu JQ, Hu TY, Diao KY, Yu D, Song YN, Mo LH, Yang G, Liu ZQ, Liu ZG, Yang PC.

(19) Berberine ameliorates obesity-induced chronic inflammation through suppression of ER stress and promotion of macrophage M2 polarization at least partly via downregulating lncRNA GomafuInternational immunopharmacologySeptember 1, 2020Han YB, Tian M, Wang XX, Fan DH, Li WZ, Wu F, Liu L.

(20) Tanshinone IIA Promotes M2 Microglia by ERβ/IL-10 Pathway and Attenuates Neuronal Loss in Mouse TBI ModelNeuropsychiatric disease and treatmentJanuary 1, 2020Chen M, Chen Q, Tao T.

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IL-4 (OX81) Antibody

IL-4 (OX81) Antibody from Santa Cruz Biotechnology, Inc.

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Questions and Answers

Santa Cruz Biotechnology, Inc.

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IL-4 (OX81) Antibody from Santa Cruz Biotechnology, Inc.

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