Smad1/2/3 (H-2) Antibody sc-7960 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSmad1/2/3 (H-2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-7960
NCBI Gene AliasesMlp1, JV18, MusMLP, JV4-1, BSP-1, Mad1, JV18-1, dwf-A, 7120426M23Rik, MADR1, MADR2, Smad-2, HsT17436, JV41, hSMAD3, hSMAD2, mMad2, mad3, Madr1, Madr2, MADH3, MADH2, MADH1, hMAD-3, hMAD-2, HSPC193, JV15-2, Madh3, Madh2, Madh1, LDS6, LDS3, CHTD8, BSP1, mMad1, LDS1C
Antibody TypePrimary Antibodies
Reactivitymouse, rat, human, mink
CloneH-2
ApplicationsWB, IP, IF, IHC(P), ELISA
Quantity200 µg/ml
Hostmouse
FormatPurified
ClonalityMonoclonal
NCBI Full Gene NameSMAD family member 1, SMAD family member 3, SMAD family member 2
TargetSmad1
IsotypeIgG2a
Conjugate/TagUnconjugated

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Theoretical-Experimental Analysis to Elucidate the Mechanism of Action of Novel Anabolic AgentsMoleculesNovember 20, 2025Israel Quiroga, Maura Cardenas-Garcia, María Guadalupe Hernández-Linares, Gabriel Guerrero-Luna, Fermín Flores-Manuelanalysis, the expression of pTNF-α (Santa Cruz Biotechnology, sc-133192, Santa Cruz, CA, USA), pSMAD1/2/3 (sc-7960), pMAFbX (sc-166806), and pAKT (sc-514032) was evaluated using non–phospho-specific antibodies to quantify

(2) Spatial transcriptomics reveals Inhba/Smad2/E2f4 axis in Lrp2high thecal cell proliferation in androgen-induced PCOS miceFront Cell Dev BiolAugust 4, 2025Man Luo, Xiaona Tian, Li Li, Guomei Zhang, Wenzhi Liu, Linlin Mei, Haoran Li, Xiaoyan You, Dongmei Zhang, Mengsi Zhou, et al.antibodies against Inhba (1:200; Santa Cruz, Cat. No. sc-166503), Smad2 (1:300; Santa Cruz, Cat. No. sc-7960), and E2f4 (1:300; Santa Cruz, Cat. No. sc-69685) were incubated overnight at 4°C. After washing, cells

(3) The platinum coordination complex inhibits cell invasion-migration and epithelial-to-mesenchymal transition by altering the TGF-β-SMAD pathway in colorectal cancerFrontiers in PharmacologyNovember 8, 2023Maha-Hamadien Abdulla, Aminah Ahmad Alzailai, Mansoor-Ali Vaali-Mohammed, Rehan Ahmad, Sabiha Fatima, Ahmed Zubaidi, Thamer bin Traiki, Amer Mahmood, Reem Hamoud Alrashoudi, Zahid Khan(Santa Cruz Biotechnology, sc-6260); Phospho-SMAD3 (Santa Cruz Biotechnology, sc- 517575); SMAD3 (Santa Cruz Biotechnology, sc-7960); and β-Actin, the internal control (Santa Cruz Biotechnology, sc-47778). After overnight incubation,

(4) Single-Dose Treatment with Rapamycin Preserves Post-Ischemic Cardiac Function through Attenuation of Fibrosis and Inflammation in Diabetic RabbitInternational journal of molecular sciencesMay 19, 2023Samidurai A, Saravanan M, Ockaili R, Kraskauskas D, Lau SYV, Kodali V, Ramasamy S, Bhoopathi K, Nair M, Roh SK, et al.(sc-52893), galectin-3 (B2C10; sc-32790), TIMP-1 (2A5; sc-21734), MYH (b-5; sc-376157) and Smad 1/2/3 (H-2; sc-7960), purchased from Santa Cruz Biotechnology, Inc., Dallas, TX, USA. GAPDH (D4C6R; Mouse mAb #97166) was

(5) Stage-specific requirement for METTL3-dependent m(6)A modification during dental pulp stem cell differentiationJournal of translational medicineDecember 16, 2022Luo H, Liu W, Zhou Y, Zhang Y, Wu J, Wang R, Shao L.Factor 2 (RUNX2, sc-390351, 1:1000); Dentin Sialophosphoprotein (DSPP, sc-73632, 1:1000); Smad1/2/3 (sc-7960, 1:1000); p-Smad3 (sc-517575, 1:1000) were obtained from Santa Cruz Biotechnology. GAPDH (60004-1-Ig,

(6) Epigallocatechin gallate ameliorates tetrahydrochloride-induced liver toxicity in rats via inhibition of TGFβ / p-ERK/p-Smad1/2 signaling, antioxidant, anti-inflammatory activitySaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical SocietySeptember 1, 2022Mostafa-Hedeab G, Ewaiss Hassan M, F Halawa T, Ahmed Wani F.Pleasanton CA, USA, Catalog # P00030) and Smad1/2 antibody (Santa Cruz Biotechnology, Inc. Catalog # sc-7960). Incubation was done in 5% nonfat dry milk, Tris-HCL, 0.1% Tween 20 for 1 hr. This was followed by

(7) miRNA expression analysis in the human heart: Undifferentiated progenitors vs. bioptic tissues-Implications for proliferation and ageingJournal of cellular and molecular medicineSeptember 1, 2021Iannolo G, Sciuto MR, Cuscino N, Carcione C, Coronnello C, Chinnici CM, Raffa GM, Pilato M, Conaldi PG.Santa Cruz Biotechnology, Texas, USA), mouse anti‐Yap1 (sc‐376830, 1/500; Santa Cruz Biotechnology), mouse anti‐Smad1/2/3 (sc‐7960, 1/500; Santa Cruz Biotechnology), rabbit anti‐cyclin D1 (E3P5S #55506, 1/1000; Cell Signaling) and

(8) Rehmannia Radix Extract Relieves Bleomycin-Induced Pulmonary Fibrosis in Mice via Transforming Growth Factor β1 (TGF-β1)Medical science monitor : international medical journal of experimental and clinical researchDecember 1, 2020Hu X, Zhu D.

(9) Alleviation of Inflammatory Response of Pulmonary Fibrosis in Acute Respiratory Distress Syndrome by Puerarin via Transforming Growth Factor (TGF-β1)Medical science monitor : international medical journal of experimental and clinical researchAugust 31, 2019Hu X, Huang X.

(10) Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem CellsStem cell reportsJanuary 8, 2019Narayana YV, Gadgil C, Mote RD, Rajan R, Subramanyam D.Santa Cruz, goat), TGF-βR1 (sc-398, Santa Cruz, rabbit), NANOG (sc-30328, Santa Cruz, goat), SMAD2/3 (sc-7960, Santa Cruz, mouse), RAB7 (sc-81922, Santa Cruz, rabbit), OCT3/4 (no. 2849, Cell Signaling Technology,

(11) DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signalingOncogeneMarch 1, 2017Chan DW, Hui WW, Wang JJ, Yung MM, Hui LM, Qin Y, Liang RR, Leung TH, Xu D, Chan KK, et al.FOXM1 (sc-502), p21WAF1/CIP1 (sc-397), p15Ink4B(sc-271791), p18Ink4c(sc-865), p27Kip1(sc-528), SMAD2 (sc-7960) and SMAD4 (sc-7966) (Santa Cruz Biotechnology, Inc.), DLX1 (PA5-28899, Thermo Scientific, Waltham,

(12) Effective treatment of polydatin weakens the symptoms of collagen-induced arthritis in mice through its anti-oxidative and anti-inflammatory effects and the activation of MMP-9Molecular medicine reportsDecember 1, 2016Li B, Wang XL.

(13) Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cellsJournal of biomedical scienceFebruary 27, 2016Chen CL, Chen CY, Chen YP, Huang YB, Lin MW, Wu DC, Huang HT, Liu MY, Chang HW, Kao YC, et al.

(14) Sika Deer Antler Collagen Type I-Accelerated Osteogenesis in Bone Marrow Mesenchymal Stem Cells via the Smad PathwayEvidence-based complementary and alternative medicine : eCAMJanuary 1, 2016Li N, Zhang M, Drummen GP, Zhao Y, Tan YF, Luo S, Qu XB.anti-ALP (SC-98652), anti-OC (SC365797), anti-BMP-2 (SC-137087), anti-Smad2 (SC-101153), anti-Smad3 (SC-7960), anti-Smad4 (SC-7966), and anti-𝛽actin (SC-130301) and were all acquired from Santa Cruz Biotechnology, Inc

(15) Measuring TGF-β Ligand Dynamics in Culture MediumMethods in molecular biology (Clifton, N.J.)January 1, 2016Feng Z, Zi Z, Liu X.anti-pSMAD2 antibody (Cell Signaling #3108S).Mouse anti-SMAD1/2/3 antibody (Santa Cruz Biotechnology SC-7960).Mouse anti-β-Actin antibody (Abcam AB-8226100, Cell Signaling #4967).Horse Radish Peroxidase conjugated

(16) Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cellsPloS oneJanuary 1, 2015Shankar J, Nabi IR.Transduction Laboratories; anti–β-actin was from Sigma, anti-vimentin (ab11256) was from abCam. SMAD1/2/3 (Sc-7960), SNAI 1 (Sc-28199), RhoA (Sc-418), c-Myc (Sc-789) antibodies were from Santa Cruz. Alexa488–, Alexa568–,

(17) Euphol from Euphorbia tirucalli Negatively Modulates TGF-β Responsiveness via TGF-β Receptor Segregation inside Membrane RaftsPloS oneJanuary 1, 2015Chen CL, Chen YP, Lin MW, Huang YB, Chang FR, Duh TH, Wu DC, Wu WC, Kao YC, Yang PH.

(18) Ets Related Gene and Smad3 Proteins Collaborate to Activate Transforming Growth Factor-Beta Mediated Signaling Pathway in ETS Related Gene-Positive Prostate Cancer CellsJournal of pharmaceutical sciences and pharmacologySeptember 1, 2014Fang J, Xu H, Yang C, Morsalin S, Kayarthodi S, Rungsrisuriyachai K, Gunnal U, Mckenzie B, Rao VN, Reddy ES.

(19) Lyn mitigates mouse airway remodeling by downregulating the TGF-β3 isoform in house dust mite modelsJournal of immunology (Baltimore, Md. : 1950)December 1, 2013Li G, Fox J 3rd, Liu Z, Liu J, Gao GF, Jin Y, Gao H, Wu M.

(20) Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific mannerExperimental cell researchNovember 15, 2013Browne JA, Liu X, Schnaper HW, Hayashida T.

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Smad1/2/3 (H-2) Antibody

Smad1/2/3 (H-2) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Smad1/2/3 (H-2) Antibody from Santa Cruz Biotechnology, Inc.

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