RAP1 (4C8/1) Antibody sc-53434 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRAP1 (4C8/1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-53434
NCBI Gene AliasesRAP1, DRIP5, Rap1
Antibody TypePrimary Antibodies
Clone4C8/1
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human
Hostmouse
FormatPurified
Conjugate/TagUnconjugated
ClonalityMonoclonal
NCBI Full Gene NameTERF2 interacting protein, telomeric repeat binding factor 2, interacting protein
TargetRAP1
IsotypeIgG2b

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Geranylgeranyl Transferase Inhibitors Mitigate Intestinal Radiation ToxicityInternational journal of radiation oncology, biology, physicsMarch 15, 2026McGinness K, Al-Anbaky Q, Larrey EK, Cholia RP, Rotenberry M, Cook H, Pineda EN, Du R, Boerma M, Pathak R.sc-398755, to detect unprenylated RAP1), and RAP1 Antibody (4C8/1) (Santa Cruz Biotechnology; Dallas, TX; sc-53434; to detect total RAP1), were used at a 1:1000 dilution for overnight incubation at 4 °C. Goat anti-rabbit IgG-HRP

(2) Modified hTERT treatment ameliorates pressure overload-induced heart failureEBioMedicineMarch 9, 2026Yinlong Zhao, Xiaolu Bao, Weiyao Xiong, Xin Wan, Qingying Yu, Teng Wang, Andrew C.H. Chang, Yangyang Liu, Yanqiu Wang, Ching Shang, et al.sc-517380), TFAM (1:1000, Proteintech, 22586-1-AP), TRF1 (1:1000, Abcam, ab192629), RAP1 (1:1000, Santa Cruz, sc-53434), TIN2 (1:1000, Proteintech, 11368-1-AP), POT1 (1:1000, Novus Biologicals, NB500-176), HA-tag (1:1000,

(3) Methylation-regulated tumor suppressor gene HOXB4 inhibits human lung adenocarcinoma A549 cell invasion and metastasis through the RAP1 signaling pathwayTranslational Cancer ResearchOctober 31, 2025Lingxiang Zhang, Zhong Xu, Shu Wu, Yamen ahmed Ahmed Muad, Weiyan Peng, Lin YeSanta Cruz Biotechnology (Santa Cruz, CA, USA), targeting the following proteins: HOXB4 (sc-271083), RAP1; (sc-53434), RAP1GAP (sc-166586), E-cadherin (sc-8426), N-cadherin (sc-59987), Vimentin (sc-373717), and GAPDH

(4) Umbelliferone as an effective component of Rhodiola for protecting the cerebral microvascular endothelial barrier in cSVDFrontiers in pharmacologyJanuary 1, 2025Tang L, Cheng H, Yang Q, Xie Y, Zhang Q.1:1000), p-AKT1 (Cell Signaling Technology, 4060T, Unites States, 1:2000), Rap1 (Santa Cruz Biotechnology, sc-53434, Unites States, 1:200), MMP9 (Proteintech, 10375, Unites States, 1:500), MMP2 (Santa Cruz Biotechnology,

(5) cAMP-Epac1 signaling is activated in DDAVP-induced endolymphatic hydrops of guinea pigsBrazilian journal of otorhinolaryngologyMay 1, 2023Chuan W, Yuan L, Wen J, Jianwei Z, Caiji W, Zeqi Z, Yalan L, Renlong J, Kang L, Wei L, et al.(SC-28326, Santa Cruz Biotechnology, Dallas, TX, 126 kDa, 1:200), and mouse anti-Rap1 primary antibody (SC-53434, Santa Cruz Biotechnology, 44 kDa, 1:200). Statistical analysis The SPSS 20.0 software package (IBM,

(6) Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeresNucleic acids researchFebruary 22, 2023Storchova R, Palek M, Palkova N, Veverka P, Brom T, Hofr C, Macurek L.Novus Biologicals; TRF2 (sc271710, for IF), TIN2 (sc73177, for IF), TPP1 (sc100597, for IF and WB), RAP1 (sc53434, for WB), PPM1D (sc376257, for IF and WB), PPM1D (sc20712, for IF) from Santa Cruz Biotechnology; Phospho-Histone

(7) The expression and significance of Epac1 and Epac2 in the inner ear of guinea pigsEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck SurgeryNovember 1, 2022Wang C, Li Y, Liu W, Wang C, Jiang W, Zhao Z, Li X, Qiao Y, Dai C.

(8) Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypesPLoS geneticsNovember 1, 2022Stock AJ, McDevitt RA, Puligilla C, Wang Y, Zhang Y, Wang K, Sun C, Becker KG, Lehrmann E, Wood WH 3rd, et al.ab 7260), respectively. Western blotting was employed to determine expression of RAP1 (Santa Cruz, sc-53434), TRF2 (Novus Biologicals, NB110-57130), GAPDH (ABclonal, AC027), β-ACTIN (Cell Signaling Technology,

(9) Exosomes Derived from Tumor Cells Initiate Breast Cancer Cell Metastasis and Chemoresistance through a MALAT1-Dependent MechanismJournal of oncologyJanuary 1, 2022Tao S, Bai Z, Liu Y, Gao Y, Zhou J, Zhang Y, Li J.#3132, Cell Signaling Technology, Beverly, MA, USA), Rap1 (mouse, dilution ratio of 1 : 100–1 : 1000, sc-53434, Santa Cruz Biotechnology, Inc., CA, USA), and GAPDH (rabbit, dilution ratio of 1 : 1000, #2118, Cell Signaling Technology

(10) Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biologyCommunications biologyNovember 19, 2021Yu EY, Zahid SS, Aloe S, Falck-Pedersen E, Zhou XK, Cheung NV, Lue NF.

(11) Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interactionCell reportsMay 18, 2021Sharma S, Mukherjee AK, Roy SS, Bagri S, Lier S, Verma M, Sengupta A, Kumar M, Nesse G, Pandey DP, et al.mouse monoclonal,Novus,Cat# NB110−68281; RRID:AB_1111093 RAP1 mouse monoclonal,Santa Cruz,Cat#4C8/1 SC−53434; RRID:AB_630189 POT1 mouse monoclonal,Santacruz,Cat#M1P1H5 SC−81711; RRID:AB_1128696 Monoclonal anti-FLAG

(12) Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapyNature communicationsDecember 13, 2019Khattar E, Maung KZY, Chew CL, Ghosh A, Mok MMH, Lee P, Zhang J, Chor WHJ, Cildir G, Wang CQ, et al.and KU80 (Cell Signaling Technology: #2180) were from Cell Signaling Technology. Rap1 (Santa Cruz: sc-53434 and sc-28197) was from Santa Cruz Biotechnology, TRF2 (Millipore: #05–521) and pATM (Millipore: #05–740)

(13) Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasisProtein & cellSeptember 1, 2019Zhang X, Liu Z, Liu X, Wang S, Zhang Y, He X, Sun S, Ma S, Shyh-Chang N, Liu F, et al.Image Lab software. The primary antibodies used for Western blotting in this study were anti-RAP1 (Santa Cruz, sc53434), anti-P16 (BD, 550834), anti-P21 (CST, 2947s), anti-β-actin (Santa Cruz, sc69879) and anti-β-tubulin

(14) Determination of local chromatin interactions using a combined CRISPR and peroxidase APEX2 systemNucleic acids researchMay 21, 2019Qiu W, Xu Z, Zhang M, Zhang D, Fan H, Li T, Wang Q, Liu P, Zhu Z, Du D, et al.anti-TRF1 (ab10579; Abcam), anti-TRF2 (sc-271710; Santa Cruz Biotechnology, Dallas, TX, USA), anti-RAP1 (sc-53434; Santa Cruz Biotechnology) and anti-POT1 (ab124784; Abcam). Stable isotope labeling by amino acids

(15) Proteome-wide Adaptations of Mouse Skeletal Muscles during a Full Month in SpaceJournal of proteome researchJuly 7, 2017Tascher G, Brioche T, Maes P, Chopard A, O'Gorman D, Gauquelin-Koch G, Blanc S, Bertile F.

(16) LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitroCell cycle (Georgetown, Tex.)January 17, 2017Wamsley JJ, Issaeva N, An H, Lu X, Donehower LA, Yarbrough WG.

(17) Heat-labile enterotoxin-induced activation of NF-κB and MAPK pathways in intestinal epithelial cells impacts enterotoxigenic Escherichia coli (ETEC) adherenceCellular microbiologyAugust 1, 2012Wang X, Gao X, Hardwidge PR.

(18) Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expressionNature cell biologyAugust 1, 2010Teo H, Ghosh S, Luesch H, Ghosh A, Wong ET, Malik N, Orth A, de Jesus P, Perry AS, Oliver JD, et al.

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RAP1 (4C8/1) Antibody

RAP1 (4C8/1) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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RAP1 (4C8/1) Antibody from Santa Cruz Biotechnology, Inc.

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