IgG1 (2C11) Antibody sc-52003 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIgG1 (2C11) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-52003
Quantity100 µg/ml
Clone2C11
Reactivityhuman
ApplicationsIF
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
FormatPurified
Hostmouse
ClonalityMonoclonal
NCBI Full Gene Nameimmunoglobulin heavy constant gamma 1 (G1m marker)
TargetIgG1
IsotypeIgG1

Questions and Answers

Can this IgG1 antibody be used as a control in experiments involving immune receptor blocking?

Yes, the IgG1 (2C11) antibody has been used as an isotype-matched, irrelevant control in various studies, including those assessing the roles of TLR4 and mannose receptors in immune responses (, , ).

What specific applications has this antibody been shown to work in?

The IgG1 (2C11) antibody has been utilized in immunofluorescence applications, as indicated by its use in studies examining immune responses in human peripheral blood mononuclear cells and macrophages (, ).

Is there any evidence of this antibody being used in studies related to fungal infections?

Yes, the IgG1 (2C11) antibody has been referenced in studies investigating the immune response to fungal pathogens, specifically in the context of cytokine production by human immune cells when interacting with different Sporothrix species (, ).

What species does this antibody specifically react with?

The IgG1 (2C11) antibody is reactive with human proteins, specifically targeting the immunoglobulin heavy constant gamma 1 (IGHG1) gene, which is relevant in studies involving human immune responses ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Silencing of MNT1 and PMT2 Shows the Importance of O-Linked Glycosylation During the Sporothrix schenckii-Host InteractionJ Fungi (Basel)May 2, 2025Manuela Gómez-Gaviria, José A. Martínez-Álvarez, Iván Martínez-Duncker, Andrea Regina de Souza Baptista, Héctor M. Mora-Montescells. The antibodies used were IgG1 at a concentration of 10 µg mL−1 (Santa Cruz Biotechnology, Cat. No.sc-52003, to control experiments with anti-TLR4 and anti-MR antibodies), 10 µg mL−1 of IgG2ak antibody (Thermo-Fisher Scientific

(2) Silencing of Sporothrix schenckii GP70 Reveals Its Contribution to Fungal Adhesion, Virulence, and the Host-Fungus InteractionJournal of fungi (Basel, Switzerland)April 23, 2024López-Ramírez LA, Martínez-Álvarez JA, Martínez-Duncker I, Lozoya-Pérez NE, Mora-Montes HM.preincubation stage. Antibodies were IgG1 antibody (10 μg mL−1, Santa Cruz Biotechnology, Cat. No. sc-52003, used as a control in experiments where TLR4 and MR were blocked), 10 μg mL−1 IgG2aκ antibody (Thermo-Fisher Scientific

(3) Differential Recognition of Clinically Relevant Sporothrix Species by Human GranulocytesJournal of fungi (Basel, Switzerland)October 4, 2023Galván-Hernández AK, Gómez-Gaviria M, Martínez-Duncker I, Martínez-Álvarez JA, Mora-Montes HM.MA5-16528); isotype-matched, irrelevant IgG1 antibody (10 μg mL−1, Santa Cruz Biotechnology, Cat. No. sc-52003, used as a control in experiments where TLR4 was blocked), 10 μg mL−1 IgG2aκ antibody (Thermo-Fisher Scientific

(4) Differential Recognition of Clinically Relevant Sporothrix Species by Human Mononuclear CellsJournal of fungi (Basel, Switzerland)April 6, 2023García-Carnero LC, Martínez-Duncker I, Gómez-Gaviria M, Mora-Montes HM.controls, isotype-matched, irrelevant IgG1 antibodies (10 μg mL−1, Santa Cruz Biotechnology, Cat. No. sc-52003) were used in experiments where MR and TLR4 were blocked; meanwhile, 10 μg mL−1 of IgG2aκ (Thermo-Fisher Scientific

(5) Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic CellsInfection and drug resistanceJanuary 1, 2023Gómez-Gaviria M, Martínez-Duncker I, García-Carnero LC, Mora-Montes HM.MA5-16528), Isotype-matched, irrelevant IgG1 antibody (10 μg mL−1, Santa Cruz Biotechnology, Cat. No. sc-52003, used as a control in experiments where MR and TLR4 were blocked), 10 μg mL−1 IgG2aκ antibody (Thermo-Fisher Scientific

(6) Silencing of ROT2, the Encoding Gene of the Endoplasmic Reticulum Glucosidase II, Affects the Cell Wall and the Sporothrix schenckii-Host InteractionJournal of fungi (Basel, Switzerland)November 18, 2022López-Ramírez LA, Martínez-Duncker I, Márquez-Márquez A, Vargas-Macías AP, Mora-Montes HM.[20,54,63]. Isotype-matched, irrelevant IgG1 antibodies (10 μg mL−1, Santa Cruz Biotechnology, Cat. No. sc-52003) were used as a control in experiments where MR and TLR4 were blocked; 10 μg mL−1 IgG2aκ (Thermo-Fisher Scientific

(7) Mechanism of triptolide in treating ankylosing spondylitis through the anti‑ossification effect of the BMP/Smad signaling pathwayMolecular Medicine ReportsNovember 20, 2017Guilong Wang, Jing Cai, Jinshan Zhang, Cuiyun Lifollowing incubation, and 0.1 ml antibody solution (TNF‑ α, cat. no. sc‑52011; IL‑1β, cat. no. sc‑52022; IL‑6, cat. no. sc‑52003) from Santa Cruz Biotechnology, Inc. (Dallas, TX, USA) was added to each well prior to incubation at

(8) Sporothrix schenckii sensu stricto and Sporothrix brasiliensis Are Differentially Recognized by Human Peripheral Blood Mononuclear CellsFrontiers in microbiologyJanuary 1, 2017Martínez-Álvarez JA, Pérez-García LA, Mellado-Mojica E, López MG, Martínez-Duncker I, Lópes-Bezerra LM, Mora-Montes HM.fungal cells. Isotype matched, irrelevant IgG1 antibodies (10 µg/mL, Santa Cruz Biotechnology, Cat. No. sc-52003) were used as control for experiments assessing MR and TLR4; while IgG2 aκ (10 µg/mL, eBioscience, Cat.

(9) Role of Protein Glycosylation in Candida parapsilosis Cell Wall Integrity and Host InteractionFrontiers in microbiologyJanuary 1, 2016Pérez-García LA, Csonka K, Flores-Carreón A, Estrada-Mata E, Mellado-Mojica E, Németh T, López-Ramírez LA, Toth R, López MG, Vizler C, et al.(10 μg/mL, eBioscience, Cat. No. 14-4724-85) and IgG1(10 μg/mL, Santa Cruz Biotechnology, Cat. No. sc-52003) were used as controls for experiments assessing TLR2 and TLR4, respectively. All reagents used for

(10) Members of the Candida parapsilosis Complex and Candida albicans are Differentially Recognized by Human Peripheral Blood Mononuclear CellsFrontiers in microbiologyJanuary 1, 2015Estrada-Mata E, Navarro-Arias MJ, Pérez-García LA, Mellado-Mojica E, López MG, Csonka K, Gacser A, Mora-Montes HM.yeast cells. Isotype matched, irrelevant IgG1 antibodies (10 μg/mL, Santa Cruz Biotechnology, Cat. No. sc-52003) were used as controls for experiments assessing MR and TLR4. Despite all the reagents used for the

(11) Identification of an intrinsic determinant critical for maspin subcellular localization and functionPloS oneJanuary 1, 2013Dzinic SH, Kaplun A, Li X, Bernardo M, Meng Y, Dean I, Krass D, Stemmer P, Shin N, Lonardo F, et al.Cambridge, MA), protein A/G agarose beads (# sc2003, Santa Cruz, Santa Cruz, CA), normal mouse IgG (#sc52003, Santa Cruz), normal rabbit IgG (# sc3888, Santa Cruz) and DAPI (#10236276001, Roche Applied Science,

(12) E-cadherin protects primary hepatocyte spheroids from cell death by a caspase-independent mechanismCell transplantationJanuary 1, 2009Luebke-Wheeler JL, Nedredal G, Yee L, Amiot BP, Nyberg SL.

(13) Identification and elucidation of cross talk between SLAM Family Member 7 (SLAMF7) and Toll-like receptor (TLR) pathways in monocytes and macrophagesScientific reportsJanuary 1, 0001"Choe U, Pham Q, Kim YS, Yu L, Wang TTY."(OTI1F1) (Cat#:NBP2-45868) from Novus Biologicals, LCC (Centennial, CO, USA) and IgG1 control (Cat#:sc-52003) from Santa Cruz Biotechnology, Inc (Dallas, TX. USA). Cell culture and differentiation of monocyte

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IgG1 (2C11) Antibody

IgG1 (2C11) Antibody from Santa Cruz Biotechnology, Inc.

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Questions and Answers

Santa Cruz Biotechnology, Inc.

Citations (13)

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IgG1 (2C11) Antibody from Santa Cruz Biotechnology, Inc.

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