VDR (D-6) Antibody sc-13133 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemVDR (D-6) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13133
NCBI Gene AliasesNr1i1, PPP1R163, NR1I1
Antibody TypePrimary Antibodies
CloneD-6
Reactivitymouse, rat, human
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P)
Hostmouse
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
NCBI Full Gene Namevitamin D receptor, vitamin D (1,25-dihydroxyvitamin D3) receptor
TargetVDR
IsotypeIgG2a

Questions and Answers

What applications can I use this VDR antibody for in my experiments?

The VDR (D-6) antibody has been shown to work effectively in various applications, including Western blotting, immunofluorescence, immunohistochemistry, and immunoprecipitation.

Has this antibody been used in any specific studies related to vitamin D receptor signaling?

Yes, the VDR (D-6) antibody has been utilized in studies investigating the role of vitamin D in regulating fibroblast growth factor 23 synthesis in bone cells, as well as its effects on retinal pericyte proliferation and migration, indicating its relevance in vitamin D receptor signaling pathways.

Can this antibody detect VDR in different species?

The VDR (D-6) antibody is reactive with multiple species, including humans, mice, and rats, making it suitable for comparative studies across these organisms.

Are there any notable findings from research using this antibody?

Research utilizing the VDR (D-6) antibody has demonstrated that vitamin D receptor signaling can inhibit NLRP3 inflammasome activation, highlighting its potential role in regulating inflammatory responses. Additionally, it has been shown to be necessary for mitochondrial function and cell health, emphasizing the broader implications of VDR in cellular processes.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Modulators of Airway Remodeling: The Role of Caffeine and CalcitriolInternational Journal of Molecular SciencesMarch 28, 2026Marharyta Sobczak, Joanna Wieczfińska, Rafał PawliczakE-cadherin (sc-8426), GAPDH (sc-47724), MMP-9 (sc-10737), Vimentin (sc-6260), MMP-2 (sc-13594), and VDR (sc-13133), were purchased from Santa Cruz Biotechnology, Inc. (Dallas, TX, USA). Total RNA Mini kit was purchased

(2) Vitamin D is involved in regulating the limbic epileptogenesisBrain CommunicationsFebruary 16, 2026Shuya Qi, Mingyue Chen, Lihang Wei, Yang Wang, Xixia Liu, Bingyan Wang, Yuanyuan Liu, Guohe TanUSA) secondary antibodies for 2 h. The primary antibody used was a mouse anti-VDR antibody (1/500; SC-13133, Santa Cruz Biotechnology). For Nissl staining, brain sections were incubated with Neuro Trace 500/525

(3) Synergy in Immunostimulatory and Pro-Differentiation Effects of Vitamin D Analog and Fludarabine in Acute Myeloid LeukemiasCellsNovember 21, 2025Subhradeep Haldar, Artem Petruk, Aleksandra Marchwicka, Andrzej Kutner, Monika Biernat, Dariusz Wołowiec, Ewa Marcinkowska(mouse anti-actin, sc-8432, 1:100, 2 h, RT; mouse anti-HDAC2, sc-9959, 1:200, 1.5 h, RT; mouse anti-VDR, sc-13133, 1:250, 2.5 h, RT; mouse anti-STAT1, sc-464 and mouse anti-pSTAT1, sc-8394, both 1:100, overnight at

(4) Lactobacillus rhamnosus GG Administration Is Associated with Stimulation of Vitamin D/VDR Pathway and Mucosal Microbiota Modulation in Ulcerative Colitis Patients: A Pilot StudyPharmaceuticals (Basel)November 1, 2025Cristiano Pagnini, Manuele Gori, Maria Carla Di Paolo, Riccardo Urgesi, Claudia Cicione, Maria Zingariello, Francesca Arciprete, Viola Velardi, Elisa Viciani, Antonella Padella, et al.SYSTEM (# NB314KLD, Innovex Bioscience, Richmond, CA, USA) using the anti-VDR mouse monoclonal Ab (D-6, sc-13133, Santa Cruz Biotechnology, Dallas, TX, USA) diluted 1:100. Nuclear counterstaining was performed by

(5) The interplay between hormonal vitamin D and lipopolysaccharide signaling on human neutrophil transcriptional responsesFront ImmunolOctober 3, 2025Aiten Ismailova, Reyhaneh Salehi-Tabar, Nailya Ismailova, Olivia Dumas, James Saliba, Volker Blank, John H. WhiteDr. Volker Blank and used at a dilution of 1:20,000. BACH1 (sc-271211, Santa Cruz, 1:100) and VDR (sc-13133, Santa Cruz, 1:500) primary antibodies were purchased from Santa Cruz. The anti-rabbit and anti-mouse IgG HRP-linked

(6) Dysregulated vitamin D signaling in Hashimoto's thyroiditis: an integrated transcriptomic study in a Korean cohortFront Endocrinol (Lausanne)October 3, 2025Dong-Woo Lim, Ho-Jung Jeong, Jin Seok Lee, Min-Seo Choi, Sungsoon Fang, Jing-Hua Wang, Hojun Kim, Seok-Mo Kimthe slides were incubated overnight with a monoclonal VDR (D-6) antibody (1:100; SANTA CRUZ, Catalog #sc-13133, California, USA). Following PBS washes, the sections were counterstained with DAPI (100 μg/mL) to label

(7) Reticuline and Coclaurine Exhibit Vitamin D Receptor-Dependent Anticancer and Pro-Apoptotic Activities in the Colorectal Cancer Cell Line HCT116Curr Issues Mol BiolOctober 1, 2025Hind A. Alghamdi, Sahar S. Alghamdi, Maryam Hassan Al-Zahrani, Thadeo Trivilegio, Sara Bahattab, Rehab AlRoshody, Yazeid Alhaidan, Rana A. Alghamdi, Sabine Matou-Nasriand provided by Solarbio Science and Technology Co., Ltd., Beijing, China). Mouse primary anti-VDR (#sc-13133), cyclin A1 (#sc-271645), cyclin B1 (#sc-70898), cyclin D1 (#sc-8396) antibodies were provided by Santa Cruz Biotechnology Inc

(8) Vitamin D3 reduces the viability of cancer cells in vitro and retard the EAC tumors growth in micePLOS OneSeptember 8, 2025Vidya G. Bettada, Chaithanya G. Basavaraju, Shalini H. Doreswamy, SubbaRao V. Tulimilli, Rimshia Naaz, Siva Dallavalasa, Paramahans V. Salimath, Anjali Devi S. Bettadapura, Asha Srinivasan, Rajalakshmi Ramashetty, et al.Corporation, Madison, Wisconsin, USA. Antibodies for Western blot: Vitamin D receptor (VDR) (Cat# sc-13133), Cyclin D1(Cat# sc-8396), p21(Cat# sc-6246), were procured from Santa Cruz Biotechnology, Dallas USA;

(9) Vitamin D Reshapes Genomic Hierarchies in Skin Cells: lncRNA-Driven Responses in Carcinoma Versus Transcription Factor-Based Regulation in Healthy SkinInt J Mol SciJuly 10, 2025Anna M. Olszewska, Joanna I. Nowak, Paweł Domżalski, Kamil Myszczyński, Michał A. Żmijewskiantibodies (anti-STAT1, sc-136229; anti-p-STAT1 (Y701), sc-464; Santa Cruz Biotechnology, USA; anti-VDR sc-13133, Santa Cruz Biotechnology, USA; anti-RXRA A19105, ABclonal, Woburn, MA, USA) were applied overnight

(10) Vitamin D-regulated miRNA expression in tumoral and normal adjacent tissue of localized gastric cancer patients: the impact on survival and time to relapseTranslational Cancer ResearchJune 30, 2025Antía Cousillas Castiñeiras, Elena Gallardo Martín, Ana Fernández Montes, Marta Carmona Campos, Marta Covela Rúa, Mercedes Salgado Fernández, María Luz Pellón Augusto, José Carlos Méndez Méndez, Elena Brozos Vázquez, Nieves Martínez LagoPathology Department of the University Hospital of Santiago de Compostela. The monoclonal antibody D-6 (sc-13133, Santa Cruz Bio-Technology) was used in the analysis. Tumor cell staining was evaluated based on the

(11) Hypovitaminosis D Does Not Aggravate the Progression of Gentamicin-Induced Kidney Injury in RatsDiseasesJune 28, 2025Ana Lívia D. Maciel, Amanda L. Deluque, Beatriz M. Oliveira, Cláudia S. Souza, Heloísa D. C. Francescato, Cleonice Giovanini, Francisco J. A. de Paula, Terezila M. Coimbra, Rildo A. Volpiniand Tween-20). Blots were then incubated overnight at 4 °C with the primary antibodies anti-VDR (VDR sc-13133, 1:500, Santa Cruz Biotechnology, Dallas, TX, USA) and anti-CYP24A1 (H00001591-M02, 1:500; Abnova, Walnut,

(12) Hepatic-specific vitamin D receptor downregulation alleviates aging-related metabolic dysfunction-associated steatotic liver diseaseWorld J GastroenterolApril 14, 2025Feng Zhu, Bing-Ru Lin, Shi-Hua Lin, Chao-Hui Yu, Yun-Mei Yangantibodies; those from Santa Cruz Biotechnology (Dallas, TX, United States) included VDR antibodies (1:300, sc-13133); and those from Abcam (Cambridge, United Kingdom) included FASN antibodies (1:1000, ab128856). Quantitative real-time polymerase chain reaction

(13) Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancerCell Death DisFebruary 27, 2025Qi Wang, Dandan Li, Haixiu Ma, Zengyan Li, Juan Wu, Jinwan Qiao, Jun Liu, Jing Zhao, Ronghua Ma, Lin Tian, et al.Technology (CST, Boston, MA, USA). The additional antibodies used in this study included EMP1 (Cat# sc-13133, Santa Cruz, Dallas, TX, USA), NFκB (P65) (Cat# sc-7304, Santa Cruz, Dallas, TX, USA), p-IκBα and total

(14) The Association of VDR/FokI Gene Polymorphism and Protein Expression With Histopathological Alterations in Patients With Thyroid Colloid NoduleAnal Cell Pathol (Amst)February 18, 2025Mariwan F. Abdalfatah, Abdullah A. Shareef, Lana S. Saleh, Mustafa F. Rajab, Shukur W. Smail, Saman S. Abdulla, Harem Khdir Awla, Rivan H. Ishaac, Kazhal S. Ibrahim, Mazyar J. Ahmed, et al.anti-polyvalent, HRP kit (Thermo Fisher Scientific), and the specific VDR (D-6) mouse monoclonal antibody (sc-13133; Santa Cruz Biotechnology, Dallas, USA) at 1:100 dilution were used to detect VDR in patients and applied

(15) Immunohistochemical Expression of Vitamin D Receptors (VDRs) and Estrogen Receptor Beta 1 (ERβ1) in Molecular Subtypes of Triple-Negative Breast Cancer Tumors: A Cross-Sectional StudyCureusJanuary 18, 2025Shankaramurthy K N, Basavaraj B Devaranavadagi, Indira A Hundekaribinding. Mouse monoclonal antibodies targeting VDR at a 1:300 dilution, as previously described (anti-VDR, sc-13133, Santa Cruz Biotechnology, CA, USA) [16] and ERβ1 at a 1:50 dilution (ERβ1-sc-390243, Santa Cruz Biotechnology,

(16) 1,25‑Dihydroxyvitamin D3 mitigates the adipogenesis induced by bisphenol A in 3T3-L1 and hAMSC through miR-27-3p regulationInternational journal of obesity (2005)December 1, 2024Provvisiero DP, Negri M, Amatrudo F, Patalano R, Montò T, de Angelis C, Graziadio C, Pugliese G, de Alteriis G, Colao A, et al.antibodies at room temperature for 1 h. The specific primary antibodies were as follows: VDR (1:1000; #sc-13133, Santa Cruz), peroxisome proliferator-activated receptor-γ (PPARγ; 1:1000; #2443, Cell Signaling); CCAAT/enhancer-binding

(17) Vitamin D receptor and its antiproliferative effect in human pulmonary arterial hypertensionScientific ReportsNovember 10, 2024Maria Callejo, Daniel Morales-Cano, Miguel A. Olivencia, Gema Mondejar-Parreño, Bianca Barreira, Olga Tura-Ceide, Victor G. Martínez, Alvaro Serrano-Navarro, Laura Moreno, Nick Morrell, et al.room temperature. Samples were subsequently incubated with the primary antibody mouse anti-VDR (1:100, SC-13133, Santa Cruz, Dallas, USA) at 4 ºC overnight and then 15 min at 37 °C. Afterward, PASMC were incubated

(18) Absence of claudin-3 does not alter intestinal absorption of phosphate in micePflugers Archiv : European journal of physiologyOctober 1, 2024Radványi Z, Schnitzbauer U, Pastor-Arroyo EM, Hölker S, Himmerkus N, Bleich M, Müller D, Breiderhoff T, Hernando N, Wagner CA.Switzerland), claudin-7 (1:1000, #34–9100 Invitrogen), calbindin-D28k (1:500, #CB38 Swant), VDR (1:300, #sc-13133 Santa Cruz Biotechnology), or β-actin (1:15,000, #A1978 Sigma-Aldrich, Switzerland). Upon washing with

(19) SOX2, JAGGED1, β-Catenin, and Vitamin D Receptor Expression Patterns during Early Development and Innervation of the Human Inner EarInternational journal of molecular sciencesAugust 9, 2024Mikulić P, Ogorevc M, Petričević M, Kaličanin D, Tafra R, Saraga-Babić M, Mardešić S.USA)" Primary,Anti-Beta-catenin,Mouse,2677,1:200,"Cell Signaling Technology (CST), (Danvers, MA, USA)" Primary,Anti-Vitamin D Receptor,Mouse,sc-13133,1:50,"Santa Cruz Biotechnology, Dallas, TX, USA" Primary,Anti-JAGGED1,Goat,AF1277,1:100,"R&D Systems,Minneapolis,

(20) Association between vitamin D receptor polymorphisms, tight junction proteins and clinical features of adult patients with atopic dermatitisDermatology Practical & ConceptualJuly 31, 2024Teresa Grieco, Elisa Moliterni, Giovanni Paolino, Camilla Chello, Alvise Sernicola, Colin Gerard Egan, Fabrizio Nannipieri, Santina Battaglia, Marina Accoto, Erika Tirotta, et al.(Santa Cruz Biotechnology: Santa Cruz, CA, USA, sc-8146) diluted 1:50, mouse monoclonal anti-VDR antibody (Santa Cruz, sc-13133) diluted 1:100, rabbit polyclonal anti-VDR antibody (Abcam: Cambridge, United Kingdom, ab3508) diluted

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VDR (D-6) Antibody

VDR (D-6) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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VDR (D-6) Antibody from Santa Cruz Biotechnology, Inc.

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